Patents by Inventor Diana Nguyen

Diana Nguyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220211495
    Abstract: An implantable prosthetic valve includes a radially collapsible and expandable annular frame having three commissure attachment posts and four rows of circumferential struts. The rows include a first row, a second row downstream of the first row, a third row downstream of the second row, and a fourth row downstream of the third row and defining an outflow end of the frame. Each row of circumferential struts includes angled struts arranged in a zig-zag pattern. A leaflet structure includes three leaflets forming three commissures, each commissure being connected to one of the commissure attachment posts only at locations along the commissure attachment posts between a first plane that is perpendicular to a longitudinal axis of the frame and intersects crowns of the third row of struts and a second plane that is perpendicular to the longitudinal axis and intersects crowns of the fourth row of struts.
    Type: Application
    Filed: March 25, 2022
    Publication date: July 7, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
  • Publication number: 20220110749
    Abstract: An implantable prosthetic valve includes a radially collapsible and expandable annular frame having three commissure attachment posts and four rows of circumferential struts. The rows include a first row, a second row downstream of the first row, a third row downstream of the second row, and a fourth row downstream of the third row and defining an outflow end of the frame. Each row of circumferential struts includes angled struts arranged in a zig-zag pattern. A leaflet structure includes three leaflets forming three commissures, each commissure being connected to one of the commissure attachment posts only at locations along the commissure attachment posts between a first plane that is perpendicular to a longitudinal axis of the frame and intersects crowns of the third row of struts and a second plane that is perpendicular to the longitudinal axis and intersects crowns of the fourth row of struts.
    Type: Application
    Filed: December 21, 2021
    Publication date: April 14, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
  • Patent number: 11213388
    Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: January 4, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
  • Publication number: 20210401571
    Abstract: A prosthetic heart valve includes an annular frame that has an inflow end and an outflow end and is radially compressible and expandable between a radially compressed configuration and a radially expanded configuration. The prosthetic heart valve further includes a leaflet structure positioned within the frame and secured thereto, and an outer sealing member mounted outside of the frame and adapted to seal against surrounding tissue when the prosthetic heart valve is implanted within a native heart valve annulus of a patient. The sealing member can include a mesh layer and pile layer comprising a plurality of pile yarns extending outwardly from the mesh layer.
    Type: Application
    Filed: August 31, 2018
    Publication date: December 30, 2021
    Inventors: Lien Huong Thi Hoang, Son V. Nguyen, Hien Tran Ngo, Vivian Tran, Russell T. Joseph, Dinesh L. Sirimanne, Kevin D. Rupp, Diana Nguyen-Thien-Nhon
  • Publication number: 20210353410
    Abstract: Systems, dies, and methods are provided for processing pericardial tissue. The method includes positioning a die-cut assembly over the pericardial tissue, the die-cut assembly including a die having a plate, a die pattern, and an opening, the die pattern attached to the plate, the opening formed in the plate to provide access to the pericardial tissue, and measuring a thickness of the tissue through the opening. The die-cut assembly may be mounted for automated vertical movement, and a platen on which the tissue is placed is capable of automated horizontal movement. Different target areas on the tissue can be assessed by measuring the thickness through the die, and when an area is deemed suitable the die pattern cuts a shape therefrom. The system is useful for cutting uniform thickness heart valve leaflets, and can be automated to speed up the process.
    Type: Application
    Filed: July 30, 2021
    Publication date: November 18, 2021
    Inventors: Oanh H. Nguyen, Ivan Jankovic, Diana Nguyen-Thien-Nhon, Juan C. Velez, Jon Boomgarden
  • Publication number: 20210322163
    Abstract: A prosthetic heart valve includes a frame, a valvular structure, and a skirt. The frame is movable between collapsed and expanded configurations and includes struts disposed between inflow and outflow ends, apices disposed at the inflow end formed by intersections of two or more struts, and junctions disposed between the apices and the outflow end and formed by intersections of two or more struts. The apices are circumferentially offset from the junctions. The valvular structure is positioned within and secured to the frame. The skirt is secured to the frame and includes a first edge portion and a second edge portion. The first edge portion is secured to the frame at the apices. The second edge portion is secured to the frame at the junctions. The skirt is configured to retract inwardly between the apices when the frame is moved from the radially expanded configuration to the radially collapsed configuration.
    Type: Application
    Filed: June 30, 2021
    Publication date: October 21, 2021
    Applicant: Edwards Lifesciences Corporation
    Inventors: Diana Nguyen-Thien-Nhon, Timothy A. Geiser, Larry L. Wood, Dinesh L. Sirimanne, Son V. Nguyen, Tamir S. Levi, Nikolay Gurovich, Michael Bukin
  • Patent number: 11076953
    Abstract: Systems, dies, and methods are provided for processing pericardial tissue. The method includes positioning a die-cut assembly over the pericardial tissue, the die-cut assembly including a die having a plate, a die pattern, and an opening, the die pattern attached to the plate, the opening formed in the plate to provide access to the pericardial tissue, and measuring a thickness of the tissue through the opening. The die-cut assembly may be mounted for automated vertical movement, and a platen on which the tissue is placed is capable of automated horizontal movement. Different target areas on the tissue can be assessed by measuring the thickness through the die, and when an area is deemed suitable the die pattern cuts a shape therefrom. The system is useful for cutting uniform thickness heart valve leaflets, and can be automated to speed up the process.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: August 3, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Oanh H. Nguyen, Ivan Jankovic, Diana Nguyen-Thien-Nhon, Juan C. Velez, Jon Boomgarden
  • Patent number: 11051937
    Abstract: An implantable prosthetic valve can comprise an annular frame comprising an inflow end and an outflow end and being radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration, the frame defining an axial direction extending from the inflow end to the outflow end, a leaflet structure positioned within the frame and secured thereto, and an annular outer skirt positioned around an outer surface of the frame, wherein the outer skirt comprises an inflow edge secured to the frame at a first location, an outflow edge comprising a plurality of alternating projections and notches, wherein the projections are secured to the frame at a second location, and the notches are not directly secured to the frame, an intermediate portion between the inflow edge and the outflow edge that comprises a plurality of openings.
    Type: Grant
    Filed: May 22, 2018
    Date of Patent: July 6, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Diana Nguyen-Thien-Nhon, Timothy A. Geiser, Larry L. Wood, Dinesh L. Sirimanne, Son V. Nguyen, Tamir S. Levi, Nikolay Gurovich, Michael Bukin
  • Publication number: 20200405482
    Abstract: A prosthetic heart valve comprises a radially collapsible and expandable annular frame and a leaflet structure comprising three leaflets. Each leaflet has an upper edge portion, a curved lower edge portion and two side flaps, wherein each side flap is connected to an adjacent side flap of another leaflet to form commissures of the leaflet structure, with each commissure being attached to the frame. An annular inner sleeve comprises three U-shaped portions positioned along the curved lower edge portions of the leaflets. An annular outer sleeve extends around are outer surface of the frame, wherein the outer sleeve is made of pericardium. The frame is made of Nitinol and the prosthetic valve can be radially crimped to a radially collapsed configuration inside a sheath for delivery into a patient's body and self-expand to a radially expanded configuration when released from the sheath inside the patient's body.
    Type: Application
    Filed: September 11, 2020
    Publication date: December 31, 2020
    Applicant: Edwards Lifesciences Corporation
    Inventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
  • Publication number: 20200000585
    Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
    Type: Application
    Filed: September 13, 2019
    Publication date: January 2, 2020
    Inventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
  • Publication number: 20190365530
    Abstract: A prosthetic heart valve includes an annular frame that has an inflow end and an outflow end and is radially compressible and expandable between a radially compressed configuration and a radially expanded configuration. The prosthetic heart valve further includes a leaflet structure positioned within the frame and secured thereto, and an outer sealing member mounted outside of the frame and adapted to seal against surrounding tissue when the prosthetic heart valve is implanted within a native heart valve annulus of a patient. The sealing member can include a mesh layer and pile layer comprising a plurality of pile yarns extending outwardly from the mesh layer.
    Type: Application
    Filed: August 31, 2018
    Publication date: December 5, 2019
    Inventors: Lien Huong Thi Hoang, Son V. Nguyen, Hien Tran Ngo, Vivian Tran, Russell T. Joseph, Dinesh L. Sirimanne, Kevin D. Rupp, Diana Nguyen-Thien-Nhon
  • Patent number: 10492905
    Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
    Type: Grant
    Filed: May 21, 2018
    Date of Patent: December 3, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
  • Publication number: 20190321169
    Abstract: Systems, dies, and methods are provided for processing pericardial tissue. The method includes positioning a die-cut assembly over the pericardial tissue, the die-cut assembly including a die having a plate, a die pattern, and an opening, the die pattern attached to the plate, the opening formed in the plate to provide access to the pericardial tissue, and measuring a thickness of the tissue through the opening. The die-cut assembly may be mounted for automated vertical movement, and a platen on which the tissue is placed is capable of automated horizontal movement. Different target areas on the tissue can be assessed by measuring the thickness through the die, and when an area is deemed suitable the die pattern cuts a shape therefrom. The system is useful for cutting uniform thickness heart valve leaflets, and can be automated to speed up the process.
    Type: Application
    Filed: July 1, 2019
    Publication date: October 24, 2019
    Inventors: Oanh H. Nguyen, Ivan Jankovic, Diana Nguyen-Thien-Nhon, Juan C. Velez, Jon Boomgarden
  • Patent number: 10426611
    Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: October 1, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
  • Patent number: 10413407
    Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: September 17, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
  • Patent number: 10335271
    Abstract: Systems, dies, and methods are provided for processing pericardial tissue. The method includes positioning a die-cut assembly over the pericardial tissue, the die-cut assembly including a die having a plate, a the pattern, and an opening, the die pattern attached to the plate, the opening formed in the plate to provide access to the pericardial tissue, and measuring a thickness of the tissue through the opening. The die-cut assembly may be mounted for automated vertical movement, and a platen on which the tissue is placed is capable of automated horizontal movement. Different target areas on the tissue can be assessed by measuring the thickness through the die, and when an area is deemed suitable the die pattern cuts a shape therefrom. The system is useful for cutting uniform thickness heart valve leaflets, and can be automated to speed up the process.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: July 2, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Oanh H. Nguyen, Ivan Jankovic, Diana Nguyen-Thien-Nhon, Juan C. Velez, Jon Boomgarden
  • Patent number: 10299923
    Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: May 28, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
  • Patent number: 10292817
    Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: May 21, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
  • Publication number: 20190099269
    Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
    Type: Application
    Filed: November 28, 2018
    Publication date: April 4, 2019
    Applicant: Edwards Lifesciences Corporation
    Inventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
  • Publication number: 20190099268
    Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
    Type: Application
    Filed: November 28, 2018
    Publication date: April 4, 2019
    Applicant: Edwards Lifesciences Corporation
    Inventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled