Abstract: A refillable chemical cartridge includes a flexible, foldable non-metallized bag and a two-part refillable cartridge housing. The bag includes a fitment and a septum that allow the bag to be filled with a liquid chemical to a full volume and allow the liquid chemical to be removed from the bag. The two-part refillable cartridge housing includes a top half with a latch, a bottom half with a latch receptacle, a fitment locator, and a hinge. The hinge connects the bottom and top halves forming a closable, locking housing. The cartridge housing is adapted to hold the bag in a folded position in the closed housing.