Patents by Inventor Diana Tronik

Diana Tronik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HLA-G transcripts and isoforms and their uses
    Patent number: 11655283
    Abstract: Embodiments of the disclosure pertain to the field of HLA-G molecules and their therapeutic use. The disclosure pertains to new HLA-G isoforms, that is to say new RNA transcripts and proteins deriving from the HLA-G gene, pharmaceutical composition comprising thereof, as well as primers specific of these transcripts and antibodies specific of these proteins. The disclosure further pertains to the diagnostic or therapeutic use of these molecules.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: May 23, 2023
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
    Inventors: Edgardo D. Carosella, Diana Tronik-Le Roux, Jean-Philippe Deslys, Jérôme Verine, François Desgrandchamps, Nathalie Rouas-Freiss, Joël Le Maoult
  • HLA-G TRANSCRIPTS AND ISOFORMS AND THEIR USES
    Publication number: 20200148743
    Abstract: Embodiments of the disclosure pertain to the field of HLA-G molecules and their therapeutic use. The disclosure pertains to new HLA-G isoforms, that is to say new RNA transcripts and proteins deriving from the HLA-G gene, pharmaceutical composition comprising thereof, as well as primers specific of these transcripts and antibodies specific of these proteins. The disclosure further pertains to the diagnostic or therapeutic use of these molecules.
    Type: Application
    Filed: July 24, 2018
    Publication date: May 14, 2020
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
    Inventors: Edgardo D. Carosella, Diana Tronik-Le Roux, Jean-Philippe Deslys, Jérôme Verine, François Desgrandchamps, Nathalie Rouas-Freiss, Joël Le Maoult
  • Peptides and polypeptides derived from the submaxillary gland of the rat, corresponding polyclonal and monoclonal antibodies, corresponding hybridomas and uses of these products for diagnosis, for detection or therapeutic purposes
    Publication number: 20050153374
    Abstract: The invention relates to peptides having the formula (I): X-His-Asn-Pro-Y wherein X is a rest Gln or pyro-Glu. Y is a group OH or a rest of basic aminoacid.
    Type: Application
    Filed: December 3, 2004
    Publication date: July 14, 2005
    Applicant: INSTITUT PASTEUR
    Inventors: Isabelle Rosinski-Chupin, Diana Tronik, Francois Rougeon, Nabil Seidah
  • PEPTIDES AND POLYPEPTIDES DERIVED FROM THE SUBMAXILLARY GLAND OF THE RAT CORRESPONDING POLYCLONAL AND MONOCLONAL ANTIBODIES CORRESPONDING HYBRIDOMAS AND USES OF THESE PRODUCTS FOR DIAGNOSIS FOR DETECTION OR THERAPEUTIC PURPOSES
    Patent number: 6916607
    Abstract: The present invention relates to peptides and polypeptide derived from the submaxillary gland of the rat. In particular, the present invention discloses a purified peptide of formuls: X-His-Asn-Pro-Y in which X represents a Gln or Pro-Glu residue and Y represents an OH group or residue of a basic amino acid. The present invention also relates to corresponding polyclonal and monoclonal antibodies as well as corresponding hybridomas. The products of the present invention are useful for therapeutic, diagnosis and detection purposes.
    Type: Grant
    Filed: August 31, 1999
    Date of Patent: July 12, 2005
    Assignee: Institute Pasteur
    Inventors: Isabelle Rosinski-Chupin, Diana Tronik, François Rougeon, Nabil Seidah
  • PEPTIDES AND POLYPEPTIDES DERIVED FROM THE SUBMAXILLARY GLAND OF THE RAT CORRESPONDING POLYCLONAL AND MONOCLONAL ANTIBODIES CORRESPONDING HYBRIDOMAS AND USES OF THESE PRODUCTS FOR DIAGNOSIS FOR DETECTION OR THERAPEUTIC PURPOSES
    Publication number: 20030170620
    Abstract: The present invention relates to peptides and polypeptides derived from the submaxillary gland of the rat. In particular, the present invention discloses a purified peptide of formuls: X-His-Asn-Pro-Y in which X represents a Gln or Pro-Glu residue and Y represents an OH group or residue of a basic amino acid. The present invention also relates to corresponding polyclonal and monoclonal antibodies as well as corresponding hybridomas. The products of the present invention are useful for therapeutic, diagnosis and detection purposes.
    Type: Application
    Filed: August 31, 1999
    Publication date: September 11, 2003
    Inventors: ISABELLE ROSINSKI-CHUPIN, DIANA TRONIK, FRANCOIS ROUGEON, NABIL SEIDAH
  • Antibodies directed against peptides derived from the SMR1 polypeptide
    Patent number: 6025143
    Abstract: The present invention relates to peptides and polypeptides derived from the submaxillary gland of the rat. In particular, the present invention discloses a purified peptide of formuls:X-His-Asn-Pro-Yin which X represents a Gln or Pro-Glu residue and Y represents an OH group or residue of a basic amino acid. The present invention also relates to corresponding polyclonal and monoclonal antibodies as well as corresponding hybridomas. The products of the present invention are useful for therapeutic, diagnosis and detection purposes.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 15, 2000
    Assignee: Institut Pasteur
    Inventors: Isabelle Rosinski-Chupin, Diana Tronik, Francois Rougeon, Nabil Seidah
  • Peptides and polypeptides derived from the submaxillary gland of the rat, corresponding polyclonal and monoclonal antibodies, corresponding hybridomas and uses of these products for diagnosis, for detection or therapeutic purposes
    Patent number: 5859189
    Abstract: The present invention relates to peptides and polypeptides derived from the submaxillary gland of the rat. In particular, the present invention discloses a purified peptide of formula:X--His--Asn--Pro--Yin which X represents a Gln or Pro--Glu residue and Y represents an OH group or a residue of a basic amino acid. The present invention also relates to corresponding polyclonal and monoclonal antibodies as well as corresponding hybridomas. The products of the present invention are useful for therapeutic, diagnosis and detection purposes.
    Type: Grant
    Filed: November 17, 1993
    Date of Patent: January 12, 1999
    Assignee: Institut Pasteur
    Inventors: Isabelle Rosinski-Chupin, Diana Tronik, Francois Rougeon, Nabil Seidah