Patents by Inventor Diana TRONINO

Diana TRONINO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polyethylene glycol derivatives of palmitoylethanolamide and analogous acylethanolamides
    Patent number: 9522192
    Abstract: The synthesis of a series of Polyethylene glycol conjugates (esters and carbonates) of PEA and its analogous acylethanolamides, have higher water solubility and good hydrophilic/lipophilic balance, resulting in (i) improved accumulation in tissues (particularly skin and mucosae), (ii) prolonged release, and (iii) increased bioavailability. Improvement of PEA and analogous acylethanolamides levels in the tissues—particularly in the skin and mucosae—and their prolonged release is due to the improved bioavailability of related conjugates. Conjugates are able to extend the time frame in which PEA and analogous acylethanolamides exert their pharmacological effects.
    Type: Grant
    Filed: December 11, 2013
    Date of Patent: December 20, 2016
    Assignee: EPITECH GROUP S.r.l.
    Inventors: Antonio Calignano, Giuseppe D'Agostino, Sonia Laneri, Rosaria Meli, Carmine Ostacolo, Roberto Russo, Antonia Sacchi, Diana Tronino, Francesco Della Valle, Maria Federica Della Valle, Gabriele Marcolongo
  • POLYETHYLENE GLYCOL DERIVATIVES OF PALMITOYLETHANOLAMIDE AND ANALOGOUS ACYLETHANOLAMIDES
    Publication number: 20150157733
    Abstract: The synthesis of a series of Polyethylene glycol conjugates (esters and carbonates) of PEA and its analogous acylethanolamides, have higher water solubility and good hydrophilic/lipophilic balance, resulting in (i) improved accumulation in tissues (particularly skin and mucosae), (ii) prolonged release, and (iii) increased bioavailability. Improvement of PEA and analogous acylethanolamides levels in the tissues—particularly in the skin and mucosae—and their prolonged release is due to the improved bioavailability of related conjugates. Conjugates are able to extend the time frame in which PEA and analogous acylethanolamides exert their pharmacological effects.
    Type: Application
    Filed: December 11, 2013
    Publication date: June 11, 2015
    Inventors: Antonio CALIGNANO, Giuseppe D'AGOSTINO, Sonia LANERI, Rosaria MELI, Carmine OSTACOLO, Roberto RUSSO, Antonia SACCHI, Diana TRONINO, Francesco DELLA VALLE, Maria Federica DELLA VALLE, Gabriele MARCOLONGO