Patents by Inventor Diana VARGAS-GOLD

Diana VARGAS-GOLD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multiplex nucleic acid assay methods capable of detecting closely related alleles, and reagents therefor
    Patent number: 11542547
    Abstract: This invention discloses multi-part primers for primer-dependent nucleic acid amplification methods. Also disclosed are multiplex assay methods, related reagent kits, and oligonucleotides for such methods.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: January 3, 2023
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Salvatore A. E. Marras, Diana Vargas-Gold, Sanjay Tyagi, Fred Russell Kramer
  • ASSAY METHODS AND KITS FOR DETECTING RARE SEQUENCE VARIANTS
    Publication number: 20220333183
    Abstract: This invention relates to methods for analyzing nucleic acids. The disclosure provides methods of a primer-dependent amplification and detection method that is capable of amplifying and detecting in a sample as few as ten copies of at least one rare intended target sequence in the presence of abundant closely related unintended target sequences. Also provided are reaction compositions and kits for performing the methods.
    Type: Application
    Filed: October 1, 2020
    Publication date: October 20, 2022
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Fred R. Kramer, Diana Vargas-Gold
  • Highly selective nucleic acid amplification primers
    Patent number: 11111515
    Abstract: This invention discloses multi-part primers for primer-dependent nucleic acid amplification methods. Also disclosed are primer-dependent nucleic acid amplification reactions, particularly DNA amplification reactions, reaction mixtures and reagent kits for such reactions. This invention relates to primer-dependent nucleic acid amplification reactions, particularly DNA amplification relations such as PCR, and primers, reaction mixtures and reagent kits for such reactions and assays employing same.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: September 7, 2021
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Salvatore A. Marras, Diana Vargas-Gold, Sanjay Tyagi, Fred R. Kramer
  • HIGHLY SELECTIVE NUCLEIC ACID AMPLIFICATION PRIMERS
    Publication number: 20210164009
    Abstract: This invention discloses multi-part primers for primer-dependent nucleic acid amplification methods. Also disclosed are primer-dependent nucleic acid amplification reactions, particularly DNA amplification reactions, reaction mixtures and reagent Kits for such reactions. This invention relates to primer-dependent nucleic acid amplification reactions, particularly DNA amplification relations such as PCR, and primers, reaction mixtures and reagent kits for such reactions and assays employing same.
    Type: Application
    Filed: October 23, 2020
    Publication date: June 3, 2021
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Salvatore A. Marras, Diana Vargas-Gold, Sanjay Tyagi, Fred R. Kramer
  • Highly selective nucleic acid amplification primers
    Patent number: 10815512
    Abstract: This invention discloses multi-part primers for primer-dependent nucleic amplification methods. Also disclosed are primer-dependent nucleic acid amplification reactions, particularly DNA amplification reactions, reaction mixtures and reagent kits for such reactions. This invention relates to primer-dependent nucleic acid amplification reactions, particularly DNA amplification reactions such as PCR, and primers, reaction mixtures and reagent kits for such reactions and assays employing same.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: October 27, 2020
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Salvatore Marras, Diana Vargas-Gold, Sanjay Tyagi, Fred R. Kramer
  • MULTIPLEX NUCLEIC ACID ASSAY METHODS CAPABLE OF DETECTING CLOSELY RELATED ALLELES, AND REAGENTS THEREFOR
    Publication number: 20190225999
    Abstract: This invention discloses multi-part primers for primer-dependent nucleic acid amplification methods. Also disclosed are multiplex assay methods, related reagent kits, and oligonucleotides for such methods.
    Type: Application
    Filed: April 5, 2017
    Publication date: July 25, 2019
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Salvatore A. E. MARRAS, Diana VARGAS-GOLD, Sanjay TYAGI, Fred Russell KRAMER
  • HIGHLY SELECTIVE NUCLEIC ACID AMPLIFICATION PRIMERS
    Publication number: 20180216151
    Abstract: This invention discloses multi-part primers for primer-dependent nucleic amplification methods. Also disclosed are primer-dependent nucleic acid amplification reactions, particularly DNA amplification reactions, reaction mixtures and reagent kits for such reactions. This invention relates to primer-dependent nucleic acid amplification reactions, particularly DNA amplification reactions such as PCR, and primers, reaction mixtures and reagent kits for such reactions and assays employing same.
    Type: Application
    Filed: January 22, 2018
    Publication date: August 2, 2018
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Salvatore Marras, Diana Vargas-Gold, Sanjay Tyagi, Fred R. Kramer
  • Highly selective nucleic acid amplification primers
    Patent number: 9909159
    Abstract: This invention discloses multi-part primers for primer-dependent nucleic acid amplification methods. Also disclosed are primer-dependent nucleic acid amplification reactions, particularly DNA amplification reactions, reaction mixtures and reagent kits for such reactions. This invention relates to primer-dependent nucleic acid amplification reactions, particularly DNA amplification reactions such as PCR, and primers, reaction mixtures and reagent kits for such reactions and assays employing same.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: March 6, 2018
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Salvatore Marras, Diana Vargas-Gold, Sanjay Tyagi, Fred R. Kramer
  • HIGHLY SELECTIVE NUCLEIC ACID AMPLIFICATION PRIMERS
    Publication number: 20150361475
    Abstract: This invention discloses multi-part primers for primer-dependent nucleic acid amplification methods. Also disclosed are primer-dependent nucleic acid amplification reactions, particularly DNA amplification reactions, reaction mixtures and reagent kits for such reactions. This invention relates to primer-dependent nucleic acid amplification reactions, particularly DNA amplification reactions such as PCR, and primers, reaction mixtures and reagent kits for such reactions and assays employing same.
    Type: Application
    Filed: February 7, 2014
    Publication date: December 17, 2015
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Salvatore MARRAS, Diana VARGAS-GOLD, Sanjay TYAGI, Fred R. KRAMER