Patents by Inventor Diane C. Corbo

Diane C. Corbo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spray dried erythropoietin
    Patent number: 6235710
    Abstract: The present invention provides a method for preparing stable, spray dried rhEPO and the rhEPO powder produced thereby.
    Type: Grant
    Filed: October 12, 1999
    Date of Patent: May 22, 2001
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Deepak B. Mehta, Diane C. Corbo, Kurshid Iqbal
  • Lyophilized imaging agent formulation comprising a chemotactic peptide
    Patent number: 6024938
    Abstract: A lyophilized imaging agent formulation and methods for making same are disclosed, such formulations comprise a targeting molecule such as antibody or chemotactic peptide, a linker such as diethylenetriaminepentaacetic acid (DTPA) or succinimidyl 6-hydrazinium nicotinate hydrochloride (SHNH), drying protectant such as mannitol, maltose or tricine, and excipient such as polysorbate 80, in citrate buffer. The formulations of the invention are lyophilized and may be stored stably for extended periods of time. Following reconstitution with diluent, the formulations are administered to a subject for scintigraphic imaging or therapeutic use. Also contemplated is a kit comprising a two-vial system wherein a first vial comprises a lyophilized formulation of imaging agent in the form of a lyophilized cake, and a second vial comprises a pharmaceutically acceptable carrier or diluent.
    Type: Grant
    Filed: December 24, 1997
    Date of Patent: February 15, 2000
    Assignees: Ortho Pharmaceutical Corporation, Johnson-Matthey Inc.
    Inventors: Diane C. Corbo, Mary Jean M. Link, N. Adeyinka Williams, Michelle L. Tomsho, Michael Bornstein, Howard F. Solomon, Scott K. Larsen, Robert L. Suddith
  • Spray dried erythropoietin
    Patent number: 6001800
    Abstract: A method of preparing spray dried recombinant erythropoietin (rhEPO) is disclosed. The method comprises providing an aqueous solution of rhEPO and atomizing the solution into a spray drying the spray and separating the dried rhEPO from the drying air. Also disclosed is rhEPO made by the disclosed method.
    Type: Grant
    Filed: May 15, 1998
    Date of Patent: December 14, 1999
    Assignee: Ortho Pharmaceutical Corp.
    Inventors: Deepak B. Mehta, Diane C. Corbo, Kurshid Iqbal