Patents by Inventor Diane Froen

Diane Froen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of (S)-decahydroisoquinoline-3-carboxylic acid t-butylamide
    Patent number: 5587481
    Abstract: Methods for preparing (S)-N-tert-butyl-1,2,3,4-tetrahydro-3-isoquinoline-carboxamide ("tic-c"), and converting tic-c to (S)-decahydroisoquinoline-3-carboxylic acid t-butylamide ("tic-d") are disclosed. The initial step in the formation of tic-c involves the phosgenation of a substituted tetrahydroisoquinoline to form an N-carboxy anhydride. Tic-d is used as an intermediate in the synthesis of known compounds having pharmaceutical activity.
    Type: Grant
    Filed: February 20, 1996
    Date of Patent: December 24, 1996
    Assignee: The Monsanto Company
    Inventors: David R. Allen, Scott Jenkins, Loraine Klein, Robert Erickson, Diane Froen