Abstract: An article is disclosed which comprises fibrous material which has been chemically modified such that the material's cutability using ultrasonic energy becomes facile and the material can be cut into a predetermined shape using ultrasonic energy. The article may additionally comprise fibrous material disposed between first and second fusible materials, wherein at least one of the fusible materials includes means for defining a selected line of cut, and ultrasonic energy directed through the materials along the means for defining a selected line of cut will effect cutting of the fibrous material and fusion of the fusible materials.

Abstract: A method for cutting fibrous materials using ultrasonic energy involves chemically modifying a fibrous material prior to the application of ultrasonic energy. Preferred fibrous materials include cellulose materials and its derivatives, such as, paper. Chemical modification includes oxidation or hydrolysis. Also disclosed is a test device made according to the method. The invention allows for the fusing of plastic and the simultaneous cutting of a chemically modified fibrous material along the line of fusion.

Abstract: A device and method for permitting the separation of plasma or serum from whole blood. The device comprises a matrix of hydrophilic sintered porous material to which at least one red blood cell agglutinating agent has been applied. According to a first method of using the device, a sample of whole blood is applied to a first end of the matrix and the red blood cells within the sample come in contact with the agglutinating agents present in the matrix. The blood cells agglutinate, and are entrapped in the interstices of the matrix, while substantially blood-cell-free serum or plasma accumulates near the outlet of the device. A filter means in liquid receiving relationship with the matrix functions to wick the serum or plasma from the matrix.According to an alternative aspect of the invention, a filter means in liquid receiving relationship with the outlet of the matrix functions to retain any blood cells which pass through the matrix is the filter means wicks the plasma or serum from the matrix.