Patents by Inventor Diane Liu

Diane Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of Treatment with Selective CB2 Receptor Agonists
    Publication number: 20240165109
    Abstract: Provided are methods of treatment of abdominal pain due to IBS, comprising administering to an individual in need thereof (1aS,5aS)-2-(4-Oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid ((S)-1-Hydroxymethyl-2,2-dimethyl-propyl)-amide or a pharmaceutically acceptable salt or crystal form thereof.
    Type: Application
    Filed: March 1, 2022
    Publication date: May 23, 2024
    Applicant: Arena Pharmaceuticals, Inc.
    Inventors: Fabio Cataldi, Brett Alan English, Beatriz Fioravanti Lindstrom, Charlies Chunhua Liu, Sharon Diane Skare, Stewart Alleyn Turner
  • TRICYCLIC-AMIDO-BICYCLIC PRMT5 INHIBITORS
    Publication number: 20240124442
    Abstract: Described herein are novel PRMT5 inhibitors of Formula I and pharmaceutically acceptable salts thereof, as well as the pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity and may have use in treating proliferative, metabolic and blood disorders.
    Type: Application
    Filed: February 3, 2022
    Publication date: April 18, 2024
    Applicant: AMGEN INC.
    Inventors: Albert AMEGADZIE, Diane Jennifer BEYLKIN, Shon BOOKER, Matthew Paul BOURBEAU, John R. BUTLER, Kevin Lloyd GREENMAN, Todd J. KOHN, Kexue LI, Qingyian LIU, Ana Elena MINATTI, Primali Vasundera NAVARATNE, Liping H. PETTUS, Rene RAHIMOFF, Hui-Ling WANG, Nicholas Anthony WEIRES
  • TRICYCLIC CARBOXAMIDE DERIVATIVES AS PRMT5 INHIBITORS
    Publication number: 20240101570
    Abstract: Described herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity and may have use in treating proliferative, such as cancer, metabolic and blood disorders. Compounds of Formula (I) have the following structure of Formula (I).
    Type: Application
    Filed: November 22, 2021
    Publication date: March 28, 2024
    Inventors: Albert AMEGADZIE, Diane Jennifer BEYLKIN, Shon BOOKER, Matthew Paul BOURBEAU, John R. BUTLER, Sanne Ormholt Schroder GLAD, Todd J. KOHN, Brian Alan LANMAN, Kexue LI, Qingyian LIU, Patricia LOPEZ, Francesco MANONI, Primali Vasundera NAVARATNE, Liping H. PETTUS, Rene RAHIMOFF, Nuria A. TAMAYO, Mikkel VESTERGAARD, Hui-Ling WANG, Nicholas Anthony WEIRES
  • Methods of treating systemic lupus erythematosus using a domain antibody directed against CD28
    Patent number: 11912769
    Abstract: Methods of treating autoimmune diseases, such as systemic lupus erythematosus using domain antibodies that specifically bind human CD28 are provided. The methods may comprise at least one administration cycle comprising one dose of the domain antibody. The method reduces symptoms of systemic lupus erythematosus compared to placebo.
    Type: Grant
    Filed: January 25, 2022
    Date of Patent: February 27, 2024
    Assignee: Bristol-Myers Squibb Company
    Inventors: Xavier Valencia, John P. Throup, Steven G. Nadler, Suzanne J. Suchard, Dominique Duchesne, Xiaoni Liu, Rong Shi, Diane E. Shevell, Jenny H. Xie, Marek Honczarenko
  • PROCESS OF EPITAXIAL GROWN PZT FILM AND METHOD OF MAKING A PZT DEVICE
    Publication number: 20240065105
    Abstract: A piezoelectric film stack is created by forming a lower electrode stack on a structured substrate. A pyrochlore lead zirconium titanate (PZT) buffer substrate layer is then formed on the lower electrode stack. A rapid thermal anneal of the PZT buffer substrate layer is then performed. Epitaxial perovskite (100) PZT film on the PZT buffer substrate layer is grown. An upper electrode stack is formed on the perovskite (100) PZT film.
    Type: Application
    Filed: August 17, 2022
    Publication date: February 22, 2024
    Inventors: Youming Li, Diane Liu, Darren Imai