Abstract: A system for detecting Denial-of-Service (DoS) attacks on one or more user profiles collects a number of invalid sign-on attempts on the one or more user profiles during every time interval. The system determines a number of invalid sign-on attempts on every user profile since the start of the first time interval. The system detects a first DoS attack on a particular user profile if a first number of invalid sign-on attempts on the particular user profile exceeds a single-user profile. The system detects a second DoS attack on multiple user profiles during the first time interval if the increase in the total number of invalid sign-on attempts since the last time interval exceeds a scan-level threshold number. The system detects a third DoS attack on multiple user profiles if the total number of invalid sign-on attempts detected during combined time intervals exceeds a third threshold number.

Abstract: A rear flapper, and a semi-rigid front bar to secure the device against the gum and broken root comprises a replacement tooth with a semi-rigid retention bar. Acrylic thermal beads, which are conventionally used for the creation of dental prosthetics, provide the material for the front bar. The replacement tooth is preferably provided in a variety of sizes and models to replace incisors, canines, or molars, and in a basic ivory color as well as gold and silver.

Abstract: A micro sample tube is disclosed which is of a standard size on the exterior, but which has a reduced internal volume. A slope of an inner wall of the sample tube is a second order or higher curve, and is preferably a circle. Dead volume is reduced, and standard barcode labels can be used, due to the restricted internal dimensions and standard external dimensions. The curved inner wall of the sample tube, and an internal length of the sample tube which is the same as a conventional tube, reduces the likelihood of a sample probe of an automated analyzer impacting on an inner surface of the sample tube and potentially gouging the tube and/or damaging the automated probe. In a preferred embodiment, fins extend around said tube for reduced weight and improved heat transfer of the micro sample tube.

Abstract: A chimeric toxin comprising protein fragments joined together by peptide bonds, the chimeric toxin comprising, in sequential order, beginning at the amino terminal end of the chimeric toxin,(a) the enzymatically active Fragment A of diphtheria toxin,(b) a first fragment including the cleavage domain 1.sub.1 adjacent the Fragment A of diphtheria toxin,(c) a second fragment comprising at least a portion of the hydrophobic transmembrane region of Fragment B of diphtheria toxin, the second fragment having a deletion of at least 50 diphtheria toxin amino acid residues, the deletion being C-terminal to the portion of the transmembrane region, and the second fragment not including domain 1.sub.

Abstract: A chimeric toxin comprising protein fragments joined together by peptide bonds, the chimeric toxin comprising, in sequential order, beginning at the amino terminal end of the chimeric toxin,(a) the enzymatically active Fragment A of diphtheria toxin,(b) a first fragment including the cleavage domain 1.sub.1 adjacent the Fragment A of diphtheria toxin,(c) a second fragment comprising at least a portion of the hydrophobic transmembrane region of Fragment B of diphtheria toxin, the second fragment having a deletion of at least 50 diphtheria toxin amino acid residues, the deletion being C-terminal to the portion of the transmembrane region, and the second fragment not including domain 1.sub.

Abstract: A chimeric diptheria toxin comprising protein fragments joined together by peptide bonds.