Patents by Inventor Dianna C. Green

Dianna C. Green has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4956459
    Abstract: Compounds of the formula: ##STR1## wherein each of R.sub.1 and R.sub.2 is independently selected from the group consisting of halogen, hydroxy, or mono carboxylic acid or R.sub.1 and R.sub.2 together is a multifunctional carboxylic acid residue which forms a ring with the platinum atom through two oxygens of said multifunctional carboxylic acid; R.sub.3 is a deoxy mono or disaccharide or a derivative thereof; and R.sub.4 is selected from the group consisting of hydrogen, C.sub.1-4 -alkyl, phenyl, benzyl, substituted phenyl or substituted benzyl, wherein substituents are selected from the group consisting of halogen, nitro, C.sub.1-2 -alkoxy, carboxy, carbony ester or phenyl or a pharmaceutically acceptable salt thereof are disclosed. Compositions containing these compounds and methods using these compounds are also discussed.
    Type: Grant
    Filed: January 14, 1988
    Date of Patent: September 11, 1990
    Assignee: Georgetown University
    Inventors: Abdolhossen Talebian, Dianna C. Green, Charles F. Hammer, Philip S. Schein
  • Patent number: 4946954
    Abstract: Platinum compounds useful in the treatment of cancer are disclosed. Compositions containing these compounds and methods of using the same are also discussed. Compounds having the formula ##STR1## wherein n is 0 or 1 and when n is 1 R.sub.1 is H or C.sub.1 -C.sub.4 alkyl, R is non-substituted higher alkyl or mono or disaccharide or a derivative of a mono or disaccharide,when n is O, R.sub.1 is H or C.sub.1 -C.sub.4 alkyl, R is H, halogen, non-substituted C.sub.1 -.sub.20 alkyl, aryl, arlalkyloxy, mono or disaccharide, or a derivative of a mono or disaccharide,and R.sub.2 and R.sub.3 are selected from the group consisting of hydrogen, C.sub.1.sup.-4 alkyl or R.sub.2 and R.sub.3 or R.sub.2 and R.sub.3 together are linked to adjacent carbon atoms on a four, five or six membered ring structure, or R.sub.2 and R.sub.3 together form a fused or bicyclic ring with adjacent carbon atoms, or R.sub.2 and R.sub.3 together are a substituted or unsubstituted C.sub.1-5 alkylene group; with the proviso that R and R.sub.
    Type: Grant
    Filed: January 26, 1989
    Date of Patent: August 7, 1990
    Assignee: Georgetown University
    Inventors: Abdolhossen Talebian, Dianna C. Green, Philip S. Schein
  • Patent number: 4895936
    Abstract: Platinum compounds useful in the treatment of cancer are disclosed. Compositions containing these compounds and methods of using the same are also discussed. The compound have the formula: ##STR1## wherein n is 0 or 1, R.sub.1 is selected from the group consisting of hydrogen, a mono or disaccharide or a derivative thereof linked to the nitrogen atom by a --NHCO-amide moiety, an --NHCS-- thioamide moeity or a --CO-- carbonylmoiety, R' is selected from the group consisting of hydrogen and C.sub.1-4 alkyl, and R.sub.2 and R.sub.3 are selected from the group consisting of hydrogen, C.sub.1-4 alkyl or R.sub.2 and R.sub.3 or R.sub.2 and R.sub.3 together are linked to adjacent carbon atoms on a four, five or six membered ring structure, or R.sub.2 and R.sub.3 together form a fused or bicyclic ring with adjacent carbon atoms; with the proviso that R' and R.sub.1 cannot both be hydrogen when n=o,or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: January 14, 1988
    Date of Patent: January 23, 1990
    Assignee: Georgetown University
    Inventors: Abdolhossen Talebian, Dianna C. Green, Philip S. Schein
  • Patent number: 4895935
    Abstract: Platinum compounds of the formulae: ##STR1## are disclosed. Compositions containing these compounds and methods of using the same in the treatment of tumors are also discussed.
    Type: Grant
    Filed: January 14, 1988
    Date of Patent: January 23, 1990
    Assignee: Georgetown University
    Inventors: Abdolhossen Talebian, Dianna C. Green, Charles F. Hammer, Philip S. Schein