Patents by Inventor Dianne D. Zdankiewicz

Dianne D. Zdankiewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240100200
    Abstract: The present invention is generally directed towards compositions comprising ascorbic acid or ascorbate salt and an imaging agent, and related methods. In some embodiments, the imaging agent comprises pyridaben or a pyridaben analog attached to an imaging moiety.
    Type: Application
    Filed: July 21, 2023
    Publication date: March 28, 2024
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: James F. Castner, Dianne D. Zdankiewicz, James E. Anderson
  • Publication number: 20210187131
    Abstract: The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located.
    Type: Application
    Filed: October 5, 2020
    Publication date: June 24, 2021
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: James F. Castner, Enrico Mongeau, Dianne D. Zdankiewicz, Robert W. Siegler, Richard R. Cesati
  • Patent number: 10842892
    Abstract: The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: November 24, 2020
    Assignee: Lantheus Medical Imaging, Inc.
    Inventors: James F. Castner, Enrico Mongeau, Dianne D. Zdankiewicz, Robert W. Siegler, Richard R. Cesati
  • Publication number: 20200222562
    Abstract: Radiopharmaceutical compositions, and related methods, useful for medical imaging are provided. The radiopharmaceutical compositions include one or more radiopharmaceutical compounds, together with a stabilizer comprising ascorbic acid, wherein the pH of said composition is within the range of about 3.5-5.5.
    Type: Application
    Filed: August 26, 2019
    Publication date: July 16, 2020
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: James F. Castner, Dianne D. Zdankiewicz, James E. Anderson
  • Publication number: 20190365935
    Abstract: The present invention is generally directed towards compositions comprising ascorbic acid or ascorbate salt and an imaging agent, and related methods. In some embodiments, the imaging agent comprises pyridaben or a pyridaben analog attached to an imaging moiety.
    Type: Application
    Filed: December 20, 2018
    Publication date: December 5, 2019
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: James F. Castner, Dianne D. Zdankiewicz, James E. Anderson
  • Publication number: 20190290788
    Abstract: The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located.
    Type: Application
    Filed: February 21, 2018
    Publication date: September 26, 2019
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: James F. Castner, Enrico Mongeau, Dianne D. Zdankiewicz, Robert W. Siegler, Richard R. Casati
  • Patent number: 10022462
    Abstract: The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: July 17, 2018
    Assignee: Lantheus Medical Imaging, Inc.
    Inventors: Richard R. Cesati, Edward H. Cheesman, Joel Lazewatsky, Heike S. Radeke, Enrico Mongeau, Dianne D. Zdankiewicz, Marybeth Devine
  • Publication number: 20180071411
    Abstract: Radiopharmaceutical compositions, and related methods, useful for medical imaging are provided. The radiopharmaceutical compositions include one or more radiopharmaceutical compounds, together with a stabilizer comprising ascorbic acid, wherein the pH of said composition is within the range of about 3.5-5.5.
    Type: Application
    Filed: May 23, 2017
    Publication date: March 15, 2018
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: James F. Castner, Dianne D. Zdankiewicz, James E. Anderson
  • Publication number: 20170258947
    Abstract: The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located.
    Type: Application
    Filed: February 15, 2017
    Publication date: September 14, 2017
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: Richard R. Cesati, Edward H. Cheesman, Joel Lazewatsky, Heike S. Radeke, Enrico Mongeau, Dianne D. Zdankiewicz, Marybeth Devine
  • Patent number: 9687571
    Abstract: Radiopharmaceutical compositions, and related methods, useful for medical imaging are provided. The radiopharmaceutical compositions include one or more radiopharmaceutical compounds, together with a stabilizer comprising ascorbic acid, wherein the pH of said composition is within the range of about 3.5-5.5.
    Type: Grant
    Filed: April 15, 2010
    Date of Patent: June 27, 2017
    Assignee: Lantheus Medical Imaging, Inc.
    Inventors: James F. Castner, Dianne D. Zdankiewicz, James E. Anderson
  • Patent number: 9555129
    Abstract: A stable composition useful for myocardial perfusion imaging contains one or more 2-alkynyladenosine derivatives; and a solvent which is made up of water and hydroxypropyl-?-cyclodextrin.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: January 31, 2017
    Assignee: ADENOSINE THERAPEUTICS, LLC
    Inventors: Ajit B. Thakur, Dianne D. Zdankiewicz, Hsun-Wen Hsu, James F. Castner, James E. Anderson
  • Patent number: 8936777
    Abstract: The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located.
    Type: Grant
    Filed: February 8, 2011
    Date of Patent: January 20, 2015
    Assignee: Lantheus Medical Imaging, Inc.
    Inventors: Richard R. Cesati, Edward H. Cheesman, Joel Lazewatsky, Heike S. Radeke, Enrico Mongeau, Dianne D. Zdankiewicz, Marybeth Devine
  • Publication number: 20140328757
    Abstract: The present invention is generally directed towards compositions comprising ascorbic acid or ascorbate salt and an imaging agent, and related methods. In some embodiments, the imaging agent comprises pyridaben or a pyridaben analog attached to an imaging moiety.
    Type: Application
    Filed: October 21, 2011
    Publication date: November 6, 2014
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: James F. Castner, Dianne D. Zdankiewicz, James E. Anderson
  • Publication number: 20130101508
    Abstract: Radiopharmaceutical compositions, and related methods, useful for medical imaging are provided. The radiopharmaceutical compositions include one or more radiopharmaceutical compounds, together with a stabilizer comprising ascorbic acid, wherein the pH of said composition is within the range of about 3.5-5.5.
    Type: Application
    Filed: April 15, 2010
    Publication date: April 25, 2013
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: James F. Castner, Dianne D. Zdankiewicz, James E. Anderson
  • Publication number: 20130064769
    Abstract: The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located.
    Type: Application
    Filed: February 8, 2011
    Publication date: March 14, 2013
    Applicant: Lantheus Medical Imaging, Inc
    Inventors: Richard R. Cesati, Edward H. Cheesman, Joel Lazewatsky, Heike S. Radeke, James F. Castner, Enrico Mongeau, Dianne D. Zdankiewicz, Robert Wilburn Siegler, Marybeth Devine
  • Publication number: 20130004426
    Abstract: A stable composition useful for myocardial perfusion imaging contains one or more 2-alkynyladenosine derivatives; and a solvent which is made up of water and hydroxypropyl-?-cyclodextrin.
    Type: Application
    Filed: September 14, 2012
    Publication date: January 3, 2013
    Applicant: FOREST LABORATORIES HOLDINGS LTD.
    Inventors: Ajit B. Thakur, Dianne D. Zdankiewicz, Hsun-Wen Hsu, James F. Castner, James E. Anderson
  • Publication number: 20120237445
    Abstract: Radiopharmaceutical compositions, and related methods, useful for medical imaging are provided. The radiopharmaceutical compositions include one or more radiopharmaceutical compounds, together with a stabilizer comprising ascorbic acid, wherein the pH of said composition is within the range of about 3.5-5.5.
    Type: Application
    Filed: April 15, 2010
    Publication date: September 20, 2012
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: James F. Castner, Dianne D. Zdankiewicz, James E. Anderson
  • Publication number: 20080219927
    Abstract: A stable composition useful for myocardial perfusion imaging contains one or more 2-alkynyladenosine derivatives; and a solvent which is made up of water and hydroxypropyl-?-cyclodextrin.
    Type: Application
    Filed: January 16, 2008
    Publication date: September 11, 2008
    Inventors: Ajit B. Thakur, Dianne D. Zdankiewicz, Hsun-Wen Hsu, James F. Castner, James E. Anderson