Patents by Inventor Dianne Daniels

Dianne Daniels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11931569
    Abstract: A system and a method for increasing permeability of a brain barrier selected from a blood-brain barrier or a blood-cerebrospinal fluid barrier by controlled application of pulsed electric fields.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: March 19, 2024
    Assignee: TEL HASHOMER MEDICAL RESEARCH, INFRASTRUCTURE & SERVICES LTD.
    Inventors: Yael Mardor, Shirley Sharabi, Itzik Cooper, David Last, David Guez, Dianne Daniels Elmakias, Yael Bresler
  • Patent number: 11933866
    Abstract: Apparatus for operating MRI is disclosed. The apparatus comprises: a control for operating an MRI scanner to carry out an MRI scan; an input for receiving first and second MRI scans respectively at the beginning and end of a predetermined time interval post contrast administration; a subtraction map former for forming a subtraction map from the first and the second MRI scans by analyzing the scans to distinguish between a population in which contrast clearance from the tissue is slower than contrast accumulation, and a population in which clearance is faster than accumulation; and an output to provide an indication of distribution of the populations. The control is configured to carry out the first scan at least five minutes and no more than twenty minutes post contrast administration and to carry out the second scan such that the predetermined time period is at least twenty minutes.
    Type: Grant
    Filed: August 13, 2020
    Date of Patent: March 19, 2024
    Assignees: Tel Hashomer Medical Research Infrastructure and Services Ltd., Ramot at Tel-Aviv University Ltd.
    Inventors: Yael Mardor, Leor Zach, David Guez, David Last, Dianne Daniels Elmakias
  • Patent number: 11892530
    Abstract: Apparatus for operating MRI is disclosed. The apparatus comprises: a control for operating an MRI scanner to carry out an MRI scan; an input for receiving first and second MRI scans respectively at the beginning and end of a predetermined time interval post contrast administration; a subtraction map former for forming a subtraction map from the first and the second MRI scans by analyzing the scans to distinguish between a population in which contrast clearance from the tissue is slower than contrast accumulation, and a population in which clearance is faster than accumulation; and an output to provide an indication of distribution of the populations. The control is configured to carry out the first scan at least five minutes and no more than twenty minutes post contrast administration and to carry out the second scan such that the predetermined time period is at least twenty minutes.
    Type: Grant
    Filed: August 13, 2020
    Date of Patent: February 6, 2024
    Assignees: Tel HaShomer Medical Research Infrastructure and Services Ltd., Ramot at Tel-Aviv University Ltd.
    Inventors: Yael Mardor, Leor Zach, David Guez, David Last, Dianne Daniels Elmakias
  • Patent number: 10970594
    Abstract: Apparatus for analyzing brain MRI, is disclosed. The apparatus comprises an input for receiving a first and a second MRI scans at the beginning and end of a predetermined time interval post contrast administration; a subtraction map former for forming a subtraction map from said first and said second MRI scans by analyzing said scans to distinguish between two primary populations, a slow population, in which contrast clearance from the tissue is slower than contrast accumulation, and a fast population in which clearance is faster than accumulation; and an output to provide an indication of distribution of said two primary populations, wherein said predetermined time period is at least twenty minutes.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: April 6, 2021
    Assignees: Tel HaShomer Medical Research Infrastructure and Services Ltd., Ramot at Tel-Aviv University Ltd.
    Inventors: Leor Zach, David Guez, David Last, Dianne Daniels Elmakias, Yael Mardor, Shirley Sharabi, Noam Nissan, Miriam Sklair-Levy
  • Patent number: 10809323
    Abstract: Apparatus for operating MRI is disclosed. The apparatus comprises: a control for operating an MRI scanner to carry out an MRI scan; an input for receiving first and second MRI scans respectively at the beginning and end of a predetermined time interval post contrast administration; a subtraction map former for forming a subtraction map from the first and the second MRI scans by analyzing the scans to distinguish between a population in which contrast clearance from the tissue is slower than contrast accumulation, and a population in which clearance is faster than accumulation; and an output to provide an indication of distribution of the populations. The control is configured to carry out the first scan at least five minutes and no more than twenty minutes post contrast administration and to carry out the second scan such that the predetermined time period is at least twenty minutes.
    Type: Grant
    Filed: April 24, 2014
    Date of Patent: October 20, 2020
    Assignees: Tel HaShomer Medical Research Infrastructure and Services Ltd., Remot at Tel-Aviv University Ltd.
    Inventors: Yael Mardor, Leor Zach, David Guez, David Last, Dianne Daniels
  • Patent number: 10275680
    Abstract: Apparatus for analyzing brain MRI, is disclosed. The apparatus comprises an input for receiving a first and a second MRI scans at the beginning and end of a predetermined time interval post contrast administration; a subtraction map former for forming a subtraction map from said first and said second MRI scans by analyzing said scans to distinguish between two primary populations, a slow population, in which contrast clearance from the tissue is slower than contrast accumulation, and a fast population in which clearance is faster than accumulation; and an output to provide an indication of distribution of said two primary populations, wherein said predetermined time period is at least twenty minutes.
    Type: Grant
    Filed: October 18, 2012
    Date of Patent: April 30, 2019
    Assignees: Tel HaShomer Medical Research Infrastructure and Services Ltd., Ramot at Tel-Aviv University Ltd.
    Inventors: Leor Zach, David Guez, David Last, Dianne Daniels, Yael Mardor
  • Publication number: 20140270451
    Abstract: Apparatus for analyzing brain MRI, is disclosed. The apparatus comprises an input for receiving a first and a second MRI scans at the beginning and end of a predetermined time interval post contrast administration; a subtraction map former for forming a subtraction map from said first and said second MRI scans by analyzing said scans to distinguish between two primary populations, a slow population, in which contrast clearance from the tissue is slower than contrast accumulation, and a fast population in which clearance is faster than accumulation; and an output to provide an indication of distribution of said two primary populations, wherein said predetermined time period is at least twenty minutes.
    Type: Application
    Filed: October 18, 2012
    Publication date: September 18, 2014
    Applicant: Tel HaShomer Medical Research Infrastructure and Services Ltd.
    Inventors: Leor Zach, David Guez, David Last, Dianne Daniels, Yael Mardor
  • Publication number: 20080067823
    Abstract: The present invention is comprised of an elongate piece of first material having flexible qualities with a flexible strip of second, more rigid, and bendable material enclosed within the first material. The apparatus may be twist-tied around equipment for relatively easy transport.
    Type: Application
    Filed: November 19, 2007
    Publication date: March 20, 2008
    Applicant: HANDLE IT LLC
    Inventor: Dianne Daniel
  • Publication number: 20080066264
    Abstract: The present invention is comprised of an elongate piece of first material having flexible qualities with a flexible strip of second, more rigid, and bendable material enclosed within the first material. The apparatus may be twist-tied around equipment for relatively easy transport.
    Type: Application
    Filed: November 19, 2007
    Publication date: March 20, 2008
    Applicant: HANDLE IT LLC
    Inventor: Dianne Daniel
  • Publication number: 20070145758
    Abstract: An apparatus may include an elongate piece of first material having flexible qualities with a flexible strip of second, more rigid, and bendable material enclosed within the first material. The apparatus may be twist-tied around equipment for relatively easy transport.
    Type: Application
    Filed: March 6, 2007
    Publication date: June 28, 2007
    Applicant: HANDLE IT, LLC
    Inventor: Dianne Daniel
  • Publication number: 20070063524
    Abstract: The present invention is comprised of an elongate piece of first material having flexible qualities with a flexible strip of second, more rigid, and bendable material enclosed within the first material. The apparatus may be twist-tied around equipment for relatively easy transport.
    Type: Application
    Filed: October 3, 2006
    Publication date: March 22, 2007
    Inventor: Dianne Daniel