Patents by Inventor Dianne Grail

Dianne Grail has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treatment of pulmonary disease using GM-CSF
    Patent number: 6019965
    Abstract: Methods of treatment of pulmonary disease, e.g., alveolar proteinosis, by treating a subject with an effective amount of GM-CSF.
    Type: Grant
    Filed: March 20, 1998
    Date of Patent: February 1, 2000
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Ashley Roger Dunn, Edouard Guy Stanley, Graham John Lieschke, Dianne Grail, Kerry J. Fowler
  • Animals with targeted gene disruption
    Patent number: 5777193
    Abstract: The invention provides transgenic non-human animals in which genes encoding colony-stimulating factors have been specifically disrupted, so that the animals do not express the respective factors. In specific embodiments the invention provides mice in which expression of GM-CSF, G-CSF and/or CSF-1 is disrupted. These animals do not produce any bioactive CSF of the respective type. They are useful as models for a variety of conditions, and particularly for testing of therapeutic methods.
    Type: Grant
    Filed: October 24, 1994
    Date of Patent: July 7, 1998
    Assignee: Ludwig Institute For Cancer Research
    Inventors: Ashley Roger Dunn, Edouard Guy Stanley, Graham John Lieschke, Dianne Grail, Kerry J. Fowler