Abstract: Methods and devices are disclosed for microarray analysis. In one embodiment a method is disclosed for processing a non-standard size slide having an array of chemical compounds attached to a surface of the slide. A sample is exposed to the surface of the non-standard size slide wherein components in the sample bind to the chemical compounds on the surface of the slide. The sample and the slide are incubated under conditions for carrying out the binding reactions, and the surface of the non-standard size slide is examined for the results of the binding reactions. Prior to the exposing step or the incubating step or the examining step, the non-standard size slide is placed into a slide holder comprising a slide-holding section a slide-holding section adapted to dispose the non-standard size slide to a processing instrument in a manner similar to that for a standard size slide. The non-standard size slide may also include an identifier such as a bar code.

Abstract: Methods and devices are disclosed for microarray analysis. In one embodiment a method is disclosed for processing a non-standard size slide having an array of chemical compounds attached to a surface of the slide. A sample is exposed to the surface of the non-standard size slide wherein components in the sample bind to the chemical compounds on the surface of the slide. The sample and the slide are incubated under conditions for carrying out the binding reactions, and the surface of the non-standard size slide is examined for the results of the binding reactions. Prior to the exposing step or the incubating step or the examining step, the non-standard size slide is placed into a slide holder comprising a slide-holding section a slide-holding section adapted to dispose the non-standard size slide to a processing instrument in a manner similar to that for a standard size slide. The non-standard size slide may also include an identifier such as a bar code.

Abstract: A nucleic acid array is provided, as well as methods of using the same. In certain embodiments, the nucleic acid array comprises: a) a substrate; and b) an array of features on a surface of the substrate, where the features comprise interfering RNA molecules that are linked to the surface of the substrate by a cleavable linker.

Abstract: A comparative genome hybridization method is provided. In certain embodiments, the method comprises: a) contacting a first array of surface-bound nucleic acid probes with: i) a first labeled population of target nucleic acids from a genome of an organelle of a first cell; and ii) a second labeled population of target nucleic acids from a genome of an organelle of a second cell; and b) detecting binding between said surface-bound nucleic acid probes and the first and second labeled populations of target nucleic acids. Compositions for use in the subject methods are also provided.

Abstract: A spectrophotometer used to analyzing a sample. The spectrophotometer comprises a light source and a detector. An optical assembly defines at least one light path, the light path arranged to carry light from the light source through a sample, and received by the detector, wherein a pathlength of the light through the sample is varied by adjusting an angle of incidence of the light through the sample.

Abstract: A sample cell for retaining a fluid sample comprising a handle and parallel plates. The parallel plates are coupled to the handle and are spaced at a distance thereby defining a cavity which is open on at least three sides. The distance between the plates allows capillary action to draw and retain a fluid sample in the cavity. Methods of using the sample cell are also disclosed.

Abstract: A sample cell for retaining a fluid sample comprising a handle and parallel plates. The parallel plates are coupled to the handle and are spaced at a distance thereby defining a cavity which is open on at least three sides. The distance between the plates allows capillary action to draw and retain a fluid sample in the cavity. Methods of using the sample cell are also disclosed.

Abstract: Methods and devices are disclosed for microarray analysis. In one embodiment a method is disclosed for processing a non-standard size slide having an array of chemical compounds attached to a surface of the slide. A sample is exposed to the surface of the non-standard size slide wherein components in the sample bind to the chemical compounds on the surface of the slide. The sample and the slide are incubated under conditions for carrying out the binding reactions, and the surface of the non-standard size slide is examined for the results of the binding reactions. Prior to the exposing step or the incubating step or the examining step, the non-standard size slide is placed into a slide holder comprising a slide-holding section a slide-holding section adapted to dispose the non-standard size slide to a processing instrument in a manner similar to that for a standard size slide. The non-standard size slide may also include an identifier such as a bar code.