Patents by Inventor Dianne S. Sako

Dianne S. Sako has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel P-Selectin Ligand Protein
    Publication number: 20080280327
    Abstract: A novel P-selectin ligand glycoprotein is disclosed, comprising the amino acid sequence set forth in SEQ ID NO:2 or by the amino acid sequence set forth in SEQ ID NO:4. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin- and E-selectin-mediated intercellular adhesion are also disclosed.
    Type: Application
    Filed: July 3, 2008
    Publication date: November 13, 2008
    Inventors: Glenn R. Larsen, Dianne S. Sako, Xiao-Jia Chang, Geertruida M. Veldman, Dale Cumming, Ravindra Kumar, Gray Shaw
  • Platelet glycoprotein Ib? fusion polypeptides and methods of use thereof
    Patent number: 7049128
    Abstract: The present invention provides compositions and methods for treating or preventing vascular-associated disorders.
    Type: Grant
    Filed: March 6, 2003
    Date of Patent: May 23, 2006
    Assignee: Genetics Institute LLC
    Inventors: Gray D. Shaw, Dianne S. Sako, Ravindra Kumar, Francis Sullivan, Tom McDonagh
  • Platlet glycoprotein IB? fusion polypeptides and methods of use thereof
    Patent number: 6991796
    Abstract: The present invention provides compositions and methods for treating or preventing vascular-associated disorders.
    Type: Grant
    Filed: February 6, 2002
    Date of Patent: January 31, 2006
    Assignee: Genetics Institute LLC
    Inventors: Gray D. Shaw, Dianne S. Sako, Ravindra Kumar, Francis Sullivan, Tom McDonagh
  • Platlet glycoprotein IB alpha fusion polypeptides and methods of use thereof
    Publication number: 20030232047
    Abstract: The present invention provides compositions and methods for treating or preventing vascular-associated disorders.
    Type: Application
    Filed: March 6, 2003
    Publication date: December 18, 2003
    Inventors: Gray D. Shaw, Dianne S. Sako, Ravindra Kumar, Francis Sullivan, Tom McDonagh
  • Platlet glycoprotein Ib alpha fusion polypeptides and methods of use thereof
    Publication number: 20030091576
    Abstract: The present invention provides compositions and methods for treating or preventing vascular-associated disorders.
    Type: Application
    Filed: February 6, 2002
    Publication date: May 15, 2003
    Inventors: Gray D. Shaw, Dianne S. Sako, Ravindra Kumar, Francis Sullivan, Tom McDonagh
  • Novel P-selectin ligand protein
    Publication number: 20030018181
    Abstract: A novel P-selectin ligand glycoprotein is disclosed, comprising the amino acid sequence set forth in SEQ ID NO:2 or by the amino acid sequence set forth in SEQ ID NO:4. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin- and E-selectin-mediated intercellular adhesion are also disclosed.
    Type: Application
    Filed: August 21, 2001
    Publication date: January 23, 2003
    Applicant: Genetics Institute, Inc.
    Inventors: Glenn R. Larsen, Dianne S. Sako, Xiao-Jia Chang, Geertruida M. Veldman, Dale Cumming, Ravindra Kumar, Gray Shaw
  • Fusions of P-selectin ligand protein and polynucleotides encoding same
    Patent number: 6277975
    Abstract: Fusions proteins comprising P-selectin ligand proteins are disclosed, including fusions with immunoglobulins, BMPs, AGP and IL-11. Polynucleotides encoding such fusions are also disclosed.
    Type: Grant
    Filed: August 30, 1996
    Date of Patent: August 21, 2001
    Assignee: Genetics Institute, Inc.
    Inventors: Glenn R. Larsen, Dianne S. Sako, Xiao-Jia Chang, Geertruida M. Veldman, Dale Cumming, Ravindra Kumar, Gray Shaw
  • Nucleic acid encoding a novel P-selectin ligand protein
    Patent number: 5843707
    Abstract: A novel P-selectin ligand glycoprotein is disclosed, comprising the amino acid sequence set forth in SEQ ID NO:2 or by the amino acid sequence set forth in SEQ ID NO:4. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin- and E-selectin-mediated intercellular adhesion are also disclosed.
    Type: Grant
    Filed: April 25, 1995
    Date of Patent: December 1, 1998
    Assignee: Genetics Institute, Inc.
    Inventors: Glenn R. Larsen, Dianne S. Sako, Xiao-Jia Chang, Geertruida M. Veldman, Dale Cumming, Ravindra Kumar, Gray Shaw
  • Method of inhibiting P-selectin ligand activity
    Patent number: 5840679
    Abstract: A novel P-selectin ligand glycoprotein is disclosed, comprising the amino acid sequence set forth in SEQ ID NO:2 or by the amino acid sequence set forth in SEQ ID NO:4. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin- and E-selectin-mediated intercellular adhesion are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 24, 1998
    Assignee: Genetics Institute, Inc.
    Inventors: Glenn R. Larsen, Dianne S. Sako, Xiao-Jia Chang, Geertruida M. Veldman, Dale Cumming, Ravindra Kumar, Gray Shaw, Ray Camphausen
  • P-selectin ligand protein
    Patent number: 5827817
    Abstract: A novel P-selectin ligand glycoprotein is disclosed, comprising the amino acid sequence set forth in SEQ ID NO:2 or by the amino acid sequence set forth in SEQ ID NO:4. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin- and E-selectin-mediated intercellular adhesion are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 27, 1998
    Assignee: Genetics Institute, Inc.
    Inventors: Glenn R. Larsen, Dianne S. Sako, Xiao-Jia Chang, Geertruida M. Veldman, Dale Cumming, Ravindra Kumar, Gray Shaw, Ray Camphausen