Patents by Inventor Dianne Stewart Williams

Dianne Stewart Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid encoding a poly-(ADP) ribose polymerase enzyme and uses thereof
    Patent number: 7402665
    Abstract: Poly(ADP)-ribose polymerase (PARP) becomes activated at sites of DNA damage and is thought to promote repair by modifying local chromatin proteins and transcription factors. Disclosed is an isoform of PARP, PARP-e, which lacks enzymatic function and which is encoded by a gene having a novel structure. Also disclosed are methods of modulating chromatin structure resulting in modulation of gene activation, gene repression and chromatin condensation and decondensation.
    Type: Grant
    Filed: July 31, 2003
    Date of Patent: July 22, 2008
    Assignee: Carnegie Institution of Washington
    Inventors: Allan C. Spradling, Dianne Stewart Williams, Alexei V. Tulin
  • Poly-(ADP) ribose polymerase enzyme and uses thereof
    Publication number: 20040127444
    Abstract: Poly(ADP)-ribose polymerase (PARP) becomes activated at sites of DNA damage and is thought to promote repair by modifying local chromatin proteins and transcription factors. Disclosed is an isoform of PARP, PARP-e, which lacks enzymatic function and which is encoded by a gene having a novel structure. Also disclosed are methods of modulating chromatin structure resulting in modulation of gene activation, gene repression and chromatin condensation and decondensation.
    Type: Application
    Filed: July 31, 2003
    Publication date: July 1, 2004
    Inventors: Allan C. Spradling, Dianne Stewart Williams, Alexei V. Tulin