Patents by Inventor Dick De Ridder

Dick De Ridder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYPEPTIDE EXPRESSION METHOD
    Publication number: 20150064765
    Abstract: A method for the production of a polypeptide of interest in a host cell, which method comprises: a. providing a host cell which harbours a nucleic acid encoding a polypeptide of interest, wherein the polypeptide of interest is modified so that it comprises fewer methionine and/or lysine residues than a reference polypeptide, excluding any initial methionine amino acid located at the N-terminal end of the polypeptide sequence; b. cultivating the host cell under conditions suitable for production of the polypeptide; and, optionally, c. recovering the compound of interest. The invention also relates to a modified polypeptide which comprises fewer methionine and/or lysine residues than a reference polypeptide, excluding any initial methionine amino acid located at the N-terminal end of the polypeptide sequence.
    Type: Application
    Filed: April 23, 2013
    Publication date: March 5, 2015
    Applicant: DSM IP ASSETS B.V.
    Inventors: Johannes Andries Roubos, Jan Metske Van Der Laan, Bastiaan Van Den Berg, Dick De Ridder