Patents by Inventor Dick De Zeeuw

Dick De Zeeuw has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING CKD USING PREDICTORS OF FLUID RETENTION
    Publication number: 20160128980
    Abstract: The disclosure relates to methods of treating chronic kidney disease and diabetic nephropathy using predictors of fluid retention to minimize the risk of adverse events. The methods disclosed are particularly useful in treatments involving endothelin receptor antagonists, and more particularly, atrasentan and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: November 6, 2015
    Publication date: May 12, 2016
    Inventors: Donald K. Kohan, Hiddo J. Lambers Heerspink, Dick de Zeeuw, Blai Coll, Dennis Andress
  • Pharmaceutical composition having site-specific delivery
    Patent number: 5753611
    Abstract: Use of .alpha.-hydroxy acids and poly-.alpha.-hydroxy acids as spacer between a therapeutically and/or diagnostically active compound and a soluble macromolecular carrier in pharmaceutical compositions having site-specific delivery. In one embodiment glycolic acid, L-lactic acid or tetra-L-lactic acid is used as spacer between a non-steroidal anti-inflammatory substance and a carrier of low molecular protein (LMWP).
    Type: Grant
    Filed: November 4, 1994
    Date of Patent: May 19, 1998
    Assignee: Rijksuniversiteit Groningen
    Inventors: Erik J. F. Franssen, Frits Moolenaar, Dirk K. F. Meijer, Dick De Zeeuw