Patents by Inventor Dick van der Helm

Dick van der Helm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tedanolide
    Patent number: 4743695
    Abstract: A compound having cytotoxic activity of the formula: ##STR1## and a composition comprising such compound in a suitable pharmaceutical carrier.
    Type: Grant
    Filed: January 27, 1987
    Date of Patent: May 10, 1988
    Assignee: The Board of Regents for the University of Oklahoma
    Inventors: Francis J. Schmitz, Sarath P. Gunasekera, M. Bilayet Hossain, Dick van der Helm, Gopichand Yalamanchili
  • Acanthifolic acid-new antitumor and antibiotic agent
    Patent number: 4314057
    Abstract: A purified bioactive compound of the formula: ##STR1## wherein: Q is selected from the group consisting of OY and NZ.sub.1 Z.sub.2 ;Y is selected from the group consisting of H, alkyl, hydroxyalkyl, aminoalkyl, substituted aminoalkyl, aryl and a pharmaceutically acceptable cation;Z.sub.1 and Z.sub.2 are selected from the group consisting of H, alkyl, hydroxyalkyl, aminoalkyl, substituted aminoalkyl and aryl;R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are selected from the group consisting of H, alkyl, hydroxyalkyl, aminoalkyl, substituted aminoalkyl, aryl and ##STR2## W is selected from the group consisting of H, alkyl, hydroxyalkyl, aminoalkyl, substituted aminoalkyl and aryl.
    Type: Grant
    Filed: September 15, 1980
    Date of Patent: February 2, 1982
    Assignee: Research Corporation
    Inventors: Francis J. Schmitz, Dick van der Helm, M. Bilayet Hossain, Yalamanchili Gopichand, Ravi S. Prasad
  • Acanthifolic acid--new anti-tumor and antibiotic agent
    Patent number: 4302470
    Abstract: A purified bioactive compound of the formula: ##STR1## wherein: Q is selected from the group consisting of OY and NZ.sub.1 Z.sub.2 ;Y is selected from the group consisting of H, alkyl, hydroxyalkyl, aminoalkyl, substituted aminoalkyl, aryl and a pharmaceutically acceptable cation;Z.sub.1 and Z.sub.2 are selected from the group consisting of H, alkyl, hydroxyalkyl, aminoalkyl, substituted aminoalkyl and aryl;R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are selected from the group consisting of H, alkyl, hydroxyalkyl, aminoalkyl, substituted aminoalkyl, aryl and ##STR2## and W is selected from the group consisting of H, alkyl, hydroxyalkyl, aminoalkyl, substituted aminoalkyl and aryl.
    Type: Grant
    Filed: July 21, 1980
    Date of Patent: November 24, 1981
    Assignee: Research Corporation
    Inventors: Francis J. Schmitz, Dick van der Helm, M. Bilayet Hossain, Yalamanchili Gopichand, Ravi S. Prasad