Patents by Inventor Dicky J. J. Halley

Dicky J. J. Halley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for diagnosing tuberous sclerosis by detecting mutation in the TSC-1 gene
    Patent number: 6548258
    Abstract: The present invention is directed to a tumor suppressor protein which has been designated hamartin and to the gene, TSC1, which encodes this protein. Mutations in the gene have been found to be associated with certain types of tuberous sclerosis and this has served as a basis for a diagnostic method designed to identify patients that have, or are likely to develop, symptoms associated with this disease. The introduction of the TSC1 gene and subsequent expression of hamartin into cells may be used as a means for treating tuberous sclerosis and other conditions characterized by abnormal cellular growth.
    Type: Grant
    Filed: September 12, 2001
    Date of Patent: April 15, 2003
    Assignee: Brigham and Women's Hospital
    Inventors: David J. Kwiatkowski, Julian R. Sampson, Margaret S. Povey, Marjon A. van Slegtenhorst, Dicky J. J. Halley
  • Compositions and methods based upon the tuberous sclerosis-1 (TSC1) gene and gene product
    Publication number: 20020151701
    Abstract: The present invention is directed to a tumor suppressor protein which has been designated hamartin and to the gene, TSC1, which encodes this protein. Mutations in the gene have been found to be associated with certain types of tuberous sclerosis and this has served as a basis for a diagnostic method designed to identify patients that have, or are likely to develop, symptoms associated with this disease. The introduction of the TSC1 gene and subsequent expression of hamartin into cells may be used as a means for treating tuberous sclerosis and other conditions characterized by abnormal cellular growth.
    Type: Application
    Filed: September 12, 2001
    Publication date: October 17, 2002
    Applicant: Brigham and Women's Hospital
    Inventors: David J. Kwiatkowski, Julian R. Sampson, Margaret S. Povey, Marjon A. van Slegtenhorst, Dicky J.J. Halley
  • Compositions and methods based upon the tuberous sclerosis-1 (TSC1) gene and gene product
    Patent number: 6326483
    Abstract: The present invention is directed to a tumor suppressor protein which has been designated hamartin and to the gene, TSC1, which encodes this protein. Mutations in the gene have been found to be associated with certain types of tuberous sclerosis and this has served as a basis for a diagnostic method designed to identify patients that have, or are likely to develop, symptoms associated with this disease. The introduction of the TSC1 gene and subsequent expression of hamartin into cells may be used as a means for treating tuberous sclerosis and other conditions characterized by abnormal cellular growth.
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: December 4, 2001
    Assignee: Brigham and Women's Hospital
    Inventors: David J. Kwiatkowski, Julian R. Sampson, Margaret S. Povey, Marjon A. van Slegtenhorst, Dicky J. J. Halley