Patents by Inventor Didar ASIK

Didar ASIK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS FOR USE AS IRON(III) MRI CONTRAST AGENTS
    Publication number: 20220259244
    Abstract: Provided are macrocyclic compounds and compounds with two or more macrocyclic groups, iron coordinated macrocyclic compounds, and iron coordinated compounds with two or more macrocyclic groups. The iron is high-spin iron(III). The iron coordinated compounds may exhibit a negative redox potential (e.g., relative to a normal hydrogen electrode at a biologically relevant pH, for example, a pH of 6.5-7.5). The compounds can be used as MRI contrast agents.
    Type: Application
    Filed: February 28, 2022
    Publication date: August 18, 2022
    Inventors: Janet R. MORROW, Eric M. SNYDER, Didar ASIK
  • Compounds for use as iron (III) MRI contrast agents containing anionic pendents and ancillary groups
    Patent number: 11344635
    Abstract: Macrocyclic complexes and macrocyclic compounds. The macrocyclic complexes or macrocyclic compounds have a TACN moiety with one or more amine group(s) or a O- or S-substituted TACN moiety. The macrocyclic complexes have a high-spin Fe(III) atom coordinated to the TACN moiety. The macrocyclic complexes can be used in imaging methods.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: May 31, 2022
    Assignee: The Research Foundation for the State University of New York
    Inventors: Janet R. Morrow, Zuiru Lin, Didar Asik, Eric M. Snyder, Elizabeth A. Kras
  • Compounds for use as iron(III) MRI contrast agents
    Patent number: 11261208
    Abstract: Provided are macrocyclic compounds and compounds with two or more macrocyclic groups, iron coordinated macrocyclic compounds, and iron coordinated compounds with two or more macrocyclic groups. The iron is high-spin iron(III). The iron coordinated compounds may exhibit a negative redox potential (e.g., relative to a normal hydrogen electrode at a biologically relevant pH, for example, a pH of 6.5-7.5). The compounds can be used as MRI contrast agents.
    Type: Grant
    Filed: May 21, 2018
    Date of Patent: March 1, 2022
    Assignee: The Research Foundation for The State University of New York
    Inventors: Janet R. Morrow, Eric M. Snyder, Didar Asik
  • COMPOUNDS FOR USE AS IRON (III) MRI CONTRAST AGENTS CONTAINING ANIONIC PENDENTS AND ANCILLARY GROUPS
    Publication number: 20210260222
    Abstract: Macrocyclic complexes and macrocyclic compounds. The macrocyclic complexes or macrocyclic compounds have a TACN moiety with one or more amine group(s) or a O- or S-substituted TACN moiety. The macrocyclic complexes have a high-spin Fe(III) atom coordinated to the TACN moiety. The macrocyclic complexes can be used in imaging methods.
    Type: Application
    Filed: November 18, 2019
    Publication date: August 26, 2021
    Inventors: Janet R. MORROW, Zuiru LIN, Didar ASIK, Eric M. SNYDER, Elizabeth A. KRAS
  • COMPOUNDS FOR USE AS IRON(III) MRI CONTRAST AGENTS
    Publication number: 20200079806
    Abstract: Provided are macrocyclic compounds and compounds with two or more macrocyclic groups, iron coordinated macro-cyclic compounds, and iron coordinated compounds with two or more macrocyclic groups. The iron is high-spin iron(III). The iron coordinated compounds may exhibit a negative redox potential (e.g., relative to a normal hydrogen electrode at a biologically relevant pH, for example, a pH of 6.5-7.5). The compounds can be used as MRI contrast agents.
    Type: Application
    Filed: May 21, 2018
    Publication date: March 12, 2020
    Inventors: Janet R. MORROW, Eric M. SNYDER, Didar ASIK