Abstract: The disclosure pertains to a non-invasive method and system for detecting and evaluating neural electrophysiological sources by exploring a multiplicity of points belonging to a zone of interest. The non-invasive techniques pose problems as to the instability of the estimation in relation to the position of the measurement points and errors of geometrical registration with complementary anatomical examinations, this possibly generating significant errors. The present disclosure is aimed at proposing a non-invasive method and system for detecting and evaluating profound neural electrophysiological activity which is both fast, complete and accurate.