Patents by Inventor Didier Bouvy

Didier Bouvy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of amino acid derivatives
    Patent number: 8969620
    Abstract: The present invention relates to a process of manufacture of compounds of formula (B) wherein R1, R2 and R3 are as defined for compounds of formula (A), which process comprises hydrogenation of compounds of general formula (A). In particular, the present invention relates to an improved process for the manufacture of Lacosamide (LCM), (R)-2-acetamido-N-benzyl-3-methoxypropion-amide (B1), which is useful as an anticonvulsive drug.
    Type: Grant
    Filed: September 29, 2011
    Date of Patent: March 3, 2015
    Assignee: UCB Pharma GmbH
    Inventors: Alain Merschaert, Didier Bouvy, David Vasselin, Nicolas Carly
  • Process for the preparation of amino acid derivatives
    Patent number: 8946476
    Abstract: The present patent application relates to an alternative process for the preparation of amino derivatives. In particular, the present application relates to an improved process for the manufacture of Lacosamide (LCM), (R)-2-acetamido-N-benzyl-3-methoxypropion-amide, which is useful as an anticonvulsive drug. In a particular aspect, the present invention relates to a process of manufacture of optically enriched (R)-2-acetamido-N-benzyl-3-methoxypropion-amide (I) comprising resolution of 2-acetamido-N-benzyl-3-methoxypropion-amide (II).
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: February 3, 2015
    Assignee: UCB Pharma GmbH
    Inventors: Didier Bouvy, Alain Merschaert, Véronique Pinilla, Joerg Hamann, Ralf Kanzler, Antoine Thomas
  • PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES
    Publication number: 20130190533
    Abstract: The present invention relates to a process of manufacture of compounds of formula (B) wherein R1, R2 and R3 are as defined for compounds of formula (A), which process comprises hydrogenation of compounds of general formula (A). In particular, the present invention relates to an improved process for the manufacture of Lacosamide (LCM), (R)-2-acetamido-N-benzyl-3-methoxypropion-amide (B1), which is useful as an anticonvulsive drug.
    Type: Application
    Filed: September 29, 2011
    Publication date: July 25, 2013
    Applicant: UCB PHARMA GMBH
    Inventors: Alain Merschaert, Didier Bouvy, David Vasselin, Nicolas Carly
  • Process for the preparation of 2-oxo-1-pyrrolidine derivatives
    Patent number: 8338621
    Abstract: The present invention relates to alternative processes for the preparation of 2-oxo-1-pyrrolidine derivatives of formula (I) Particularly, the present invention relates to alternative processes for the synthesis of levetiracetam, brivaracetam and seletracetam.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: December 25, 2012
    Assignee: UCB S.A.
    Inventors: John Surtees, Didier Bouvy, Antoine Thomas, Yves Combret, Michael Frank, Gunther Schmidt, Guy Duchene
  • Novel Process for the Preparation of Amino Acid Derivatives
    Publication number: 20110263899
    Abstract: The present patent application relates to an alternative process for the preparation of amino derivatives. In particular, the present application relates to an improved process for the manufacture of Lacosamide (LCM), (R)-2-acetamido-N-benzyl-3-methoxypropion-amide, which is useful as an anticonvulsive drug. In a particular aspect, the present invention relates to a process of manufacture of optically enriched (R)-2-acetamido-N-benzyl-3-methoxypropion-amide (I) comprising resolution of 2-acetamido-N-benzyl-3-methoxypropion-amide (II).
    Type: Application
    Filed: November 6, 2009
    Publication date: October 27, 2011
    Applicant: UCB PHARMA GMBH
    Inventors: Didier Bouvy, Alain Merschaert, Véronique Pinilla, Joerg Hamann, Ralf Kanzler, Antoine Thomas
  • Piperazine derivatives and their use as synthesis intermediates
    Patent number: 7381821
    Abstract: The present invention relates to new enantiomerically pure piperazine derivatives of formula (I) wherein Y represents hydroxy or a leaving group and n is 1, 2, 3, 4 or 5, and to their use as synthesis intermediates, especially for the preparation of pharmaceutically active compounds
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: June 3, 2008
    Assignee: UCB, S.A.
    Inventors: Célal Ates, Emile Cavoy, Didier Bouvy
  • PROCESS FOR THE PREPARATION OF 2-OXO-1-PYRROLIDINE DERIVATIVES
    Publication number: 20080009638
    Abstract: The present invention relates to alternative processes for the preparation of 2-oxo-1-pyrrolidine derivatives of formula (I) Particularly, the present invention relates to alternative processes for the synthesis of levetiracetam, brivaracetam and seletracetam.
    Type: Application
    Filed: December 19, 2006
    Publication date: January 10, 2008
    Applicant: UCB S.A.
    Inventors: John Surtees, Didier Bouvy, Antoine Thomas, Yves Combert, Michael Frank, Gunther Schmidt, Guy Duchene
  • Piperazine derivatives and their use as synthesis intermediates
    Publication number: 20060183903
    Abstract: The present invention relates to new enantiomerically pure piperazine derivatives of formula (I) wherein Y represents hydroxy or a leaving group and n is 1, 2, 3, 4 or 5, and to their use as synthesis intermediates, especially for the preparation of pharmaceutically active compounds.
    Type: Application
    Filed: January 20, 2004
    Publication date: August 17, 2006
    Applicant: UCB, S.A.
    Inventors: Celal Ates, Emile Cavoy, Didier Bouvy