Patents by Inventor Didier Legroux

Didier Legroux has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluorinated derivative of quinolin-2(1H)-one, method for preparing the same and use thereof as a synthesis intermediate
    Patent number: 7943769
    Abstract: The invention relates to a fluorinated derivate of quinolin-2(1H)-one (I), to a method for preparing the same, and to the use thereof as an intermediate in the synthesis of 7-fluoro-2-oxo-4-[2-[4-[thieno[3,2-c]pyridine-4-yl)piperazin-1-yl]ethyl]-1,2-dihydro-quinolin-1-acetamide. The invention also relates to the pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: June 12, 2009
    Date of Patent: May 17, 2011
    Assignee: Sanofi-Aventis
    Inventors: Didier Legroux, Veronique Moragues, Jose Ruiz-Montes, Laurent Salle
  • FLUORINATED DERIVATIVE OF QUINOLIN-2(1H)-ONE, METHOD FOR PREPARING THE SAME AND USE THEREOF AS A SYNTHESIS INTERMEDIATE
    Publication number: 20100094005
    Abstract: The invention relates to a fluorinated derivate of quinolin-2(1H)-one (I), to a method for preparing the same, and to the use thereof as an intermediate in the synthesis of 7-fluoro-2-oxo-4-[2-[4-[thieno[3,2-c]pyridine-4-yl)piperazin-1-yl]ethyl]-1,2-dihydro-quinolin-1-acetamide. The invention also relates to the pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: June 12, 2009
    Publication date: April 15, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Didier LEGROUX, Veronique MORAGUES, Jose RUIZ-MONTES, Laurent SALLE
  • Isoquinoline derivatives and their preparation
    Patent number: 4656278
    Abstract: Isoquinoline derivatives of the formula (I) ##STR1## in which R is a group selected from t-butyl and groups of the formula ##STR2## and R' is selected from methyl and ethyl, are useful in the preparation of 1(2H)-isoquinolone.
    Type: Grant
    Filed: May 14, 1985
    Date of Patent: April 7, 1987
    Assignee: Synthelabo
    Inventors: Guy Rossey, Didier Legroux
  • Process for the preparation of derivatives of quinuclidine substituted in the 3 position
    Patent number: 4546185
    Abstract: Process for the preparation of compounds of the formula: ##STR1## in which X is H, Cl, Br, I or OH, in which 3-methylene quinuclidine is reacted with an aluminum hydride, in an appropriate solvent and in the presence of a catalytic quantity of a halide of a transition metal, the molar ratio ##EQU1## being at least equal to 0.6, the product formed is reacted in situ with an ester, and then the product thus formed is reacted in situ with an electrophilic reactant which is capable of yielding an atom or group X as defined with reference to formula (I). The compounds of formula (I) can be used for the preparation of medicaments.
    Type: Grant
    Filed: August 11, 1983
    Date of Patent: October 8, 1985
    Assignee: Pharmuka Laboratoires
    Inventors: Jean-Claude Bondiou, Francoise Hodac, Didier Legroux