Patents by Inventor Didier Thomas
Didier Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10494002Abstract: Disclosed is a railway braking system including a braking device provided with a body, a single piston that can move with respect to the body to act on a brake linkage, and delimiting, together with the body, a pressure chamber supplied by a pressure medium source for placing the piston in a rest position where the linkage applies no force on a braking member of a railway vehicle, first and second seals housed between a first section of the piston and the body, and third and fourth seals housed between a second section of the piston and the body; the first and third seals being configured to form a primary sealing of the pressure chamber and the second and fourth seals being configured to form a secondary sealing of the pressure chamber.Type: GrantFiled: June 3, 2016Date of Patent: December 3, 2019Assignee: FAIVELEY TRANSPORT AMIENSInventors: Didier Thomas, Guillaume Crosnier
-
Publication number: 20180148075Abstract: Disclosed is a railway braking system including a braking device provided with a body, a single piston that can move with respect to the body to act on a brake linkage, and delimiting, together with the body, a pressure chamber supplied by a pressure medium source for placing the piston in a rest position where the linkage applies no force on a braking member of a railway vehicle, first and second seals housed between a first section of the piston and the body, and third and fourth seals housed between a second section of the piston and the body; the first and third seals being configured to form a primary sealing of the pressure chamber and the second and fourth seals being configured to form a secondary sealing of the pressure chamber.Type: ApplicationFiled: June 3, 2016Publication date: May 31, 2018Inventors: Didier THOMAS, Guillaume CROSNIER
-
Patent number: 9115151Abstract: The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.Type: GrantFiled: March 19, 2014Date of Patent: August 25, 2015Assignee: AbbVie Inc.Inventors: Dawn M. George, Maria A. Argiriadi, Martine Barth, Dominique Bonafoux, Eric C. Breinlinger, Linlin Dai, Jeremy Edmunds, Michael M. Friedman, Fabrice Guillier, Adrian D. Hobson, Dominique Potin, Didier Thomas, Jianfei Wang, Wentao Wu, Yang Zhang
-
Publication number: 20140206663Abstract: The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.Type: ApplicationFiled: March 19, 2014Publication date: July 24, 2014Inventors: Jianfei Wang, Eric C. Breinlinger, Martine Barth, Michael M. Friedman, Fabrice Guillier, Maria A. Argiriadi, Jeremy Edmunds, Dominique Potin, Adrian D. Hobson, Wentao Wu, Dominique Bonafoux, Didier Thomas, Dawn M. George, Linlin Dai, Yang Zhang
-
Patent number: 8148407Abstract: The invention relates to novel 5-thioxylose compounds, preferably derivatives of the 5-thioxylopyranose type, to the process for their preparation and to their use as active principles of drugs intended especially for the treatment or prevention of thrombosis or cardiac insufficiency.Type: GrantFiled: March 24, 2006Date of Patent: April 3, 2012Assignee: Laboratories Fournier S.A.Inventors: Véronique Barberousse, Michel Bondoux, Didier Thomas, Vincent Peyrou
-
Patent number: 8093394Abstract: The invention relates to new compounds of 5-thioxilose, preferably derivatives of the 5-thioxilopyranose type, and to a method for preparing the same and their use as the active ingredient of drugs mainly intended for treating or inhibiting thrombosis or heart failure or thromboembolic diseases.Type: GrantFiled: March 26, 2009Date of Patent: January 10, 2012Assignee: Laboratoires Fournier S.A.Inventors: Véronique Barberousse, Didier Thomas, Michel Bondoux
-
Patent number: 8013010Abstract: Compounds of 5-thioxylopyranose, preferably derivatives of the 5-thioxilopyranose type, a method for preparing such compounds, and the use of such compounds as an active ingredient in pharmaceutical compositions which are useful, in particular, for treating or inhibiting thrombosis or heart failure or thromboembolic disease states.Type: GrantFiled: March 26, 2009Date of Patent: September 6, 2011Assignee: Laboratoires Fournier S.A.Inventors: Véronique Barberousse, Didier Thomas, Michel Bondoux
-
Patent number: 7652032Abstract: 5-thioxylose compounds, especially 5-thioxylopyranose compounds, a process for their preparation, and their use for treating and/or inhibiting thromboses, especially venous thromboses.Type: GrantFiled: January 12, 2009Date of Patent: January 26, 2010Assignee: Laboratoires Fournier S.A.Inventors: Didier Thomas, Michel Bondoux, Véronique Barberousse, Vincent Peyrou
-
Publication number: 20090186840Abstract: Compounds of 5-thioxylopyranose, preferably derivatives of the 5-thioxilopyranose type, a method for preparing such compounds, and the use of such compounds as an active ingredient in pharmaceutical compositions which are useful, in particular, for treating or inhibiting thrombosis or heart failure or thromboembolic disease states.Type: ApplicationFiled: March 26, 2009Publication date: July 23, 2009Applicant: Laboratoires Fournier S.AInventors: Veronique BARBEROUSSE, Didier Thomas, Michel Bondoux
-
Publication number: 20090182013Abstract: The invention relates to new compounds of 5-thioxilose, preferably derivatives of the 5-thioxilopyranose type, and to a method for preparing the same and their use as the active ingredient of drugs mainly intended for treating or inhibiting thrombosis or heart failure or thromboembolic diseases.Type: ApplicationFiled: March 26, 2009Publication date: July 16, 2009Applicant: Laboratoires Fournier S.A.Inventors: Veronique Barberousse, Didier Thomas, Michel Bondoux
-
Patent number: 7538111Abstract: The present invention concerns novel benzenesulphonamide compounds, defined by formula I. Therapeutic compositions comprising the benzenesulphonamide compounds of the invention or salts thereof and methods for producing the benzenesulphonamide compounds of the invention are also disclosed. The benzenesulphonamide compounds of the invention or salts thereof are useful for treating pain, such as hyperalgesia and major algesia.Type: GrantFiled: March 24, 2004Date of Patent: May 26, 2009Assignee: Laboratoires Fournier S.A.Inventors: Martine Barth, Michel Bondoux, Pierre Dodey, Christine Massardier, Didier Thomas, Jean-Michel Luccarini
-
Publication number: 20090118325Abstract: 5-thioxylose compounds, especially 5-thioxylopyranose compounds, a process for their preparation, and their use for treating and/or inhibiting thromboses, especially venous thromboses.Type: ApplicationFiled: January 12, 2009Publication date: May 7, 2009Applicant: LABORATOIRES FOURNIER S.A.Inventors: Didier THOMAS, Michel Bondoux, Veronique Barberousse, Vincent Peyrou
-
Publication number: 20080293768Abstract: The invention relates to novel 5-thioxylose compounds, preferably derivatives of the 5-thioxylopyranose type, to the process for their preparation and to their use as active principles of drugs intended especially for the treatment or prevention of thrombosis or cardiac insufficiency.Type: ApplicationFiled: March 24, 2006Publication date: November 27, 2008Inventors: Veronique Barberousse, Michel Bondoux, Didier Thomas, Vincent Peyrou
-
Publication number: 20060178360Abstract: The present invention concerns novel benzenesulphonamide compounds, defined by formula I and the description, their method of preparation and their use in therapy.Type: ApplicationFiled: March 24, 2004Publication date: August 10, 2006Applicant: Laboratoires Fournier S.A.Inventors: Martine Barth, Michel Bondoux, Pierre Dodey, Christine Massardier, Didier Thomas, Jean-Michel Luccarini
-
Publication number: 20060025589Abstract: The invention relates to 2-thiohydantoin compounds selected from compounds of general formula (I): in which, in particular, one of the radicals R1 and R2 comprises two aromatic rings in the structure or is the dibenzofuranyl group, R3 is a hydrogen atom, a halogen atom, a C1-C4 alkyl group, a C1-C4 alkoxy group, a hydroxyl group, a phenyl group or a benzyl group, R4 is a hydrogen atom, a halogen atom or a C1-C4 alkyl group, and their addition salts with a non-toxic acid, especially the pharmaceutically acceptable salts. It further relates to the process for their preparation, to the pharmaceutical compositions in which they are present, and to their use as pharmacologically active substances, especially in the case of the treatment of diabetes, diseases due to hyperglycemia, hypertriglyceridemia, dyslipidemia or obesity.Type: ApplicationFiled: October 3, 2003Publication date: February 2, 2006Inventors: Jean Binet, Benaissa Boubia, Evelyne Chaput, Alan Edgar, Khan Ou, Philippe Ratel, Soth Samreth, Didier Thomas
-
Patent number: 6422293Abstract: Placed in a box (1) is a ceramic shell (21) delimiting a casting space (22), the shell being surrounded by a mass of binder-free sand (23). The casting space is connected to a source (4) of liquid metal located underneath, in which are applied, in succession, a pressure (P1) bringing the liquid to the threshold of the casting space (22), a pressure (P2) slightly greater than that necessary for filling this space, and then a marked overpressure (P3); finally, the pressure is brought back down to the first value (P1). When the casting space has been filled, an underpressure is created in the space containing the mass of sand (23) in order to prevent any deformation of the shell (21) due to the overpressure (P3), at least until the formation of a metal skin against the shell and at most until the start of the reduction in the overpressure in the source (4) of liquid metal.Type: GrantFiled: November 18, 1999Date of Patent: July 23, 2002Assignee: SEVAInventors: Jean-Louis Comarteau, Christophe Liebaut, Alain Reny, Didier Thomas
-
Patent number: 4937558Abstract: A device and system for detecting the existance of fluid flow from a fluid source to a pipeline includes a cylinder with an inlet at a first end and a lateral outlet. A piston in the cylinder is moveable from a no-flow position abutting the first end in which it is maintained by a spring, to a flow position in which the piston at least partly opens the lateral outlet, by fluid flowing from the inlet to the lateral outlet. A magnetic switch detects the no-flow position of the piston, and actuates a radio transmitter to send a no-flow condition alarm. The device is used to detect interruptions in the supply of additives to oil and gas pipelines.Type: GrantFiled: March 6, 1989Date of Patent: June 26, 1990Assignee: Societe Nationale Elf Aquitaine (Production)Inventors: Alain Robinet, Didier Thomas