Abstract: A system (100) for processing medical image data regarding a clinical question uses patient data (110), medical image data (120) and clinical guidelines (170). The system has a processor subsystem (160) to determine, based on user input (140), a use case regarding the clinical question for a patient. The processor retrieves the patient data and image data regarding the use case to determine an anatomical object. Then, the processor selects an algorithm from an algorithm repository (AM) based on the determined anatomical object and executes the algorithm on the image data to provide the output data for assessing the clinical question. The processor may also use the codified clinical guidelines regarding the use case to select said algorithm. Effectively the most appropriate algorithm is executed for the specific use case.