Patents by Inventor Diederik Willem Elisabeth MOECHARS

Diederik Willem Elisabeth MOECHARS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TAU PET IMAGING LIGANDS
    Publication number: 20220024896
    Abstract: The present invention relates to novel, selective radiolabelled tau ligands which are useful for imaging and quantifying tau aggregates, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue or a subject, in vitro or in vivo, and to precursors of said compounds.
    Type: Application
    Filed: October 7, 2021
    Publication date: January 27, 2022
    Inventors: José Ignacio Andrés-Gil, Guy Maurits R. Bormans, Lieven Denis Herwig Declercq, Katleen Fierens, Joseph Elisabeth Leenaerts, Diederik Willem Elisabeth Moechars, Frederik Jan Rita Rombouts, Hartmuth Kolb, Wei Zhang
  • Tau PET imaging ligands
    Patent number: 11168068
    Abstract: The present invention relates to novel, selective radiolabelled tau ligands which are useful for imaging and quantifying tau aggregates, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue or a subject, in vitro or in vivo, and to precursors of said compounds.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: November 9, 2021
    Assignee: Janssen Pharmaceutica NV
    Inventors: José Ignacio Andrés-Gil, Guy Maurits R. Bormans, Lieven Denis Herwig Declercq, Katleen Fierens, Joseph Elisabeth Leenaerts, Diederik Willem Elisabeth Moechars, Frederik Jan Rita Rombouts, Hartmuth Kolb, Wei Zhang
  • TAU PET IMAGING LIGANDS
    Publication number: 20210283277
    Abstract: The present invention relates to novel, selective radiolabelled tau ligands which are useful for imaging and quantifying tau aggregates, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue or a subject, in vitro or in vivo, and to precursors of said compounds.
    Type: Application
    Filed: April 30, 2021
    Publication date: September 16, 2021
    Inventors: Diederik Willem Elisabeth MOECHARS, Frederik Jan Rita ROMBOUTS, Joseph Elisabeth LEENAERTS, José Ignacio ANDRéS-GIL, Katleen FIERENS, Vladimir CHUPAKHIN, Guy Mauritis R. BORMANS, Lieven Denis Herwig DECLERCQ, Hartmuth KOLB, Wei ZHANG
  • TAU PET IMAGING LIGANDS
    Publication number: 20190284165
    Abstract: The present invention relates to novel, selective radiolabelled tau ligands which are useful for imaging and quantifying tau aggregates, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue or a subject, in vitro or in vivo, and to precursors of said compounds.
    Type: Application
    Filed: July 14, 2017
    Publication date: September 19, 2019
    Inventors: Jos ANDRéS-GIL Andres-Gil, Guy Maurits R. BORMANS, Lieven Denis Herwig DECLERCQ, Katleen FIERENS, Joseph Elisabeth LEENAERTS, Diederik Willem Elisabeth MOECHARS, Frederik Jan Rita ROMBOUTS, Hartmuth KOLB, Wei ZHANG
  • TAU PET IMAGING LIGANDS
    Publication number: 20190038784
    Abstract: The present invention relates to novel, selective radiolabelled tau ligands which are useful for imaging and quantifying tau aggregates, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue or a subject, in vitro or in vivo, and to precursors of said compounds.
    Type: Application
    Filed: February 1, 2017
    Publication date: February 7, 2019
    Inventors: Diederik Willem Elisabeth MOECHARS, Frederik Jan Rita ROMBOUTS, Joseph Elisabeth LEENAERTS, José Ignacio ANDRéS-GIL, Katleen FIERENS, Vladimir CHUPAKHIN, Guy Maurits R. BORMANS, Lieven Denis Herwig DECLERCQ, Hartmuth KOLB, Wei ZHANG