Patents by Inventor Diego Borges-Rivera

Diego Borges-Rivera has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATION OF GENE EXPRESSION FOR DISEASE TREATMENT
    Publication number: 20240226328
    Abstract: Provided in the present disclosure include targeted therapeutics for regulating gene transcription at a specific locus (or loci). Such targeted therapeutics can be used as novel genomic therapeutics for treating and/or preventing a disease or disorder that is tightly associated with the locus where the gene transcription is reprogrammed using the present systems. The regulatory system comprises a macromolecular complex of transcription effector proteins that is directed to a locus using CRISPR-dCas9.
    Type: Application
    Filed: October 30, 2023
    Publication date: July 11, 2024
    Inventors: Thomas T. Tibbitts, Diego Borges-Rivera
  • MODULATION OF GENE EXPRESSION FOR DISEASE TREATMENT
    Publication number: 20240131188
    Abstract: Provided in the present disclosure include targeted therapeutics for regulating gene transcription at a specific locus (or loci). Such targeted therapeutics can be used as novel genomic therapeutics for treating and/or preventing a disease or disorder that is tightly associated with the locus where the gene transcription is reprogrammed using the present systems. The regulatory system comprises a macromolecular complex of transcription effector proteins that is directed to a locus using CRISPR-dCas9.
    Type: Application
    Filed: October 29, 2023
    Publication date: April 25, 2024
    Inventors: Thomas T. Tibbitts, Diego Borges-Rivera