Patents by Inventor Diego D'Astolfo

Diego D'Astolfo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENE-EDITING SYSTEMS FOR EDITING A CYSTIC FIBROSIS TRANSMEMBRANE REGULATOR (CFTR) GENE
    Publication number: 20210403906
    Abstract: Described herein are highly efficient gene-editing systems comprising a nuclease, a guide RNA, and/or a donor template and uses thereof for editing a cystic fibrosis transmembrane regulator (CFTR) gene either in vitro or in vivo.
    Type: Application
    Filed: June 4, 2021
    Publication date: December 30, 2021
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Marco Weinberg, Diego D'Astolfo
  • TRANSDUCTION BUFFER
    Publication number: 20180327783
    Abstract: The invention relates to transduction compounds, buffers and methods for introducing molecules into cells. The invention also relates to methods of treatment, pharmaceutical compositions and other uses of the transduction compounds and buffers. The invention also relates to modified cells obtainable by the transduction compounds, buffers and methods of the invention.
    Type: Application
    Filed: November 30, 2016
    Publication date: November 15, 2018
    Inventors: Niels Geijsen, Peng Shang, Diego D'Astolfo