Patents by Inventor Dieter Dorsch

Dieter Dorsch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carbonyl compounds
    Patent number: 7906516
    Abstract: Novel compounds of the formula (I), in which D, E, G, W, X, Y, T, R1 and R2 are as defined in Patent Claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumours.
    Type: Grant
    Filed: March 8, 2004
    Date of Patent: March 15, 2011
    Assignee: Merck Patent GmbH
    Inventors: Christos Tsaklakidis, Dieter Dorsch, Werner Mederski, Bertram Cezanne, Johannes Gleitz
  • Phenyl derivatives as factor XA inhibitors
    Patent number: 7902223
    Abstract: Novel compounds of the formula (I), in which D, W, X, Y, T and R1 are as defined in Patent Claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumors.
    Type: Grant
    Filed: July 12, 2002
    Date of Patent: March 8, 2011
    Assignee: Merck Patent GmbH
    Inventors: Dieter Dorsch, Bertram Cezanne, Christos Tsaklakidis, Werner Mederski, Johannes Gleitz, Christopher Barnes
  • Substituted 5-phenyl-3,6-dihydro-2-oxo-6H-1,3,4-thiadiazines
    Patent number: 7902186
    Abstract: Compounds of the formula (I), in which R1, R2, m, Q and B have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Grant
    Filed: October 25, 2006
    Date of Patent: March 8, 2011
    Assignee: Merck Patent GmbH
    Inventors: Oliver Schadt, Dieter Dorsch, Melanie Schultz, Andree Blaukat
  • PYRIDAZINONE DERIVATIVES
    Publication number: 20110034474
    Abstract: Compounds of the formula (I), in which R1, R2, R3, W and D have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular of Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Application
    Filed: March 24, 2009
    Publication date: February 10, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Dieter Dorsch, Oliver Schadt, Frank Stieber, Andree Blaukat
  • 1-acyldihydropyrazole derivatives
    Patent number: 7875644
    Abstract: Compounds of the formula (I), in which R1, R2, R3a, R3b, R3c and R3d have the meanings indicated in claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Grant
    Filed: July 18, 2006
    Date of Patent: January 25, 2011
    Assignee: Merck Patent GmbH
    Inventors: Dieter Dorsch, Oliver Schadt, Andree Blaukat
  • 3-aminoindazoles
    Patent number: 7872039
    Abstract: Novel 3-aminoindazoles of the formula (I) are SGK inhibitors and can be used for the treatment of SGK-induced diseases and conditions, such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonary hypertonia, cardiovascular diseases and renal diseases, generally in fibrosis and inflammatory processes of any type.
    Type: Grant
    Filed: April 4, 2005
    Date of Patent: January 18, 2011
    Assignee: Merck Patent Gesellschaft
    Inventors: Dieter Dorsch, Lars Thore Burgdorf, Rolf Gericke, Norbert Beier, Werner Mederski, Florian Lang
  • THIADIAZINONE DERIVATIVES
    Publication number: 20100311733
    Abstract: Compounds of the formula (I), in which R1, Q and Het have the meanings indicated in Claim 1), are inhibitors of tyrosine kinases, in particular of Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Application
    Filed: August 6, 2008
    Publication date: December 9, 2010
    Applicant: MERCK PATENT GESELLSCHAFT MIT ESCHRANKTER HAFTUNG
    Inventors: Oliver Schadt, Dieter Dorsch, Frank Stieber, Andree Blaukat
  • 4 (PYRROLO[2,3-C]PYRIDINE-3-YL)PYRIMIDIN-2-AMINE DERIVATIVES
    Publication number: 20100292262
    Abstract: Compounds of the formula (I), in which R1, R2, R3, R4 and R5 have the meanings indicated in Claim 1, are inhibitors of cell proliferation/cell vitality and can be employed for the treatment of tumours.
    Type: Application
    Filed: December 23, 2008
    Publication date: November 18, 2010
    Applicant: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Dieter Dorsch, Christian Sirrenberg, Thomas J.J. Mueller, Eugen Merkul
  • 2-OXO-3-BENZYLBENZOXAZOL-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS MET KINASE INHIBITORS FOR THE TREATMENT OF TUMOURS
    Publication number: 20100280030
    Abstract: Compounds of the formula (I), in which R1, R2, R3, R3?, R4, R4?, E, E?, E? and E?? have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Application
    Filed: May 8, 2008
    Publication date: November 4, 2010
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Oliver Schadt, Dieter Dorsch, Frank Stieber, Andree Blaukat
  • 2-BENZYLPYRIDAZINONE DERIVATIVES AS MET KINASE INHIBITORS
    Publication number: 20100273796
    Abstract: Compounds of the formula I in which R1, R2, R3, R4? have the meanings indicated in claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Application
    Filed: November 25, 2008
    Publication date: October 28, 2010
    Applicant: Merck Patent Gesellschaft MIT Beschrankter Haftung
    Inventors: Dieter Dorsch, Oliver Schadt, Andree Blaukat
  • 2-(HETEROCYCLYLBENZYL)PYRIDAZINONE DERIVATIVES
    Publication number: 20100261697
    Abstract: Compounds of the formula (I) in which R1, R2, R3, R4 and R5 have the meanings indicated in claim 1 are inhibitors of tyrosine kinases, in particular of met kinase and can be employed inter alia for the treatment of tumours.
    Type: Application
    Filed: July 12, 2007
    Publication date: October 14, 2010
    Inventors: Dieter Dorsch, Oliver Schadt, Andree Blaukat, Frank Stieber
  • CARBONYL COMPOUNDS
    Publication number: 20100256131
    Abstract: Novel compounds of the formula (I), in which D, E, G, W, X, Y, T, R1 and R2 are as defined in Patent Claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumours.
    Type: Application
    Filed: June 17, 2010
    Publication date: October 7, 2010
    Inventors: Christos TSAKLAKIDIS, Dieter DORSCH, Werner MEDERSKI, Bertaram CEZÁNNE, Johannes GLEITZ
  • PYRIDAZINONE DERIVATIVES
    Publication number: 20100234354
    Abstract: Compounds of the formula (I), in which R1, R2, R, R4, R4? have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Application
    Filed: April 29, 2008
    Publication date: September 16, 2010
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Dieter Dorsch, Frank Stieber, Oliver Schadt, Andree Blaukat
  • PROCESS FOR THE PREPARATION OF N-ARYLMORPHOLINONES
    Publication number: 20100210864
    Abstract: Process for the preparation of compounds of the formula (I) in which X has the meaning indicated in Patent Claim 1, and precursors thereof.
    Type: Application
    Filed: February 16, 2010
    Publication date: August 19, 2010
    Inventors: Dieter DORSCH, Bertram Cezanne, Werner Mederski, Christos Tsaklakidis, Hanns Wurziger
  • Pyrimidinyl Pyridazinone Derivatives
    Publication number: 20100197690
    Abstract: Compounds selected from the group according to Claim 1 are inhibitors of tyrosine kinases, in particular of Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Application
    Filed: July 4, 2008
    Publication date: August 5, 2010
    Applicant: MERCK PATENT GESELLSCHAFT
    Inventors: Oliver Schadt, Dieter Dorsch, Frank Stieber, Andree Blaukat
  • Acyl hydrazines as kinase inhibitors, in particular for SGK
    Patent number: 7767716
    Abstract: Novel acyl hydrazides of the formula (I), in which R1-R9 have the meanings indicated in claim 1, are SGK inhibitors and can be used for the treatment of SGK-induced diseases and complaints, such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonary hypertonia, cardiovascular diseases and renal diseases, generally in fibroses and inflammatory processes of any type.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: August 3, 2010
    Assignee: Merck Patent GmbH
    Inventors: Rolf Gericke, Dieter Dorsch, Werner Mederski, Markus Klein, Norbert Beier, Florian Lang
  • Aroylsemicarbazide derivatives against thromboembolic diseases
    Patent number: 7763611
    Abstract: Novel compounds of the formula (I) in which Het, R1, R2 and R3 have the meaning indicated in Patent claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumors.
    Type: Grant
    Filed: May 12, 2004
    Date of Patent: July 27, 2010
    Assignee: Merck Patent GmbH
    Inventors: Werner Mederski, Christos Tsaklakidis, Dieter Dorsch, Bertram Cezanne, Johannes Gleitz
  • ARYL ETHER PYRIDAZINONE DERIVATIVES
    Publication number: 20100179149
    Abstract: Compounds of the formula I, in which R1, R2, R3, R4, R5 and X have the meanings indicated in claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Application
    Filed: May 2, 2008
    Publication date: July 15, 2010
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG
    Inventors: Frank Stieber, Oliver Schadt, Dieter Dorsch, Andree Blaukat
  • PYRIDAZINONE DERIVATIVES
    Publication number: 20100179148
    Abstract: Compounds of the formula (I), in which R1, R2 and R3 have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Application
    Filed: May 2, 2008
    Publication date: July 15, 2010
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Frank Stieber, Oliver Schadt, Dieter Dorsch, Andree Blaukat
  • 4 (PYRROLOPYRIDINYL)PYRIMIDINYL-2-AMINE DERIVATIVES
    Publication number: 20100173923
    Abstract: Compounds of the formula I in which R1, R2, R3, R4 and R5 are each as defined in claim 1 are inhibitors of cell proliferation/cell vitality and can be used to treat tumors.
    Type: Application
    Filed: February 21, 2007
    Publication date: July 8, 2010
    Inventors: Dieter Dorsch, Christian Sirrenberg, Thomas Mueller