Patents by Inventor DIETER EDBAUER

DIETER EDBAUER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunogen for Preventing or Treating Familial Frontotemporal Dementia (FTD) and/or Amyotrophic Lateral Sclerosis (ALS)
    Publication number: 20220202935
    Abstract: The present invention relates to an immunogen for use in preventing or treating familial frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS) and/or amyotrophic lateral sclerosis-frontotemporal dementia (ALS-FTD) in patients with C9orf72 repeat expansion. The immunogen is comprising or consisting of a polypeptide consisting of dipeptide-repeats with a sequence selected from the group consisting of (Gly-Ala)a, (Gly-Pro)a, (Gly-Arg)a, (Pro-Ala)a and (Pro-Arg)a, wherein a is an integer of 4 to 25.
    Type: Application
    Filed: May 4, 2020
    Publication date: June 30, 2022
    Inventors: Dieter Edbauer, Qihui Zhou, Nikola Marelijic
  • Dipeptide-repeat proteins as therapeutic target in neurodegenerative diseases with hexanucleotide repeat expansion
    Patent number: 10066007
    Abstract: The present invention relates to a method of detecting a disease characterized by an expansion of genomic hexanucleotide repeats as well as polypeptides of said hexanucleotide repeats, ligands specifically binding to the polypeptides, and to methods of identifying an inhibitor preventing the expression and/or aggregation of said polypeptide.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: September 4, 2018
    Assignee: DEUTSCHES ZENTRUM FÜR NEURODEGENERATIVE ERKRANKUNGEN E.V. (DZNE)
    Inventors: Dieter Edbauer, Christian Haass, Shih-Ming Weng, Kohji Mori, Thomas Arzberger, Elisabeth Kremmer
  • DIPEPTIDE-REPEAT PROTEINS AS THERAPEUTIC TARGET IN NEURODEGENERATIVE DISEASES WITH HEXANUCLEOTIDE REPEAT EXPANSION
    Publication number: 20150361166
    Abstract: The present invention relates to a method of detecting a disease characterized by an expansion of genomic hexanucleotide repeats as well as polypeptides of said hexanucleotide repeats, ligands specifically binding to the polypeptide, methods of identifying an inhibitor preventing the expression and/or aggregation of said polypeptide.
    Type: Application
    Filed: January 22, 2014
    Publication date: December 17, 2015
    Inventors: DIETER EDBAUER, CHRISTIAN HAASS, SHIH-MING WENG, KOHJI MORI, THOMAS ARZTBERGER, ELISABETH KREMMER