Abstract: Crosslinkable silicone resins of high molecular weight are produced in a multistep process by reacting a mixture of at least two different silicone resin intermediates (A) composed of units of the formula Ra(OR1)bO(4-a-b)/2 (1), having a molecular weight Mw of 600 to 2500 to an extent such groups OR1 are reduced by at least 5% resulting alcohol is preferably removed by distillation to obtain silicone resins having a molecular weight Mw between 2500 and 10,000 g/mol, and then the silicone resins are further condensed with polyhydric alcohols in the presence of water to obtain silicone resins having a molecular weight Mw of 5000 to 50,000 g/mol.

Abstract: Crosslinkable compositions containing an alkoxy-functional polyorganosiloxane and a titanium chelate complex exhibit good moisture-curing properties and produce coatings resistant to temperature ramp extremes.

Abstract: Crosslinkable compositions containing an alkoxy-functional polyorganosiloxane and a titanium chelate complex exhibit good moisture-curing properties and produce coatings resistant to temperature ramp extremes.

Abstract: The present invention is directed to novel pyrazolo-estrien and triazolo-estrien-derivatives, pharmaceutical compositions containing them and their use in the treatment or prevention of disorders and diseases mediated by an estrogen receptor such as hot flashes, vaginal dryness, osteopenia, osteoporosis, hyperlipidemia, loss of cognitive function, degenerative brain diseases, cardiovascular diseases, cerebrovascular diseases, hormone sensitive cancers and hyperplasia (in tissues including breast, endometrium, and cervix in women and prostate in men), endometriosis, uterine fibroids, osteoarthritis; and as contraceptive agents either alone or in combination with a progestogen or progestogen antagonist. The compounds of the invention are selective estrogen receptor modulators.

Abstract: The invention relates to radioactive stents, characterized in that the stent is coated on the surface with the radioactive isotope, as well as processes for their production.

Abstract: A process for preparing ?-functionalized thiazolidines or oxazolidines, each of which are oxycarbonyl-functionalized in the 4-position, by adding a base to a reaction mixture comprising an oxycarbonyl-functionalized thiazolidine or oxazolidine and an electrophile at a temperature of greater than ?40° C.

Abstract: Preparation of ?-substituted cysteine derivatives takes place by acidic hydrolysis of thiazolidines, wherein the hydrolysis is effected in the presence of a further phase comprising an organic solvent and a vapor comprising water, acid, organic solvent and aldehyde is removed from the reaction mixture, or a vapor comprising water, acid and aldehyde is removed from the reaction mixture and the vapor or its condensate is subsequently contacted with a phase comprising an organic solvent. The process requires less hydrolysis time and allows for recycle and/or recovery of acid and by product aldehyde.

Abstract: This invention relates to the use of labeled L19 derivatives for the production of a pharmaceutical composition for detection of arteriosclerotic plaque.

Abstract: Silanes of the formula Ra1R4-a-xSiLx??(I) where each R is identical or different and is a monovalent, optionally substituted hydrocarbon radical which is free of aliphatic carbon—carbon multiple bonds and has from 1 to 18 carbon atoms per radical, R1 is an optionally substituted 2-norbornyl radical, L is a leaving group, a is 1, 2 or 3 and x is 1 or 2, with the proviso that the sum of a+x?4, are useful for protecting functional groups of organic compounds (2) which have at least one functional group having an active hydrogen atom, preferably as a hydroxyl group —OH, a thiol groups —SH, an amine group —NH— or —NH2, a carboxyl group —COOH, or an amide group —CONH— or —CONH2.

Abstract: A process for preparing &agr;-functionalized thiazolidines or oxazolidines, each of which are oxycarbonyl-functionalized in the 4-position, by adding a base to a reaction mixture comprising an oxycarbonyl-functionalized thiazolidine or oxazolidine and an electrophile at a temperature of greater than −40° C.

Abstract: The invention relates to radioactive stents, characterized in that the stent is coated on the surface with the radioactive isotope, as well as processes for their production.

Abstract: A process for preparing an &agr;-haloketone of the formula (1) where R1 is an optionally heteroatom-containing and optionally substituted hydrocarbon radical, R2 is a hydrogen, alkyl, aralkyl or aryl radical, and X is a halogen radical, by reacting a carboxylic acid derivative of the general formula (2) where L is a leaving group, with a mono- or dienolate of a silyl ester of the formula (3) where R3 and R4 are identical or different alkyl, aryl, alkenyl or aralkyl radicals; and hydrolyzing the reaction product immediately afterwards by adding acid and decarboxylating to (1). The product &agr;-haloketone may be reduced to the corresponding &agr;-haloalcohol.

Abstract: Silanes of the formula

Abstract: A process for preparing an &agr;-haloketone of the formula (1) 1

Abstract: New chelating agents as well as their tricarbonyl complexes with technetium and rhenium and the use of these compounds in radiodiagnosis and radiotherapy are described. The new chelating agents are coupled to substances that accumulate in the diseased tissue.

Abstract: The invention relates to a process for therapeutic treatment of proliferative diseases, which is characterized in that first an administration catheter is placed on the site of the lesion, and a radioactive substance is administered topically via the catheter, then the catheter is again removed, and the radioactive substance remains on the site of the lesion.

Abstract: The invention relates to microparticle preparations made of biodegradable copolymers for use in treatment and diagnosis, especially ultrasonic diagnosis, as well as a process for their production.

Abstract: The invention relates to microparticle preparations made of biodegradable copolymers for use in treatment and diagnosis, especially ultrasonic diagnosis, as well as a process for their production.

Abstract: This invention relates to colloidal systems charged with polymethine dyes and having suitable photophysical and pharmacological properties, their use as a contrast medium in fluorescence and transillumination diagnostics in the near infrared spectral range, as well as methods for their production.

Abstract: The invention relates to a process for therapeutic treatment of proliferative diseases, which is characterized in that first an administration catheter is placed on the site of the lesion, and a radioactive substance is administered topically via the catheter, then the catheter is again removed, and the radioactive substance remains on the site of the lesion.