Abstract: The invention relates to a piston for an internal combustion engine formed from a lower part and an upper part which are threadingly connected to one another to form a piston. In one example, an anti-rotation safeguard device is used to prevent unwanted rotation of the upper part relative to the lower part. In another example, a forged extension and a nut are used to obtain a prestress during operation of the piston. In another example, a cooling gallery including extension bores are used to increase the cooling capacity.

Abstract: A method of analyzing a biological sample using an analyzer and an assay. The method comprises providing the assay for producing the signal. The assay has two or more predetermined number of components. Each of the predetermined components has a distinct relation between the intensive property and the signal. The method further comprises providing calibration samples with known values for the intensive property and measuring a calibration signal for each of the calibration samples. The method further comprises determining a calibration by fitting a calibration function to the calibration signal for each of the calibration samples and the known values for the intensive property. The calibration function is equivalent to a constant plus an exponential decay term for each of the predetermined number of components. The method further comprises measuring the signal of the sample using the analyzer and the assay, and calculating the intensive property using the calibration.

Abstract: The invention relates to a piston for an internal combustion engine formed from a lower part and an upper part which are threadingly connected to one another to form a piston. In one example, an anti-rotation safeguard device is used to prevent unwanted rotation of the upper part relative to the lower part. In another example, a forged extension and a nut are used to obtain a prestress during operation of the piston. In another example, a cooling gallery including extension bores are used to increase the cooling capacity.

Abstract: The invention relates to a method for producing a cooling channel piston, wherein a blank of the cooling channel piston, which has a cavity designed as a cooling channel, is provided and wherein an inlet or outlet opening is introduced into the blank in the direction of the cooling channel, characterized in that the opening is introduced into the blank by means of a CNC-controlled circular milling process by using a special milling cutter having end cutting edges arranged in a shaft profile.

Abstract: The invention relates to a piston for an internal combustion engine formed from a lower part and an upper part which are threadingly connected to one another to form a piston. In one example, an anti-rotation safeguard device is used to prevent unwanted rotation of the upper part relative to the lower part. In another example, a forged extension and a nut are used to obtain a prestress during operation of the piston. In another example, a cooling gallery including extension bores are used to increase the cooling capacity.

Abstract: A method of analyzing a biological sample using an analyzer and an assay. The method comprises providing the assay for producing the signal. The assay has two or more predetermined number of components. Each of the predetermined components has a distinct relation between the intensive property and the signal. The method further comprises providing calibration samples with known values for the intensive property and measuring a calibration signal for each of the calibration samples. The method further comprises determining a calibration by fitting a calibration function to the calibration signal for each of the calibration samples and the known values for the intensive property. The calibration function is equivalent to a constant plus an exponential decay term for each of the predetermined number of components. The method further comprises measuring the signal of the sample using the analyzer and the assay, and calculating the intensive property using the calibration.

Abstract: Provided are a method, system and program for gathering configuration settings from a source system to apply to a target system. A source system is queried to determine configuration settings in the source system. A target system is queried to determine configuration settings in the target system. A user is enabled to enter configuration settings. The determined and user entered configuration settings are processed to generate commands to configure the target system to implement the configuration settings in the source system. The generated commands are executed to configure the target system.

Abstract: Provided are a method, system and program for gathering configuration settings from a source system to apply to a target system. A source system is queried to determine configuration settings in the source system. A target system is queried to determine configuration settings in the target system. A user is enabled to enter configuration settings. The determined and user entered configuration settings are processed to generate commands to configure the target system to implement the configuration settings in the source system. The generated commands are executed to configure the target system.

Abstract: Beta-lactam antibiotics are synthesized by reacting an amino-beta-lactam component with a corresponding amino-group-containing acylating side-chain component in the presence of penicillin amidase from E. coli covalently immobilized on support particles. The resulting beta-lactam antibiotic product is solubilized by adding an acid such as sulfuric acid to lower the pH to 1.0 at a temperature in the range of 0° C. to +5° C. The immobilized penicillin amidase is substantially inactivated by the acid. After separating the beta-lactam antibiotic product, the immobilized penicillin amidase is substantially reactivated for reuse in antibiotic synthesis by treatment with a buffer having about a neutral pH. Antibiotics that can be produced include ampicillin, amoxicillin, cephalexin, cefaclor and cefadroxil.

Abstract: A high surface area system is provided with latex particles for immobilization of substances containing nucleophilic groups. The high surface area system is formed by aggregating the latex particles or by bonding the latex particles to a porous support of high surface area. The latex particles contain groups such as oxirane groups that react with the nucleophilic groups. The substances containing nucleophilic groups may be enzymes or proteins such as albumin, immunoglobulins, blood-clotting factors, cell-membrane proteins or peptide hormones. The high surface area system may be used as a sorbent in removing pollutants, as a stationary phase in organic synthesis such as peptide synthesis, and in the therapeutic treatment of a patient.

Abstract: What is disclosed is a method for preparing carrier systems, adaptable to the covalent bonding thereto of biologically active materials, consisting of a known solid support material having a surface coated with a polymer containing functional groups suitable for covalent bonding, by coating the support material with a film-forming polymer dispersion and a non-film-forming polymer dispersion, suitably in admixture, at least one of the two polymer dispersions containing a polymer having functional groups suitable for covalent bonding with a biologically active material.

Abstract: A copolymer, adaptable to use as a bead-like carrier material for affinity chromatography, of a hydrophilic allyl monomer of the formula CH.sub.2 .dbd.CH--CH.sub.2 --O--R--X.sub.n, wherein n is 0 and R is hydrogen, or n is a whole number from 1 to 5 and R is an (n+1)-valent aliphatic hydrocarbon group, and X is the same or different hydrophilic hydroxylic group, which copolymer is crosslinked by units of a polyfunctional comonomer in which at least two ethylenically unsaturated groups are linked by a chain containing a carbonamide or ether group.

Abstract: Methods for adsorbing a protein, for example an enzyme, onto an insoluble, solid, macroporous, small-particle support by washing said support with an aqueous solution of the protein containing an electrolyte in an ionic strength of at least 0.15 mole/liter and crosslinking said protein, before, during, or after such adsorption, with a coupling component present in aqueous electrolyte-containing solution.

Abstract: Polymer particles dispersible to form a latex and latices of such polymer particles, said particles being adaptable to the fixing or bonding thereto of a biologically active substance and having a core-shell construction wherein the polymer material of the core determines the stability of the form of the latex particles and their redispersibility, and the material of the shell(1) is so hydrophilic that it would be completely or largely water soluble if it were not anchored to the core material and/or crosslinked,(2) contains functional groups which are suitable for the covalent fixation or bonding of biological active substances, and(3) in an anhydrous condition has a T.sub..lambda.max from 20.degree.-250.degree. C., depending on its composition, and methods for bonding a biologically active substance to such particles, for example to prepare a diagnostic reagent.

Abstract: Antigenic substances having amino and/or carboxyl groups are bound covalently, with preservation of their electrochemical state, that is with preservation of the amino and/or carboxyl groups, to a particulate carrier which is not decomposable in the body of a vertebrate; such substances are introduced as an antigen into the body of a vertegrate to provoke an immune response of high specificity and long duration.

Abstract: Polymer particles dispersible to form a latex and latices of such polymer particles, said particles being adaptable to the fixing or bonding thereto of a biologically active substance and having a core-shell construction wherein the polymer material of the core determines the stability of the form of the latex particles and their redispersibility, and the material of the shell(1) is so hydrophilic that it would be completely or largely water soluble if it were not anchored to the core material and/or crosslinked,(2) contains functional groups which are suitable for the covalent fixation or bonding of biological active substances, and(3) in an anhydrous condition has a T.sub..lambda.max from 20.degree.-250.degree. C., depending on its composition, and methods for bonding a biologically active substance to such particles, for example to prepare a diagnostic reagent.

Abstract: The invention relates to diagnostic agents for the rapid diagnostic detection of blood in excretions and body fluids, consisting essentially of a solid support which is charged with a chromogenic substance as indicator and impregnated with an acrylic and/or methacrylic resin.