Abstract: The present invention relates to the use of (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid of formula (I), prefer-ably in form of one of its salts or solvates or hydrates, preferably (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(triflu-oromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid in form of monohydrate (I) of formula (I-M-I) or (5S)-{[2-(4-carboxyphenyl)ethyl] [2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)-ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid inform of mono hydrate (II) of formula (I-M-II), in the inhalative treatment of car-diopulmonary and pulmonary disorders, such as pulmonary arterial hypertension (P AH), chronic tromboembolic pulmonary hyperten-sion (CTEPH) and pulmonary hypertension (PH) associated with chronic lung disease (PH group 3) such as pulmonary hypertension in chronic obstructive pu

Abstract: Examples described herein relate to monitoring a carbon efficiency metric associated with a data center and determining a recommendation to improve the carbon efficiency metric. A data processing device may determine a carbon efficiency metric associated with a data center based on determining a power consumption of an infrastructure device of the data center. The data processing device may determine the carbon efficiency metric further based on estimating a performance of the infrastructure device based on the power consumption. The data processing device may also determine a recommendation to change the data center to improve the carbon efficiency metric based on predicting, using a machine learning model and based on a time-series dataset, whether the carbon efficiency metric is associated with a temporary event. The data processing device may provide the recommendation to an output device.

Abstract: The present invention relates to the use of (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid of formula (I), prefer-ably in form of one of its salts or solvates or hydrates, preferably (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid in form of monohydrate (I) of formula (I-M-I) or (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)-ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid inform of mono hydrate (II) of formula (I-M-II), in the inhalative treatment of cardiopulmonary and pulmonary disorders, such as pulmonary arterial hypertension (P AH), chronic tromboembolic pulmonary hypertension (CTEPH) and pulmonary hypertension (PH) associated with chronic lung disease (PH group 3) such as pulmonary hypertension in chronic obstructive pulmon

Abstract: Predictive big data capacity planning is described. An example includes instructions for receiving workload data and computing operation data related to workload processing for a customer in a computing infrastructure, the computing infrastructure including one or more clusters, the one or more clusters including one or more data nodes; analyzing the received data to identify relationship information between the workload data and the computing operation data; performing predictive analytics to identify a significant value that relates to performance variations in workload performance or usage pattern characteristics for data growth scale factors in the computing infrastructure; generating a knowledge base based at least in part on the predictive analytics; training a machine learning model based at least in part on the knowledge base; and utilizing the trained machine learning model to generate a computing infrastructure configuration recommendation for the customer.

Abstract: A lighting system for illuminating an environment is provided. The lighting system comprises at least one controllable light source for generating a light with at least one controllable light parameter, at least one light sensor for detecting a current lighting level in the environment, and a control unit for controlling the at least one light source, wherein the control unit is configured to evaluate sensor data received from the at least one light sensor to determine a current daylight level and to control the at least one controllable light source using a predefined HCL target curve and based on the determined current daylight level. Furthermore, a method for illuminating an environment is provided.

Abstract: The present invention relates to the use of (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid of formula (I), prefer-ably in form of one of its salts or solvates or hydrates, preferably (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid in form of monohydrate (I) of formula (I-M-I) or (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)-ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid inform of mono hydrate (II) of formula (I-M-II), in the inhalative treatment of cardiopulmonary and pulmonary disorders, such as pulmonary arterial hypertension (P AH), chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary hypertension (PH) associated with chronic lung disease (PH group 3) such as pulmonary hypertension in chronic obstructive pulmo

Abstract: A lighting system has at least one light fixture and a control device. The at least one light fixture has light parameters. The control device is in communication with the at least one light fixture. The control device has a plurality of one-dimensional user setting, a predetermined sequence of light parameters as a function of time, and an adjustment to the predetermined sequence as a function of a selected one-dimensional user setting.

Abstract: Systems and methods are provided for detecting anomalies on multiple layers of a computer system, such as a compute server. For example, the system can detect anomalies from the lower firmware layer up to the upper application layer of the compute server. The system collects train data from the computer system that is under testing. The train data includes features that affect performance metrics, as defined by a selected benchmark. This train data is used in training machine learning (ML) models. The ML models create a train snapshot corresponding to the selected benchmark. Additionally with every new release, a test snapshot can be created corresponding to the selected benchmark or workload. The system can detect an anomaly based on the train snapshot and the test snapshot. Also, the system can recommend tunings for a best set of features based upon data collected over generations of compute server.

Abstract: Systems and methods are provided for detecting anomalies on multiple layers of a computer system, such as a compute server. For example, the system can detect anomalies from the lower firmware layer up to the upper application layer of the compute server. The system collects train data from the computer system that is under testing. The train data includes features that affect performance metrics, as defined by a selected benchmark. This train data is used in training machine learning (ML) models. The ML models create a train snapshot corresponding to the selected benchmark. Additionally with every new release, a test snapshot can be created corresponding to the selected benchmark or workload. The system can detect an anomaly based on the train snapshot and the test snapshot. Also, the system can recommend tunings for a best set of features based upon data collected over generations of compute server.

Abstract: The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

Abstract: The invention relates to substituted dihydropyrazolo pyrazine carboxamide derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and diabetes, and also urogenital and ophthalmic disorders.

Abstract: Predictive big data capacity planning is described. An example includes instructions for receiving workload data and computing operation data related to workload processing for a customer in a computing infrastructure, the computing infrastructure including one or more clusters, the one or more clusters including one or more data nodes; analyzing the received data to identify relationship information between the workload data and the computing operation data; performing predictive analytics to identify a significant value that relates to performance variations in workload performance or usage pattern characteristics for data growth scale factors in the computing infrastructure; generating a knowledge base based at least in part on the predictive analytics; training a machine learning model based at least in part on the knowledge base; and utilizing the trained machine learning model to generate a computing infrastructure configuration recommendation for the customer.

Abstract: A lighting system comprises one or more illuminants and a control device for adjusting light parameters of the illuminants during operation. The control device is arranged to adjust the light parameters time-dependently according to a predetermined course of the light parameters. The control device is further adapted to receive a one-dimensional user setting and to change the course of the light parameters according to the one-dimensional user setting.

Abstract: Examples described herein relate to a management node and a method for managing migration of workload resources. The management node may assign a capability tag to each of a plurality of member nodes hosting workload resources. Further, the management node may determine a resource requirement classification of each workload resource of the workload resources based on analysis of runtime performance data of each workload resource. Furthermore, the management node may determine a temporal usage pattern classification of each workload resource. Moreover, the management node may determine a migration plan for a candidate workload resource of the workload resources based on the capability tag of each of the plurality of member nodes, the resource requirement classification and the temporal usage pattern classification of each workload resource.

Abstract: A lighting system has at least one light fixture and a control device. The at least one light fixture has light parameters. The control device is in communication with the at least one light fixture. The control device has a plurality of one-dimensional user setting, a predetermined sequence of light parameters as a function of time, and an adjustment to the predetermined sequence as a function of a selected one-dimensional user setting.

Abstract: The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular vascular disorders, preferably thrombotic or thromboembolic disorders and/or thrombotic or thromboembolic complications.

Abstract: A wafer-level packaging based module includes an antenna board and a chip board. The antenna board includes at least one antenna layer with introduced antenna element and a shielding layer with introduced shielding element in the area of the at least one antenna element opposite to the antenna layer. The chip board includes a contacting layer, a rewiring layer opposite to the contacting layer and the shielding layer having at least one shielding element arranged on the rewiring layer. A chip layer having at least one chip is arranged between the contacting layer and the rewiring layer. Further, the chip layer includes at least one via connecting the contacting layer to the rewiring layer.

Abstract: Embodiments described herein are directed to methods and apparatus for power distribution. The apparatus can include a power distribution network for a plurality of integrated circuits (IC). According to embodiments, the power distribution network includes a plurality of overlapping power/ground (PG) plane segments and one or more non-overlapping PG (no-PG) plane segments. Each overlapping-PG plane segment is separated from another overlapping-PG plane segment by at least one no-PG plane segment. The no-PG plane segments can include at least one of a multilayered power (P) plane segment with no ground reference of any PG plane and a multilayered ground (G) plane segment with no power reference of any PG plane.

Abstract: A lighting system comprises one or more illuminants and a control device for adjusting light parameters of the illuminants during operation. The control device is arranged to adjust the light parameters time-dependently according to a predetermined course of the light parameters. The control device is further adapted to receive a one-dimensional user setting and to change the course of the light parameters according to the one-dimensional user setting.

Abstract: The invention relates to substituted dihydroquinazolines and to processes for their preparation and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular for use as antiviral agents, in particular against cytomegalo viruses.