Patents by Inventor Dieter Lohmann

Dieter Lohmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5264432
    Abstract: 5-(w-Aminoacyl)-5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepine-11-ones, and their preparation are disclosed for treatment of antiarrhythmia and as an anticholinergic drug.
    Type: Grant
    Filed: November 4, 1992
    Date of Patent: November 23, 1993
    Assignee: Arzneimittelwerk Dresden G.m.b.H
    Inventors: Carla Ruger, Wolfgang Sauer, Dieter Lohmann, Hildegard Poppe, Reni Bartsch, Arkadij M. Lichoserstov, Natalja V. Kaverina, Alexandr P. Skoldinov, Yekaterina K. Grigoryeva, Yekaterina A. Talmachova, Valentin V. Lyskovzev, Alwina W. Stawrowskaya, Gennadi G. Chichkanov
  • Patent number: 5204464
    Abstract: A method for preparing high bulk density crystalline 3-cyano-2-morpholino-5-(pyrid-4-yl)-pyridine which comprises precipitating a high bulk density crystaline 3-cyano-2-morpholino-5-(pyrid-4-yl)-pyridine from a starting material that is(a) a solution in an inorganic or organic acid, and precipitating with a base, or(b) a solution in a chlorinated hydrocarbon, and precipitating with an aliphatic hydrocarbon, or(c) from an aliphatic ester of an aliphatic carboxylic acid and an aliphatic alcohol.The compact, crystalline 3-cyano-2-morpholino-5-(pyrid-4-yl)-pyridine, so obtained, has a bulk density of from about 220 to about 360 g/l and is most suitable for pharmaceutical preparations.
    Type: Grant
    Filed: March 7, 1991
    Date of Patent: April 20, 1993
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Volker Hagen, Gunter Reck, Brigitte Gentsch, Hans-Joachim Heidrich, Hans-Joachim Jansch, Ingrid Wielop, Dieter Lohmann
  • Patent number: 5192760
    Abstract: New 3-carbalkoxyamino-5-(alpha-aminopropionyl)-5H-dibenz[b,f]azepines of formula I and their pharmaceutically acceptable salts were found to be suitable actives for the treatment of cardiac arrhythmia. Previously unknown 3-carbalkoxyamino-5-(alpha-halogenpropionyl)-5H-dibenz[b,f]azepines are obtained from 3-carbalkoxyamino-5H-dibenz[b,f]azepines by reaction with alpha-halogenpropionyl halides. Through their reaction with ammonia, primary amines or secondary amines, the new 3-carbalkoxyamino-5-(alpha-aminopropionyl)-5H-dibenz[b,f]azepines are obtained, which can be optionally converted into their pharmaceutically acceptable acid addition salts.
    Type: Grant
    Filed: June 29, 1990
    Date of Patent: March 9, 1993
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Helmut Wunderlich, Andreas Stark, Dieter Lohmann, Lothar Zenkar, Reni Bartsch, Hildegard Poppe, Aleksandr P. Skoldinov, Natalja V. Kaverina, Anna N. Grizenko, Valentin V. Lyskovzev, Ekaterina K. Grigoreva
  • Patent number: 5185341
    Abstract: The substituted 5-(phenoxyalkanoylamino)-uracil compounds have the following formula I: ##STR1## wherein R.sub.1 and R.sub.2 are each independently hydrogen; a branched or linear alkyl group having 1 to 6 carbon atoms; a branched or straight chain alkenyl or alkynyl group having 1 to 6 carbons atoms; a cycloalkyl group having from 3 to 7 carbon atoms or a cycloalkylmethyl group having a cycloalkyl residue of 3 to 7 carbon atoms; or a phenylalkyl group having an alkyl residue having from 1 to 3 carbon atoms and a phenyl residue, the phenyl residue being unsubstituted or having a halogen, methoxy, methyl or trifluoromethyl substituent; R.sub.3 is a hydrogen, methyl or amino groups; R.sub.4 is halogen, methoxy or methyl groups, and n is 1 or 2.
    Type: Grant
    Filed: November 4, 1991
    Date of Patent: February 9, 1993
    Assignee: Arzneimittelwerk Dresden GMBH
    Inventors: Wolfgang Sauer, Hans-Joachim Jansch, Angelika Rostock, Gottfried Faust, Christine Siegemund, Dieter Lohmann, Reni Bartsch
  • Patent number: 5116974
    Abstract: New 3-carbalkoxyamino-5-aminoacyl-5H-dibenz[b,f]azepines and their pharmaceutically acceptable acid addition salts, and methods for their synthesis are described. These compounds are useful as antiarrhythmic agents in the treatment of heart disorders. The new compounds are made by reacting a 3-carbalkoxyamino-5-halogenacyl-5H-dibenz[b,f]azepines with an amine to form the desired target product, which can be optionally converted into its pharmaceutically acceptable acid addition salt.
    Type: Grant
    Filed: June 29, 1990
    Date of Patent: May 26, 1992
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Helmut Wunderlich, Andreas Stark, Lothar Zenker, Dieter Lohmann, Hildegard Poppe, Reni Bartsch, Aleksandr P. Skoldinov, Natalja V. Kaverina, Anna N. Grizenko, Valentin V. Lyskovzev
  • Patent number: 4997965
    Abstract: Compounds of formula I ##STR1## wherein R.sub.1 is C.sub.1 -C.sub.4 alkyl, phenyl or benzyl,R.sub.2 is C.sub.1 -C.sub.4 alkyl, phenyl or benzyl,a is 0, 1 or 2,R.sub.3 is linear or branched unsubstituted or OH-substituted C.sub.1 -C.sub.12 alkylene or is phenylene,X is --O--, --X-- or --NR.sub.6, wherein R.sub.6 is H, C.sub.1 -C.sub.4 alkyl or --CO--R.sub.5 --OH,b is 0, orb is an integer from 1 to 6 and R.sub.4 is linear or branched unsubstituted or OH-substituted C.sub.1 -C.sub.12 alkylene,Y is --O--, --S-- or --NR.sub.7, wherein R.sub.7 is H or C.sub.1 -C.sub.4 alkyl,R.sub.5 is the divalent radical, diminished by the --CO--O group, of a lactone having a total of 4 to 7 ring members and containing at least one chiral carbon atom and corresponding predominantly to an optically active enantiomeric form, and e is an integer from 1 to 10.These compounds are suitable for the preparation of stationary phases for the chromatographic separation of chiral compounds.
    Type: Grant
    Filed: December 4, 1989
    Date of Patent: March 5, 1991
    Assignee: Ciba-Geigy Corporation
    Inventors: Dieter Lohmann, Richard Dappen
  • Patent number: 4997966
    Abstract: A compound of formula I ##STR1## wherein R.sub.1 is C.sub.1 -C.sub.4 alkyl, phenyl or benzyl,R.sub.2 is C.sub.1 -C.sub.4 alkyl, phenyl or benzyl,a is 0, 1 or 2,R.sub.3 is linear or branched unsubstituted or OH-substituted C.sub.1 -C.sub.12 alkylene or is phenylene,R.sub.5 is the divalent radical, diminished by the --CO--O group, of a lactone having a total of 4 to 7 ring members and containing at least one chiral carbon atom and corresponding predominantly to an optically active enantiomeric form,R.sub.4 is a direct bond, C.sub.1 -C.sub.4 alkyl--CH or CF.sub.3 --CH, andY is phenyl, naphthyl, fluorenyl or anthryl, each unsubstituted or substituted by C.sub.1 -C.sub.12 alkyl, C.sub.1 -C.sub.12 alkoxy, halogen, --CN or --NO.sub.2.These compounds are suitable for the preparation of stationary phases for the chromatographic separation of chiral compounds.
    Type: Grant
    Filed: December 7, 1989
    Date of Patent: March 5, 1991
    Assignee: Ciba-Geigy Corporation
    Inventors: Dieter Lohmann, Richard Dappen
  • Patent number: 4605712
    Abstract: Polysiloxanes of uniform molecular weight (MW) distribution with 500-10,000 MW segments of polysiloxane and containing at least one vinyl group connected to said polysiloxane segments through intervening alkylene-urea or -urethane linkages are prepared from polysiloxane-polyols, -polyamines or -polythiols by reaction with an unsaturated compound containing an isocyanato moiety, for example 2-isocyanatoethyl methacrylate. The polysiloxanes containing the vinyl groups are useful as radiation- or thermally curable coatings for glass, textiles, plastics, wood, ceramics, metals, as films or bandages for medicinal purposes, or molded shapes, in form of contact lenses, catheters or implants, either by themselves or in combination with other vinyl monomers; and are particularly useful in preparing hard or soft contact lenses, including hydrogel contact lenses.
    Type: Grant
    Filed: September 24, 1984
    Date of Patent: August 12, 1986
    Assignee: Ciba-Geigy Corporation
    Inventors: Karl F. Mueller, Dieter Lohmann, Robert A. Falk
  • Patent number: 4565873
    Abstract: The compounds according to the invention have the formula XIX ##STR1## in which R.sup.1 and R.sup.2 are independently methyl, ethyl, phenyl, vinyl, chlorine or alkoxy, R.sup.3 is chlorine or alkoxy, A.sup.1 is alkylene and Y is substituted ethenylene. These products are to be used as adhesion promoters, especially between inorganic solids and organic resins. 4 processes of preparation are given.
    Type: Grant
    Filed: February 24, 1984
    Date of Patent: January 21, 1986
    Assignee: Ciba-Geigy Corporation
    Inventors: Dieter Lohmann, Siegfried Wyler
  • Patent number: 4425361
    Abstract: Formamido-carbamates of the formula ##STR1## wherein R.sub.1 is ##STR2## R.sub.2 is ##STR3## or R.sub.4 --CH.sub.2 --CH.sub.2 --, R.sub.3 is hydrogen, ##STR4## R.sub.4 is ##STR5## R.sub.5, R.sub.6 and R.sub.7 independently of one another are each hydrogen, halogen or C.sub.1 -C.sub.4 -alkyl,processes for producing them and their use for combating pests are described.
    Type: Grant
    Filed: November 18, 1981
    Date of Patent: January 10, 1984
    Assignee: Ciba-Geigy Corporation
    Inventors: Dieter Lohmann, Christian d'Hondt, Guenter Rist
  • Patent number: 4424359
    Abstract: Vinyl-substituted 2,2'-bipyridine compounds of the formula ##STR1## and complexes thereof with metals or metal compounds other than alkali metals or alkaline earth metals, or alkali metal compounds, or alkaline earth metal compounds are described, R.sub.1 and R.sub.2 being as defined in patent claim 1 and the vinyl group being bonded in the 4-position or 6-position. The 2,2'-bipyridine compounds (I) are suitable for the preparation of complex-forming or complexed, crosslinked or uncrosslinked polymers. Complexed polymers, obtainable from these, are used, for example, as catalysts, in particular for transvinylation reactions. Uncomplexed polymers, which can be prepared from compounds (I), are suitable as metal ion scavengers in various applications.
    Type: Grant
    Filed: July 27, 1981
    Date of Patent: January 3, 1984
    Assignee: Ciba-Geigy Corporation
    Inventors: Ju/ rgen Kaschig, Dieter Lohmann
  • Patent number: 4417057
    Abstract: Compounds of the formulae I or II ##STR1## and processes for their preparation are described. In the above formulae, Z is a tetravalent aliphatic radical, which can be interrupted by hetero-atoms, or a substituted or unsubstituted tetravalent cycloaliphatic radical, which can contain hetero-atoms and/or can be fused to a benzene ring, A is --C(R.sup.4).dbd.C(R.sup.5)(R.sup.6) or --C.tbd.C--R.sup.5, especially --CH.dbd.CH.sub.2, R.sup.1 and R.sup.2 independenty of one another are H, methyl, phenyl, --CN or Cl, or together are trimethylene, tetramethylene, ##STR2## R.sup.3 is a direct bond, C.sub.1-8 alkylene, cyclohexylene, phenylene or --CH.sub.2 -phenylene with the --CH.sub.2 group bonded to the N atom, R.sup.4 and R.sup.6 independently of one another are H, methyl or ethyl and R.sup.5 is H or C.sub.1-9 alkyl. The compunds of the formula I and II are valuable intermediates for the preparation of silicon-modified adhesion promoters.
    Type: Grant
    Filed: June 26, 1981
    Date of Patent: November 22, 1983
    Assignee: Ciba-Geigy Corporation
    Inventors: Dieter Lohmann, Martin Roth, Marcus Baumann
  • Patent number: 4364808
    Abstract: The compounds according to the invention have the formula I ##STR1## in which R.sup.1, R.sup.2 and R.sup.3 are monovalent organic radicals or chlorine and Z is a tetravalent organic radical and A is a divalent organic grouping. These products are to be used as adhesion promoters, especially between inorganic solids and organic resins. 4 processes of preparation are given.
    Type: Grant
    Filed: December 15, 1980
    Date of Patent: December 21, 1982
    Assignee: Ciba-Geigy Corporation
    Inventors: Dieter Lohmann, Siegfried Wyler
  • Patent number: 4359555
    Abstract: Salts of formamidines with polymers containing sulfonic acid groups; processes for producing these salts; and the use thereof in combating pests.
    Type: Grant
    Filed: June 18, 1980
    Date of Patent: November 16, 1982
    Assignee: Ciba-Geigy Corporation
    Inventors: Christian d'Hondt, Dieter Lohmann, Ernst Neuenschwander
  • Patent number: 4336353
    Abstract: Salts of 3-methyl-2-(2',4'-dimethyl-phenylimino)-4-thiazoline with polymers containing sulfonic acid groups, processes for producing them, and their use in combating pests.
    Type: Grant
    Filed: September 2, 1980
    Date of Patent: June 22, 1982
    Assignee: Ciba-Geigy Corporation
    Inventors: Christian d'Hondt, Dieter Lohmann, Ernst Neuenschwander
  • Patent number: 4301075
    Abstract: Compounds of the formulae I or II ##STR1## and processes for their preparation are described. In the above formulae, Z is a tetravalent aliphatic radical, which can be interrupted by hetero-atoms, or a substituted or unsubstituted tetravalent cycloaliphatic radical, which can contain hetero-atoms and/or can be fused to a benzene ring, A is --C(R.sup.4).dbd.C(R.sup.5)(R.sup.6) or --C.tbd.C--R.sup.5, especially --CH.dbd.CH.sub.2, R.sup.1 and R.sup.2 independently of one another are H, methyl, phenyl, --CN or Cl, or together are trimethylene, tetramethylene, ##STR2## R.sup.3 is a direct bond, C.sub.1-8 alkylene, cyclohexylene, phenylene or --CH.sub.2 -phenylene with the --CH.sub.2 group bonded to the N atom, R.sup.4 and R.sup.6 independently of one another are H, methyl or ethyl and R.sup.5 is H or C.sub.1-9 alkyl. The compounds of the formula I and II are valuable intermediates for the preparation of silicon-modified adhesion promoters.
    Type: Grant
    Filed: August 20, 1979
    Date of Patent: November 17, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Dieter Lohmann, Martin Roth, Marcus Baumann
  • Patent number: 4271074
    Abstract: The compounds according to the invention have the formula I ##STR1## in which R.sup.1, R.sup.2 and R.sup.3 are monovalent organic radicals or chlorine and Z is a tetravalent organic radical and A is a divalent organic grouping. These products are to be used as adhesion promoters, especially between inorganic solids and organic resins. 4 processes of preparation are given.
    Type: Grant
    Filed: August 20, 1979
    Date of Patent: June 2, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Dieter Lohmann, Siegfried Wyler
  • Patent number: 4196233
    Abstract: A process for coating inorganic substrates, especially metallic or metalloid substrates, sintered metal carbides and carbon materials with carbides, nitrides and/or carbonitrides, using certain nitriles as sources of carbon and nitrogen, is described. High deposition rates and smooth coatings of good to very good adhesion are achievable by this process.
    Type: Grant
    Filed: July 6, 1977
    Date of Patent: April 1, 1980
    Assignee: Ciba-Geigy Corporation
    Inventors: Diethelm Bitzer, Dieter Lohmann
  • Patent number: 4124651
    Abstract: A process for producing polyamide-polyamide-acid copolymers having an inherent viscosity of from 0.1 to 2.5 and cyclized derivatives thereof is disclosed, which process comprises reacting a polyamide-acid block having an average molecular weight of from 750 to 20,000 with a dicarboxylic acid dichloride and a diamine. The resultant polyamide-polyamide-acid copolymers are distinguished by good processing characteristics as well as good electrical, thermal and/or mechanical properties.
    Type: Grant
    Filed: August 17, 1977
    Date of Patent: November 7, 1978
    Assignee: Ciba-Geigy Corporation
    Inventors: Dieter Lohmann, Peter Furrer, Roland Darms, Gerd Greber
  • Patent number: 4053496
    Abstract: The present invention relates to partially polymerized products obtained by hydrolysis of .beta.-halogenoethyl-silanes and to the hydrolysis of the said monomeric silanes with water or an aqueous medium. The dimers are the preferred final products. The invention is further concerned with agents and methods for the regulation and control of plant development, especially for promoting fruit abcission as well as resin and latex flow in trees, using the said partially polymerized .beta.-halogeno silane hydrolysates as the active ingredients.
    Type: Grant
    Filed: January 8, 1976
    Date of Patent: October 11, 1977
    Assignee: Ciba-Geigy Corporation
    Inventors: Werner Fory, Hanspeter Fischer, Dieter Lohmann, Gerd Greber