Patents by Inventor Dieter Ruchatz

Dieter Ruchatz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TABLET CONTAINING VALSARTAN AND SACUBITRIL
    Publication number: 20230346709
    Abstract: The present invention relates to a tablet for oral administration containing valsartan and sacubitril, preferably as sodium salts or as a complex of valsartan disodium and sacubitril monosodium, preferably LCZ696. The tablet is prepared by dry-granulation or direct compression and contains a mesoporous inorganic stabilizer, e.g. mesoporous silica (Syloid®).
    Type: Application
    Filed: April 25, 2023
    Publication date: November 2, 2023
    Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Bala Ramesha Chary RALLABANDI, Vamshi Ramana PRATHAP, Krishna Mohan GOLLAPUDI, Bala Subramanian VELUSAMY, Srimannarayana BANDLA, Hendrik SCHLEHAHN, Dieter RUCHATZ
  • STABLE HOT-MELT EXTRUDATE CONTAINING VALSARTAN AND SACUBITRIL
    Publication number: 20220226247
    Abstract: The present invention relates to a solid unit dosage form for oral administration (tablet or granules) containing a solid dispersion of valsartan and sacubitril in a polymeric matrix. The solid dispersion is prepared by hot-melt extrusion and may contain the active ingredients preferably in a non-crystalline state. LCZ696, (pseudo)polymorphic forms thereof as well as the individual drugs, e.g. valsartan disodium and sacubitril monosodium, may be subjected to the hot-melt extrusion process.
    Type: Application
    Filed: April 7, 2022
    Publication date: July 21, 2022
    Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Bala Ramesha Chary RALLABANDI, Vamshi Ramana PRATHAP, Rajesh Krishna Mohan GOLLAPUDI, Hendrik SCHLEHAHN, Dieter RUCHATZ
  • STABLE HOT-MELT EXTRUDATE CONTAINING VALSARTAN AND SACUBITRIL
    Publication number: 20210085610
    Abstract: The present invention relates to a solid unit dosage form for oral administration (tablet or granules) containing a solid dispersion of valsartan and sacubitril in a polymeric matrix. The solid dispersion is prepared by hot-melt extrusion and may contain the active ingredients preferably in a non-crystalline state. LCZ696, (pseudo)polymorphic forms thereof as well as the individual drugs, e.g. valsartan disodium and sacubitril monosodium, may be subjected to the hot-melt extrusion process.
    Type: Application
    Filed: March 29, 2018
    Publication date: March 25, 2021
    Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Bala Ramesha Chary RALLABANDI, Vamshi Ramana PRATHAP, Rajesh Krishna Mohan GOLLAPUDI, Hendrik SCHLEHAHN, Dieter RUCHATZ
  • TABLET CONTAINING VALSARTAN AND SACUBITRIL
    Publication number: 20200276129
    Abstract: The present invention relates to a tablet for oral administration containing valsartan and sacubitril, preferably as sodium salts or as a complex of valsartan disodium and sacubitril monosodium, preferably LCZ696. The tablet is prepared by dry-granulation or direct compression and contains a mesoporous inorganic stabilizer, e.g. mesoporous silica (Syloid®).
    Type: Application
    Filed: October 12, 2018
    Publication date: September 3, 2020
    Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Bala Ramesha Chary RALLABANDI, Vamshi Ramana PRATHAP, Krishna Mohan GOLLAPUDI, Bala Subramanian VELUSAMY, Srimannarayana BANDLA, Hendrik SCHLEHAHN, Dieter RUCHATZ
  • Cycloolefin copolymers, a process for their preparation and the use thereof and catalysts
    Patent number: 8236910
    Abstract: Cycloolefin copolymers which are distinguished by the presence of racemic diads of repeating polycyclic units and additionally by racemic triads of repeating polycyclic units are described. These copolymers can be prepared by copolymerization of polycyclic olefins with linear olefins in the presence of metallocene catalysts which have no Cs symmetry in relation to the centroid-M-centroid plane. The novel copolymers can be used for the production of shaped articles, in particular of films.
    Type: Grant
    Filed: March 19, 2008
    Date of Patent: August 7, 2012
    Assignee: Topas Advanced Polymers GmbH
    Inventors: Dieter Ruchatz, Anne-Meike Schauwienold, Peter Jörg
  • Cycloolefin copolymers, a process for their preparation and the use thereof and catalysts
    Patent number: 8138286
    Abstract: Cycloolefin copolymers which are distinguished by the presence of racemic diads of repeating polycyclic units and additionally by racemic triads of repeating polycyclic units are described. These copolymers can be prepared by copolymerization of polycyclic olefins with linear olefins in the presence of metallocene catalysts which have no Cs symmetry in relation to the centroid-M-centroid plane. The novel copolymers can be used for the production of shaped articles, in particular of films.
    Type: Grant
    Filed: March 19, 2008
    Date of Patent: March 20, 2012
    Assignee: Topas Advanced Polymers GmbH
    Inventors: Dieter Ruchatz, Anne-Meike Schauwienold, Peter Jörg
  • Cycloolefin copolymers, a process for their preparation and the use thereof and catalysts
    Publication number: 20080242812
    Abstract: Cycloolefin copolymers which are distinguished by the presence of racemic diads of repeating polycyclic units and additionally by racemic triads of repeating polycyclic units are described. These copolymers can be prepared by copolymerization of polycyclic olefins with linear olefins in the presence of metallocene catalysts which have no Cs symmetry in relation to the centroid-M-centroid plane. The novel copolymers can be used for the production of shaped articles, in particular of films.
    Type: Application
    Filed: March 19, 2008
    Publication date: October 2, 2008
    Inventors: Dieter Ruchatz, Anne-Meike Schauwienold, Peter Jorg
  • Method of producing amorphous polyolefins with a wide mole weight distribution
    Patent number: 7026401
    Abstract: The present invention relates to a process for producing a bimodal or multimodal mixture of amorphous polyolefins having a different molar mass, in which at least one amorphous polyolefin having a high molar mass is brought into contact and mixed with at least one amorphous polyolefin having a low molar mass in solution and the solvent is subsequently removed.
    Type: Grant
    Filed: June 21, 2000
    Date of Patent: April 11, 2006
    Assignee: Ticona GmbH
    Inventors: Frank Osan, Klaus Berger, Dieter Ruchatz, Oliver Stark, Toru Nakamura
  • Method for producing a cycloolefin copolymer
    Patent number: 6365686
    Abstract: The invention relates to a method for producing a cycloolefin copolymer by polymerization of 0.1-99.9 wt. %, with respect to the total amount of monomers, of at least one polycyclic olefin, 0-99.9 wt. %, with respect to the total amount of monomers, of at least one monocyclic olefin, 0.1-99.9 wt. %, with respect to the total amount of monomers, of at least one acyclic 1-olefin, in the presence of a catalyst system consisting of at least one cocatalyst and at least one metal coordination complex with taut geometry.
    Type: Grant
    Filed: July 29, 1999
    Date of Patent: April 2, 2002
    Assignee: Ticona GmbH
    Inventors: Alexandra Jacobs, Gerhard Fink, Dieter Ruchatz
  • Method for producing cycloolefin polymers
    Patent number: 6316560
    Abstract: The invention relates to a method for producing a cycloolefin copolymer by polymerization of 0.1-99.0 wt %, with respect to the total amount of monomers, of at least one polycyclic, 0-99.9 wt. %, with respect to the total amount of monomers, of at least one moncyclic olefin, and 0.1-99.9 wt. %, with respect to the total amount of monomers, of at least one acyclic 1-olefin, in the presence of a catalyst system consisting of at least one cocatalyst and at least one metallocene.
    Type: Grant
    Filed: July 29, 1999
    Date of Patent: November 13, 2001
    Assignee: Ticona GmbH
    Inventors: Alexandra Jacobs, Gerhard Fink, Dieter Ruchatz