Patents by Inventor Dieter Sauerbier

Dieter Sauerbier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligopeptide lyophilisate, their preparation and use
    Patent number: 7605121
    Abstract: A novel lyophilizate and method of preparation as well as the use of the lyophilizate to treat female infertility and for gonad protection. Cetrorelix is dissolved in acetic acid 30% v/v, the solution is transferred to water and freeze dried.
    Type: Grant
    Filed: January 24, 2005
    Date of Patent: October 20, 2009
    Assignee: AEterna Zentaris GmbH
    Inventors: Jürgen Engel, Burkhard Wichert, Dieter Sauerbier, Gudrun Sauerbier, legal representative, Thomas Reissmann
  • Oligopeptide lyophilisate, their preparation and use
    Publication number: 20050124546
    Abstract: A novel lyophilizate and method of preparation as well as the use of the lyophilizate to treat female infertility and for gonad protection. Cetrorelix is dissolved in acetic acid 30% v/v, the solution is transferred to water and freeze dried.
    Type: Application
    Filed: January 24, 2005
    Publication date: June 9, 2005
    Inventors: Jurgen Engel, Burkhard Wichert, Dieter Sauerbier, Thomas Reissmann
  • Preparation and use of oligopeptide lyophilisate for gonad protection
    Patent number: 6867191
    Abstract: A lyophilizate, method of preparation, and use of the lyophilizate for gonad protection is described. The lyophilizate comprises cetrorelix dissolved in 30% (v/v) acetic acid, transferred to water, and freeze-dried.
    Type: Grant
    Filed: May 24, 2002
    Date of Patent: March 15, 2005
    Assignee: Zentaris GmbH
    Inventors: Jürgen Engel, Burkhard Wichert, Dieter Sauerbier, Thomas Reissmann
  • Oligopeptide lyophilisate, their preparation and use
    Patent number: 6863891
    Abstract: A novel lyophilizate and method of preparation as well as the use of the lyophilizate to treat female infertility and for gonad protection. Cetrorelix is dissolved in acetic acid 30% v/v, the solution is transferred to water and freeze dried.
    Type: Grant
    Filed: January 9, 2002
    Date of Patent: March 8, 2005
    Assignee: Zentaris AG
    Inventors: Jürgen Engel, Burkhard Wichert, Dieter Sauerbier, Thomas Reissmann
  • Oligopeptide lyophilisate, their preparation and use
    Patent number: 6828415
    Abstract: A novel lyophilizate and method of preparation as well as the use of the lyophilizate to treat female infertility and for gonad protection. Cetrorelix is dissolved in acetic acid 30% v/v, the solution is transferred to water and freeze dried.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 7, 2004
    Assignee: Zentaris GmbH
    Inventors: Jürgen Engel, Burkhard Wichert, Dieter Sauerbier, Thomas Reissmann
  • Solid pharmaceutical compositions containing hexedecylphosphocholine (miltefosine) for oral administration in the treatment of leishmaniasis
    Patent number: 6544551
    Abstract: The present invention relates to new solid pharmaceutical compositions containing hexadecylphosphocholine (miltefosine) for oral administration in the treatment of leishmaniasis, a process for the manufacture of said pharmaceutical composition, a dosage scheme for oral administration of said pharmaceutical composition in the treatment of leishmaniasis, and finally a combination comprising said solid pharmaceutical composition, antiemeticum, and/or an antidiarrhoeal.
    Type: Grant
    Filed: July 24, 2000
    Date of Patent: April 8, 2003
    Assignee: Zentaris AG
    Inventors: Juergen Engel, Werner Sarlikiotis, Thomas Klenner, Peter Hilgard, Dieter Sauerbier, Eckhard Milsmann
  • Oligopeptide lyophilisate, their preparation and use
    Publication number: 20020198186
    Abstract: A novel lyophilizate and method of preparation as well as the use of the lyophilizate to treat female infertility and for gonad protection. Cetrorelix is dissolved in acetic acid 30% V/V, the solution is transferred to water and freeze dried.
    Type: Application
    Filed: May 24, 2002
    Publication date: December 26, 2002
    Applicant: Zentaris AG
    Inventors: Jurgen Engel, Burkhard Wichert, Dieter Sauerbier, Thomas Reissmann
  • Oligopeptide lyophilisate, their preparation and use
    Publication number: 20020103113
    Abstract: A novel lyophilizate and method of preparation as well as the use of the lyophilizate to treat female infertility and for gonad protection. Cetrorelix is dissolved in acetic acid 30% v/v, the solution is transferred to water and freeze dried.
    Type: Application
    Filed: January 9, 2002
    Publication date: August 1, 2002
    Inventors: Jurgen Engel, Burkhard Wichert, Dieter Sauerbier, Thomas Reissmann
  • OLIGOPEPTIDE LYOPHILISATE, THEIR PREPARATION AND USE
    Publication number: 20020099018
    Abstract: A novel lyophilizate and method of preparation as well as the use of the lyophilizate to treat female infertility and for gonad protection. Cetrorelix is dissolved in acetic acid 30% v/v, the solution is transferred to water and freeze dried.
    Type: Application
    Filed: June 6, 1995
    Publication date: July 25, 2002
    Inventors: JURGEN ENGEL, BURKHARD WICHERT, DIETER SAUERBIER, THOMAS REISSMANN
  • CYCLOPHOSPHAMIDE FILM-COATED TABLETS
    Publication number: 20010046504
    Abstract: 1. [sic] The invention relates to film-coated tablets with cyclophosphamide as active compound, which in the core comprise cyclophosphamide, one or more fillers, one or more dry binders but no preswollen starch, flow regulators and lubricants.
    Type: Application
    Filed: June 15, 1999
    Publication date: November 29, 2001
    Inventors: JURGEN ENGEL, JURGEN RAWERT, DIETER SAUERBIER, BURKHARD WICHERT
  • Container for injectable mesna solutions
    Patent number: 5834520
    Abstract: Injectable mesna solutions having a pH value higher than 7.5. The solutions have increased storage stability.
    Type: Grant
    Filed: August 21, 1997
    Date of Patent: November 10, 1998
    Assignee: ASTA-Medica Aktiengesellschaft
    Inventors: Jurgen Engel, Elisabeth Wolf-Heuss, Wolfgang Deger, Giancarlo Camuglia, Dieter Sauerbier
  • Ifosfamide lyophilizate preparations
    Patent number: 5750131
    Abstract: The invention relates to improved ifosfamide preparations which are distinguished in that as primary auxiliary a polysaccharide, in general a glycan, preferably dextran, starches or cellulose, in particular dextrans having an MW of 20,000 to 85,000, modified starches such as hydroxyethyl starch and chemically modified celluloses such as hydroxyethylcellulose and sodium carboxymethylcellulose, a glycol ether, preferably polyethylene glycol, in particular polyethylene glycols having a molecular weight of 600 to 6000 or an amino acid, preferably alanine, leucine or glutamic acid, is added to them.The improved ifosfamide preparation can also contain as an auxiliary a pharmaceutically customary buffer, for example acetate, citrate or tris buffer, preferably phosphate buffer.In addition, improved ifosfamide preparations are obtained by addition of NaHCO.sub.3.The ifosfamide preparations according to the invention can comprise one or a combination of several auxiliaries.
    Type: Grant
    Filed: November 19, 1996
    Date of Patent: May 12, 1998
    Assignee: Asta Medica Aktiengesellschaft
    Inventors: Burkhard Wichert, Dieter Sauerbier, Jurgen Rawert
  • Injectable mesna solutions
    Patent number: 5728738
    Abstract: Injectable mesna solutions having a pH value higher than 7.5. The solutions have increased storage stability.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 17, 1998
    Assignee: ASTA Medica Aktiengesellschaft
    Inventors: Jurgen Engel, Elisabeth Wolf-Heuss, Wolfgang Deger, Giancarlo Camuglia, Dieter Sauerbier
  • Injectable mesna solutions
    Patent number: 5696172
    Abstract: Injectable mesna solutions having a pH value higher than 7.5. The solutions have increased storage stability.
    Type: Grant
    Filed: April 23, 1996
    Date of Patent: December 9, 1997
    Assignee: ASTA Medica Aktiengesellschaft
    Inventors: Jurgen Engel, Elisabeth Wolf-Heuss, Wolfgang Deger, Giancarlo Camuglia, Dieter Sauerbier
  • Stabilized hexadecylphosphocholine solutions in glycerol alkyl ethers
    Patent number: 5446033
    Abstract: Solutions of alkylphosphocholines in glycerol alkyl ethers having enhanced storage stability containing a buffer which maintains the pH value to a range between 4 and 6.
    Type: Grant
    Filed: October 19, 1993
    Date of Patent: August 29, 1995
    Assignee: Asta Medica AG
    Inventors: Jurgen Engel, Elisabeth Wolf-Heuss, Helmut Orth, Burkhard Wichert, Dieter Sauerbier
  • Tablet containing mesna as active substance and method of making same
    Patent number: 5358718
    Abstract: A granulate containing mesna is made by granulating mesna in the presence of an alcohol, acetone or a mixture of one of these with water. The granulate may be converted to tablets, along with other agents. The tablets contain:0.01-1 parts by weight of a binding agent0.03-0.4 parts by weight of a disintegrant0.01-0.2 parts by weight of a lubricant and0.1-1 parts by weight of a filling agent as well as, in the case of an effervescent tablet, an additional 0.05-30 parts by weight of a conventional physiologically acceptable effervescent mixture.
    Type: Grant
    Filed: July 26, 1993
    Date of Patent: October 25, 1994
    Assignee: Degussa
    Inventors: Dieter Sauerbier, Jurgen Engel, Eckhard Milsmann
  • Tablets and granulates containing mesna as active substance
    Patent number: 5262169
    Abstract: A granulate containing mesna is made by granulating mesna in the presence of an alcohol, acetone or a mixture of one of these with water. The granulate may be converted to tablets, along with other agents. The tablets contain:0.01-1 parts by weight of a binding agent0.03-0.4 parts by weight of a disintegrant0.01-0.2 parts by weight of a lubricant and0.1-1 parts by weight of a filling agent as well as, in the case of an effervescent tablet, an additional 0.05-30 parts by weight of a conventional physiologically acceptable effervescent mixture.
    Type: Grant
    Filed: July 16, 1991
    Date of Patent: November 16, 1993
    Assignee: Asta Medica Aktiengesellschaft
    Inventors: Dieter Sauerbier, Jurgen Engel, Eckhard Milsmann
  • Tablets and granulates containing mesna as active substance
    Patent number: 5252341
    Abstract: A granulate containing mesna is made by granulating mesna in the presence of an alcohol, acetone or a mixture of one of these with water. The granulate may be converted to tablets, along with other agents. The tablets contain0.01-1 parts by weight of a binding agent0.03-0.4 parts by weight of a disintegrant0.01-0.2 parts by weight of a lubricant and0.1-1 parts by weight of a filling agent as well as, in the case of an effervescent tablet, an additional 0.05-30 parts by weight of a conventional physiologically acceptable effervescent mixture.
    Type: Grant
    Filed: August 17, 1992
    Date of Patent: October 12, 1993
    Assignee: Degussa Aktiengesellschaft
    Inventors: Dieter Sauerbier, Jurgen Engel, Eckhard Milsmann
  • Azelastine embonate and compositions which contain it
    Patent number: 5232919
    Abstract: An embonic acid salt of azelastine is disclosed which does not possess the bitter taste of azelastine, and which therefore is suitable for orally administered formulations.
    Type: Grant
    Filed: October 15, 1990
    Date of Patent: August 3, 1993
    Assignee: Asta Pharma Aktiengesellschaft
    Inventors: Gerhard Scheffler, Dieter Sauerbier, Jurgen Engel
  • Ifosfamide lyophilisate and process for its preparation
    Patent number: 5204335
    Abstract: Ifosfamide lyophilizate consisting substantially of ifosfamide and 0.1 to 17 parts by weight of a hexitol.
    Type: Grant
    Filed: May 21, 1991
    Date of Patent: April 20, 1993
    Assignee: Asta Pharma Aktiengesellschaft
    Inventors: Dieter Sauerbier, Uwe-Peter Dammann, Otto Isaac