Patents by Inventor Diether Recktenwald

Diether Recktenwald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9535065
    Abstract: The present disclosure provides cytometric methods for the detection of rare target cells in a sample. In certain aspects, the methods and compositions may facilitate the detection of rare target cells, such as circulating tumor cells (CTCs), in a biological sample such as blood. Aspects of the methods include contacting the sample with first and second binding members that specifically bind to a marker of the rare target cell, and cytometrically assaying the sample for the presence of cells comprising bound first and second binding members to detect the rare target cell in the sample. Also provided are systems, compositions, and kits for practicing the subject methods.
    Type: Grant
    Filed: September 6, 2012
    Date of Patent: January 3, 2017
    Assignee: Becton, Dickinson and Company
    Inventors: Hrair Kirakossian, Edward Goldberg, Diether Recktenwald
  • Publication number: 20140242610
    Abstract: The present disclosure provides cytometric methods for the detection of rare target cells in a sample. In certain aspects, the methods and compositions may facilitate the detection of rare target cells, such as circulating tumor cells (CTCs), in a biological sample such as blood. Aspects of the methods include contacting the sample with first and second binding members that specifically bind to a marker of the rare target cell, and cytometrically assaying the sample for the presence of cells comprising bound first and second binding members to detect the rare target cell in the sample. Also provided are systems, compositions, and kits for practicing the subject methods.
    Type: Application
    Filed: September 6, 2012
    Publication date: August 28, 2014
    Applicant: BECTON, DICKINSON AND COMPANY
    Inventors: Hrair Kirakossian, Edward Goldberg, Diether Recktenwald
  • Publication number: 20060240411
    Abstract: Arrays of microparticle populations, each population labeled with a single fluorescent dye, are provided for use in multiplex assays. The populations form a virtual multidimensional array wherein each microparticle is identified by fluorescence intensity in two different fluorescence detection channels. The arrays are useful in a variety of assays, including multiplex, multi-analyte assays for the simultaneous detection of two or more analytes by, for example, flow cytometry, and a labeling reagents in, for example, microscopy. The use of singly-dyed microparticles to form multidimensional arrays greatly simplifies the creation of multiplex assays.
    Type: Application
    Filed: April 14, 2006
    Publication date: October 26, 2006
    Applicant: Becton, Dickinson and Company
    Inventors: Majid Mehrpouyan, Diether Recktenwald, Rudolf Varro