Abstract: The invention relates to composite materials (organosheets) containing a thermoplastic molding compound, at least one continuous reinforcing fiber layer and at least one inorganic filler material. According to the invention, a sheet material consisting of continuous reinforcing fibers in a matrix composition comprising the molding compound is used, the thermoplastic molding compound containing at least one polyolefin, and optionally at least one further, polarity-functionalized polymer. The invention also relates to a process for produci2023ng the claimed composite material and to uses thereof.

Abstract: Provided herein multispecific (e.g., bispecific) binding molecules comprising a first binding domain that binds an extracellular portion of dystroglycan and a second binding domain that binds laminin-2. Further provided herein are methods for making such binding molecules and uses of such binding molecules for treating and/or preventing alpha-dystroglycanopathies.

Abstract: Provided herein multispecific (e.g., bispecific) binding molecules comprising a first binding domain that binds an extracellular portion of dystroglycan and a second binding domain that binds laminin-2. Further provided herein are methods for making such binding molecules and uses of such binding molecules for treating and/or preventing alpha-dystroglycanopathies.

Abstract: Provided herein multispecific (e.g., bispecific) binding molecules comprising a first binding domain that binds an extracellular portion of dystroglycan and a second binding domain that binds laminin-2. Further provided herein are methods for making such binding molecules and uses of such binding molecules for treating and/or preventing alpha-dystroglycanopathies.

Abstract: Provided herein multispecific (e.g., bispecific) binding molecules comprising a first binding domain that binds an extracellular portion of dystroglycan and a second binding domain that binds laminin-2. Further provided herein are methods for making such binding molecules and uses of such binding molecules for treating and/or preventing alpha-dystroglycanopathies.

Abstract: An elastomer bearing, includes a cylindrical inner metal part, a metallic outer sleeve arranged at a radial distance around the inner metal part; and an elastomer part arranged between the inner metal part and the metallic outer sleeve. The elastomer part has an outer sheath provided with a plastic layer. The outer sleeve is constructed as a one-piece extruded part made of lightweight metal, and the outer sleeve has an inner sheath surface provided with a profiling which form fittingly engages in the plastic layer.

Abstract: A light metal cylinder crankcase for combustion engines has cylinder bushings with a running layer that forms the running surface and a rough, external bonding layer for bonding the cylinder bushings to the cylinder crankcase while pouring the cylinder crankcase. At least 60% of the bonding layer relative to the jacket surface of the bonding layer is connected with the casting material of the cylinder crankcase in a material tight manner.

Abstract: A light metal cylinder crankcase for combustion engines has cylinder bushings with a running layer that forms the running surface and a rough, external bonding layer for bonding the cylinder bushings to the cylinder crankcase while pouring the cylinder crankcase. At least 60% of the bonding layer relative to the jacket surface of the bonding layer is connected with the casting material of the cylinder crankcase in a material tight manner.

Abstract: A light metal cylinder crankcase for combustion engines has cylinder bushings with a running layer that forms the running surface and a rough, external bonding layer for bonding the cylinder bushings to the cylinder crankcase while pouring the cylinder crankcase. At least 60% of the bonding layer relative to the jacket surface of the bonding layer is connected with the casting material of the cylinder crankcase in a material tight manner.