Patents by Inventor Dietmar Seemann
Dietmar Seemann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9139557Abstract: The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. The carboxamide compounds are compounds of the general formula I in which R1, R2, R3a, R3b, W, Y and X have the meanings mentioned in the claims and the description, the tautomers thereof and the pharmaceutically suitable salts thereof. In particular, the compounds have the general formula I-A.a? and I-A.a? in which m, E, R1, R3a, R3b, R2, Ry, Rw and Rw6*have the meanings mentioned in the claims, n is 0, 1 or 2, the tautomers thereof and the pharmaceutically suitable salts thereof.Type: GrantFiled: March 25, 2013Date of Patent: September 22, 2015Assignee: AbbVie Deutschland GmbH & Co. KGInventors: Andreas Kling, Wilfried Hornberger, Helmut Mack, Achim Moeller, Volker Nimmrich, Dietmar Seemann, Wilfried Lubisch
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Publication number: 20130245003Abstract: The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. The carboxamide compounds are compounds of the general formula I in which R1, R2, R3a, R3b, W, Y and X have the meanings mentioned in the claims and the description, the tautomers thereof and the pharmaceutically suitable salts thereof. In particular, the compounds have the general formula I-A.a? and I-A.a? in which m, E, R1, R3a, R3b, R2, Ry, Rw and Rw6* have the meanings mentioned in the claims, n is 0, 1 or 2, the tautomers thereof and the pharmaceutically suitable salts thereof.Type: ApplicationFiled: March 25, 2013Publication date: September 19, 2013Applicant: Abbott GmbH & Co. KGInventors: Andreas Kling, Wilfried Hornberger, Helmut Mack, Achim Moeller, Volker Nimmrich, Dietmar Seemann, Wilfried Lubisch
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Publication number: 20100298326Abstract: The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. The carboxamide compounds are compounds of the general formula I in which R1, R2, R3a, R3b, W, Y and X have the meanings mentioned in the claims and the description, the tautomers thereof and the pharmaceutically suitable salts thereof. In particular, the compounds have the general formula I-A.a? and I-A.a? in which m, E, R1, R3a, R3b, R2, Ry, Rw and Rw6* have the meanings mentioned in the claims, n is 0, 1 or 2, the tautomers thereof and the pharmaceutically suitable salts thereof.Type: ApplicationFiled: December 28, 2007Publication date: November 25, 2010Inventors: Andreas Kling, Wilfried Hornberger, Helmut Mack, Achim Moeller, Volker Nimmrich, Dietmar Seemann, Wilfried Lubisch
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Patent number: 7799809Abstract: The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. The carboxamide compounds are compounds of the general formula I in which R1, R2, R3a, R3b, W, Y and X have the meanings mentioned in the claims and the description, the tautomers thereof and the pharmaceutically suitable salts thereof. In particular, the compounds have the general formula I-A.a? and I-A.a? in which m, E, R1, R3a, R3b, R2, Ry, Rw and Rw6* have the meanings mentioned in the claims, n is 0, 1 or 2, the tautomers thereof and the pharmaceutically suitable salts thereof.Type: GrantFiled: February 22, 2008Date of Patent: September 21, 2010Assignee: Abbott GmbH & Co. KGInventors: Andreas Kling, Wilfried Hornberger, Helmut Mack, Achim Moeller, Volker Nimmrich, Dietmar Seemann, Wilfried Lubisch
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Patent number: 7728012Abstract: The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. The carboxamide compounds are compounds of the general formula I in which R1, R2, R3a, R3b, W, Y and X have the meanings mentioned in the claims and the description, the tautomers thereof and the pharmaceutically suitable salts thereof. In particular, the compounds have the general formula I-A.a? and I-A.a? in which m, E, R1, R3a, R3b, R2, Ry, Rw and Rw6* have the meanings mentioned in the claims, n is 0, 1 or 2, the tautomers thereof and the pharmaceutically suitable salts thereof.Type: GrantFiled: February 22, 2008Date of Patent: June 1, 2010Assignee: Abbott GmbH & Co. KGInventors: Andreas Kling, Wilfried Hornberger, Helmut Mack, Achim Moeller, Volker Nimmrich, Dietmar Seemann, Wilfried Lubisch
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Publication number: 20080234330Abstract: The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. The carboxamide compounds are compounds of the general formula I in which R1, R2, R3a, R3b, W, Y and X have the meanings mentioned in the claims and the description, the tautomers thereof and the pharmaceutically suitable salts thereof. In particular, the compounds have the general formula I-A.a? and I-A.a? in which m, E, R1, R3a, R3b, R2, Ry, Rw and Rw6* have the meanings mentioned in the claims, n is 0, 1 or 2, the tautomers thereof and the pharmaceutically suitable salts thereof.Type: ApplicationFiled: February 22, 2008Publication date: September 25, 2008Inventors: Andreas Kling, Wilfried Hornberger, Helmut Mack, Achim Moeller, Volker Nimmrich, Dietmar Seemann, Wilfried Lubisch
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Publication number: 20080234329Abstract: The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. The carboxamide compounds are compounds of the general formula I in which R1, R2, R3a, R3b, W, Y and X have the meanings mentioned in the claims and the description, the tautomers thereof and the pharmaceutically suitable salts thereof. In particular, the compounds have the general formula I-A.a? and I-A.a? in which m, E, R1, R3a, R3b, R2, Ry, Rw and Rw6* have the meanings mentioned in the claims, n is 0, 1 or 2, the tautomers thereof and the pharmaceutically suitable salts thereof.Type: ApplicationFiled: February 22, 2008Publication date: September 25, 2008Inventors: Andreas Kling, Wilfried Hornberger, Helmut Mack, Achim Moeller, Volker Nimmrich, Dietmar Seemann, Wilfried Lubisch
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Patent number: 5260318Abstract: Phenylpiperidylamines of the formula I ##STR1## R.sup.1 is H, NO.sub.2, R.sup.4 SO.sub.2 NH, ##STR2## N.dbd.C, CF.sub.3, CF.sub.3 O, F, Cl, Br, C.sub.1 -C.sub.4 -alkyl, R.sup.3 O, CO.sub.2 R.sup.3, CHO, CH.dbd.NOR.sup.3, CH.sub.3 OR.sup.3 andR.sup.2 is H, F, Cl, Br, C.sub.1 -C.sub.4 -alkyl or R.sup.4 O, where R.sup.1 and R.sup.2 are not both H,R.sup.3 is H or R.sup.4,R.sup.4 is C.sub.1 -C.sub.4 -alkyl or phenyl,n is 1, 2, 3 or 4 andAr is ##STR3## and the physiologically tolerated salts thereof, are used as active ingredients in drugs.Type: GrantFiled: September 16, 1991Date of Patent: November 9, 1993Assignee: BASF AktiengesellschaftInventors: Wilfried Lubisch, Sabine Schult, Rudolf Binder, Manfred Raschack, Roland Reinhardt, Dietmar Seemann
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Patent number: 5175174Abstract: Phenylpiperidinylamines of the formula I ##STR1## where R.sup.1 is --NHSO.sub.2 R.sup.4 or ##STR2## R.sup.2 and R.sup.3 are each, independently of one another, H or C.sub.1 -C.sub.4 -alkyl or together are a (CH.sub.2).sub.n chain with n=4 or 5, andR.sup.4 is C.sub.1 -C.sub.4 -alkyl or phenyl,and the physiologically tolerated salts thereof, and pharmaceutical compositions containing these are described.Type: GrantFiled: September 16, 1991Date of Patent: December 29, 1992Assignee: BASF AktiengesellschaftInventors: Wilfried Lubisch, Sabine Schult, Rudolf Binder, Manfred Raschack, Roland Reinhardt, Dietmar Seemann