Patents by Inventor Dietrich M. EGLI

Dietrich M. EGLI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HAPLOID HUMAN EMBRYONIC STEM CELL LINES AND SOMATIC CELL LINES AND METHODS OF MAKING THE SAME
    Publication number: 20210230539
    Abstract: Haploid human embryonic stem cells and cell lines, haploid multipotent human cells, and haploid differentiated human cells are provided. In addition, methods of making and using the haploid human cells are provided.
    Type: Application
    Filed: December 15, 2020
    Publication date: July 29, 2021
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Dietrich M. EGLI, Nissim BENVENISTY, Ido SAGI
  • METHODS FOR MAKING AND USING MODIFIED OOCYTES
    Publication number: 20210198697
    Abstract: The present invention provides modified oocytes having a nuclear genome derived from a first oocyte and cytoplasm derived from a second oocyte from a different subject, and methods for making and using such modified oocytes. The methods and compositions of the present invention can be useful in a variety of settings including, but not limited to, in in vitro fertilization (“IVF”) procedures.
    Type: Application
    Filed: March 15, 2021
    Publication date: July 1, 2021
    Inventor: Dietrich M. Egli
  • Haploid human embryonic stem cell lines and somatic cell lines and methods of making the same
    Patent number: 10961503
    Abstract: Haploid human embryonic stem cells and cell lines, haploid multipotent human cells, and haploid differentiated human cells are provided. In addition, methods of making and using the haploid human cells are provided.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: March 30, 2021
    Assignees: New York Stem Cell Foundation, Inc., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Dietrich M. Egli, Nissim Benvenisty, Ido Sagi
  • Methods for making and using modified oocytes
    Patent number: 10947562
    Abstract: The present invention provides modified oocytes having a nuclear genome derived from a first oocyte and cytoplasm derived from a second oocyte from a different subject, and methods for making and using such modified oocytes. The methods and compositions of the present invention can be useful in a variety of settings including, but not limited to, in in vitro fertilization (“IVF”) procedures.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: March 16, 2021
    Assignee: New York Stem Cell Foundation, Inc.
    Inventor: Dietrich M. Egli
  • Somatic cell nuclear transfer methods
    Patent number: 10513709
    Abstract: The present invention provides methods for making reconstructed diploid human oocytes comprising the diploid genome of a human somatic cell, and also methods for making human nuclear transfer embryos, human embryonic stem cells, and human differentiated cells therefrom. The present invention also provides reconstructed human oocytes, human nuclear transfer embryos, human embryonic stem cells, and differentiated cells made using such methods, as well as compositions and kits useful in performing such methods.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: December 24, 2019
    Assignee: New York Stem Cell Foundation, Inc.
    Inventor: Dietrich M. Egli
  • METHODS FOR MAKING AND USING MODIFIED OOCYTES
    Publication number: 20190338313
    Abstract: The present invention provides modified oocytes having a nuclear genome derived from a first oocyte and cytoplasm derived from a second oocyte from a different subject, and methods for making and using such modified oocytes. The methods and compositions of the present invention can be useful in a variety of settings including, but not limited to, in in vitro fertilization (“IVF”) procedures.
    Type: Application
    Filed: July 12, 2019
    Publication date: November 7, 2019
    Inventor: Dietrich M. Egli
  • Methods for making and using modified oocytes
    Patent number: 10351876
    Abstract: The present invention provides modified oocytes having a nuclear genome derived from a first oocyte and cytoplasm derived from a second oocyte from a different subject, and methods for making and using such modified oocytes. The methods and compositions of the present invention can be useful in a variety of settings including, but not limited to, in in vitro fertilization (“IVF”) procedures.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: July 16, 2019
    Assignee: New York Stem Cell Foundation, Inc.
    Inventor: Dietrich M. Egli
  • SOMATIC CELL NUCLEAR TRANSFER METHODS
    Publication number: 20180237799
    Abstract: The present invention provides methods for making reconstructed diploid human oocytes comprising the diploid genome of a human somatic cell, and also methods for making human nuclear transfer embryos, human embryonic stem cells, and human differentiated cells therefrom. The present invention also provides reconstructed human oocytes, human nuclear transfer embryos, human embryonic stem cells, and differentiated cells made using such methods, as well as compositions and kits useful in performing such methods.
    Type: Application
    Filed: February 13, 2018
    Publication date: August 23, 2018
    Inventor: Dietrich M. Egli
  • HAPLOID HUMAN EMBRYONIC STEM CELL LINES AND SOMATIC CELL LINES AND METHODS OF MAKING THE SAME
    Publication number: 20180208890
    Abstract: Haploid human embryonic stem cells and cell lines, haploid multipotent human cells, and haploid differentiated human cells are provided. In addition, methods of making and using the haploid human cells are provided.
    Type: Application
    Filed: July 28, 2016
    Publication date: July 26, 2018
    Inventors: Dietrich M. Egli, Nissim Benvenisty, Ido Sagi
  • Somatic cell nuclear transfer methods
    Patent number: 9896699
    Abstract: The present invention provides methods for making reconstructed diploid human oocytes comprising the diploid genome of a human somatic cell, and also methods for making human nuclear transfer embryos, human embryonic stem cells, and human differentiated cells therefrom. The present invention also provides reconstructed human oocytes, human nuclear transfer embryos, human embryonic stem cells, and differentiated cells made using such methods, as well as compositions and kits useful in performing such methods.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: February 20, 2018
    Assignee: New York Stem Cell Foundation, Inc.
    Inventor: Dietrich M. Egli
  • METHODS FOR MAKING AND USING MODIFIED OOCYTES
    Publication number: 20170114366
    Abstract: The present invention provides modified oocytes having a nuclear genome derived from a first oocyte and cytoplasm derived from a second oocyte from a different subject, and methods for making and using such modified oocytes. The methods and compositions of the present invention can be useful in a variety of settings including, but not limited to, in in vitro fertilization (“IVF”) procedures.
    Type: Application
    Filed: August 31, 2016
    Publication date: April 27, 2017
    Inventor: Dietrich M. Egli
  • Methods for making and using modified oocytes
    Patent number: 9434960
    Abstract: The present invention provides modified oocytes having a nuclear genome derived from a first oocyte and cytoplasm derived from a second oocyte from a different subject, and methods for making and using such modified oocytes. The methods and compositions of the present invention can be useful in a variety of settings including, but not limited to, in in vitro fertilization (“IVF”) procedures.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: September 6, 2016
    Assignee: New York Stem Cell Foundation, Inc.
    Inventor: Dietrich M. Egli
  • SOMATIC CELL NUCLEAR TRANSFER METHODS
    Publication number: 20160024528
    Abstract: The present invention provides methods for making reconstructed diploid human oocytes comprising the diploid genome of a human somatic cell, and also methods for making human nuclear transfer embryos, human embryonic stem cells, and human differentiated cells therefrom. The present invention also provides reconstructed human oocytes, human nuclear transfer embryos, human embryonic stem cells, and differentiated cells made using such methods, as well as compositions and kits useful in performing such methods.
    Type: Application
    Filed: March 14, 2014
    Publication date: January 28, 2016
    Inventor: Dietrich M. Egli
  • METHODS FOR MAKING AND USING MODIFIED OOCYTES
    Publication number: 20140308257
    Abstract: The present invention provides modified oocytes having a nuclear genome derived from a first oocyte and cytoplasm derived from a second oocyte from a different subject, and methods for making and using such modified oocytes. The methods and compositions of the present invention can be useful in a variety of settings including, but not limited to, in in vitro fertilization (“IVF”) procedures.
    Type: Application
    Filed: December 5, 2013
    Publication date: October 16, 2014
    Applicant: New York Stem Cell Foundation
    Inventor: Dietrich M. Egli
  • Method for producing pluripotent stem cells
    Patent number: 8748178
    Abstract: Methods are provided for producing a human embryo capable of developing to the blastocyst stage. The method includes transferring a human somatic cell genome into a mature human oocyte by nuclear transfer and activating the oocyte, without removing the oocyte genome. Pluripotent human embryonic stem cells, and methods of obtaining these, are also provided.
    Type: Grant
    Filed: November 22, 2011
    Date of Patent: June 10, 2014
    Assignee: The New York Stem Cell Foundation
    Inventors: Dietrich M. Egli, Scott A. Noggle, Kevin C. Eggan
  • METHOD FOR PRODUCING PLURIPOTENT STEM CELLS
    Publication number: 20120129260
    Abstract: Methods are provided for producing a human embryo capable of developing to the blastocyst stage. The method includes transferring a human somatic cell genome into a mature human oocyte by nuclear transfer and activating the oocyte, without removing the oocyte genome. Pluripotent human embryonic stem cells, and methods of obtaining these, are also provided.
    Type: Application
    Filed: November 22, 2011
    Publication date: May 24, 2012
    Applicant: THE NEW YORK STEM CELL FOUNDATION
    Inventors: Dietrich M. EGLI, Scott A. NOGGLE, Kevin C. EGGAN