Patents by Inventor Dietrich Rein

Dietrich Rein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11813302
    Abstract: The present invention provides transgenic Brassica events LBFLFK and LBFDAU and progeny thereof, and cells, seeds, plants comprising DNA diagnostic for these events. The invention also provides artificial oligonucleotide primers and probes that are diagnostic for the LBFLFK and LBFDAU events and their progeny in a sample, and methods for detecting the presence of the LBFLFK and LBFDAU events and their progeny in a sample. The invention further provides oil and commodity products derived from the LBFLFK and LBFDAU events.
    Type: Grant
    Filed: June 14, 2021
    Date of Patent: November 14, 2023
    Assignee: BASF PLANT SCIENCE COMPANY GMBH
    Inventors: Toralf Senger, Laurent Marty, Irene Kunze, Dietrich Rein, Jörg Bauer, Carl Andre
  • Publication number: 20230293615
    Abstract: T-DNA for expression of a target gene in a plant, wherein the T-DNA comprises a left and a right border element and at least one expression cassette comprising a promoter, operatively linked thereto a target gene, and downstream thereof a terminator, wherein the length of the T-DNA, measured from left to right border element and comprising the target gene, has a length of at least 30000 bp.
    Type: Application
    Filed: January 31, 2023
    Publication date: September 21, 2023
    Inventors: Toralf Senger, Laurent Marty, Irene Kunze, Heiko Haertel, Steven Craig Bremmer, Steven D. Breazeale, Joerg Bauer, Patricia Vrinten, Sten Stymne, Jenny Lindberg Yilmaz, John A. McElver, Dietrich Rein, Carl Andre
  • Patent number: 11613761
    Abstract: T-DNA for expression of a target gene in a plant, wherein the T-DNA comprises a left and a right border element and at least one expression cassette comprising a promoter, operatively linked thereto a target gene, and downstream thereof a terminator, wherein the length of the T-DNA, measured from left to right border element and comprising the target gene, has a length of at least 30000 bp.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: March 28, 2023
    Assignees: Bioriginal Food & Science Corporation, BASF Plant Science Company GmbH
    Inventors: Toralf Senger, Laurent Marty, Irene Kunze, Heiko Haertel, Steven Craig Bremmer, Steven D. Breazeale, Joerg Bauer, Patricia Vrinten, Sten Stymne, Jenny Lindberg Yilmaz, John A. McElver, Dietrich Rein, Carl Andre
  • Publication number: 20210308202
    Abstract: The present invention provides transgenic Brassica events LBFLFK and LBFDAU and progeny thereof, and cells, seeds, plants comprising DNA diagnostic for these events. The invention also provides artificial oligonucleotide primers and probes that are diagnostic for the LBFLFK and LBFDAU events and their progeny in a sample, and methods for detecting the presence of the LBFLFK and LBFDAU events and their progeny in a sample. The invention further provides oil and commodity products derived from the LBFLFK and LBFDAU events.
    Type: Application
    Filed: June 14, 2021
    Publication date: October 7, 2021
    Inventors: Toralf Senger, Laurent Marty, Irene Kunze, Dietrich Rein, Jörg Bauer, Carl Andre
  • Patent number: 11033593
    Abstract: The present invention provides transgenic Brassica events LBFLFK and LBFDAU and progeny thereof, and cells, seeds, plants comprising DNA diagnostic for these events. The invention also provides artificial oligonucleotide primers and probes that are diagnostic for the LBFLFK and LBFDAU events and their progeny in a sample, and methods for detecting the presence of the LBFLFK and LBFDAU events and their progeny in a sample. The invention further provides oil and commodity products derived from the LBFLFK and LBFDAU events.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: June 15, 2021
    Assignee: BASF PLANT SCIENCE COMPANY GMBH
    Inventors: Toralf Senger, Laurent Marty, Irene Kunze, Dietrich Rein, Joerg Bauer, Carl Andre
  • Publication number: 20180298400
    Abstract: The present invention provides transgenic Brassica events LBFLFK and LBFDAU and progeny thereof, and cells, seeds, plants comprising DNA diagnostic for these events. The invention also provides artificial oligonucleotide primers and probes that are diagnostic for the LBFLFK and LBFDAU events and their progeny in a sample, and methods for detecting the presence of the LBFLFK and LBFDAU events and their progeny in a sample. The invention further provides oil and commodity products derived from the LBFLFK and LBFDAU events.
    Type: Application
    Filed: November 13, 2015
    Publication date: October 18, 2018
    Inventors: Toralf SENGER, Laurent MARTY, Irene KUNZE, Dietrich REIN, Joerg BAUER, Carl ANDRE
  • Publication number: 20180267018
    Abstract: The present invention provides biomarkers and a method for diagnosing a liver disease in a subject such as steatosis, inflammatory liver disease, NASH, and NAFLD. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.
    Type: Application
    Filed: May 18, 2018
    Publication date: September 20, 2018
    Applicants: METANOMICS HEALTH GMBH, Universitätsklinikum Schleswig-Holstein
    Inventors: Hennicke Kamp, Ulrike Rennefahrt, Jens Fuhrmann, Dietrich Rein, Jochen Hampe, Clemens Schafmayer
  • Patent number: 10001468
    Abstract: The present invention provides biomarkers and a method for differentiating between NASH and NAFLD in a subject.
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: June 19, 2018
    Assignees: METANOMICS HEALTH GMBH, UNIVERSITATSKLINIKUM SCHLESWIG-HOLSTEIN
    Inventors: Hennicke Kamp, Ulrike Rennefahrt, Jens Fuhrmann, Dietrich Rein, Jochen Hampe, Clemens Schafmayer
  • Publication number: 20150355197
    Abstract: The present invention provides biomarkers and a method for diagnosing a liver disease in a subject such as steatosis, inflammatory liver disease, NASH, and NAFLD. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.
    Type: Application
    Filed: August 18, 2015
    Publication date: December 10, 2015
    Applicants: Universitätsklinikum Schleswig-Holstein, METANOMICS HEALTH GMBH
    Inventors: Hennicke Kamp, Ulrike Rennefahrt, Jens Fuhrmann, Dietrich Rein, Jochen Hampe, Clemens Schafmayer
  • Patent number: 9140686
    Abstract: The present invention provides biomarkers and a method for diagnosing a liver disease in a subject such as steatosis, inflammatory liver disease, NASH, and NAFLD. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.
    Type: Grant
    Filed: June 10, 2011
    Date of Patent: September 22, 2015
    Assignees: Metanomics Health GmbH, Universitätsklinikum Schleswig-Holstein
    Inventors: Hennicke Kamp, Ulrike Rennefahrt, Jens Fuhrmann, Dietrich Rein, Jochen Hampe, Clemens Schafmayer
  • Publication number: 20150204851
    Abstract: The present invention relates to screening methods for diabetes drugs. In particular, the invention concerns a method for identifying a drug against diabetes comprising determining the amount of glyoxylate in a test sample of a subject suffering from diabetes or a diabetes-like condition, wherein said test sample has been taken after the subject has been brought into contact with a compound suspected to be a drug against diabetes and comparing the determined amount to a reference amount for glyoxylate, whereby a compound being a drug against diabetes is identified.
    Type: Application
    Filed: June 27, 2013
    Publication date: July 23, 2015
    Applicant: Metanomics Health GmbH
    Inventors: Dietrich Rein, Victoria Nikiforova, Inken Padberg, Volker Liebenberg
  • Publication number: 20140030744
    Abstract: The present invention relates to the field of diagnostic measures. Specifically, it contemplates a method for assessing whether gastric bypass therapy was successful in a subject, a method of predicting whether gastric bypass therapy will be beneficial for a subject in need thereof, and a method of diagnosing whether a supportive therapy accompanying gastric bypass has beneficial effects on a subject in need thereof. Further provided are diagnostic methods for diabetes and body lean mass. Furthermore, the invention relates to a method for identifying a treatment against diabetes and/or obesity.
    Type: Application
    Filed: September 30, 2013
    Publication date: January 30, 2014
    Applicants: INSERM Institute National de la Sante et de la Recherche Medicale, Metanomics GmbH
    Inventors: Jens Fuhrmann, Dietrich Rein, Beate Kamlage, Jan C. Wiemer, Michael Manfred Herold, Karine Clément, David M. Mutch
  • Publication number: 20130295692
    Abstract: A method for diagnosing diabetes or a predisposition for diabetes is provided, which comprises determining the amount of glyoxylate in a test sample of a subject suspected to suffer from diabetes or to have a predisposition for diabetes and comparing said amount to a references, whereby diabetes or a predisposition for diabetes is to be diagnosed. Further, the use of glyoxylate or a detection agent for glyoxylate for diagnosing diabetes or a predisposition for diabetes is provided. Moreover, a device and a kit for diagnosing diabetes or a predisposition for diabetes are also provided.
    Type: Application
    Filed: December 23, 2011
    Publication date: November 7, 2013
    Applicant: METANOMICS HEALTH GMBH
    Inventors: Jan C. Wiemer, Dietrich Rein, Inken Padberg, Oliver Schmitz, Volker Liebenberg, Victoria Nikiforova
  • Patent number: 8455035
    Abstract: The invention relates to a plant seed oil, comprising arachidonic acid comprising approximately 7 to approximately 26 percent by weight of the total fatty acid content, the ratio of the percentages by weight of arachidonic acid to gamma-linolenic acid being approximately 1:1 to approximately 5:1 and the ratio of the percentages by weight of arachidonic acid to dihomo-gamma-linolenic acid being approximately 1:1 to approximately 5:1. The invention additionally relates to processes for the production of this plant seed oil and formulations and uses of the plant seed oil. In particular, the invention also makes available foodstuffs and baby food that contain the plant seed oil mentioned.
    Type: Grant
    Filed: April 23, 2009
    Date of Patent: June 4, 2013
    Assignee: BASF Plant Science GmbH
    Inventors: Dietrich Rein, Toralf Senger, Jörg Bauer
  • Publication number: 20130126722
    Abstract: The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing a liver disease in a subject and a method of differentiating between NASH and NAFLD. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.
    Type: Application
    Filed: June 10, 2011
    Publication date: May 23, 2013
    Applicant: Metanomics Health GmbH
    Inventors: Hennicke Kamp, Ulrike Rennefahrt, Jens Fuhrmann, Dietrich Rein, Jochen Hampe, Clemens Schafmayer
  • Publication number: 20110113863
    Abstract: The present invention relates to the field of diagnostic measures. Specifically, it contemplates a method for assessing whether gastric bypass therapy was successful in a subject, a method of predicting whether gastric bypass therapy will be beneficial for a subject in need thereof, and a method of diagnosing whether a supportive therapy accompanying gastric bypass has beneficial effects on a subject in need thereof. Further provided are diagnostic methods for diabetes and body lean mass. Furthermore, the invention relates to a method for identifying a treatment against diabetes and/or obesity.
    Type: Application
    Filed: July 15, 2009
    Publication date: May 19, 2011
    Applicants: Metanomics Health GmbH, INSERM Institute National de la Sante' et de la Recherche Medicale
    Inventors: Jens Fuhrmann, Dietrich Rein, Beate Kamlage, Jan C. Wiemer, Michael Manfred Herold, Karine Clément, David M. Mutch
  • Publication number: 20110039010
    Abstract: The invention relates to a plant seed oil, comprising arachidonic acid comprising approximately 7 to approximately 26 percent by weight of the total fatty acid content, the ratio of the percentages by weight of arachidonic acid to gamma-linolenic acid being approximately 1:1 to approximately 5:1 and the ratio of the percentages by weight of arachidonic acid to dihomo-gamma-linolenic acid being approximately 1:1 to approximately 5:1. The invention additionally relates to processes for the production of this plant seed oil and formulations and uses of the plant seed oil. In particular, the invention also makes available foodstuffs and baby food that contain the plant seed oil mentioned.
    Type: Application
    Filed: April 23, 2009
    Publication date: February 17, 2011
    Applicant: BASF Plant Science GmbH
    Inventors: Dietrich Rein, Toralf Senger, Jörg Bauer