Patents by Inventor Dietrich Rein
Dietrich Rein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11813302Abstract: The present invention provides transgenic Brassica events LBFLFK and LBFDAU and progeny thereof, and cells, seeds, plants comprising DNA diagnostic for these events. The invention also provides artificial oligonucleotide primers and probes that are diagnostic for the LBFLFK and LBFDAU events and their progeny in a sample, and methods for detecting the presence of the LBFLFK and LBFDAU events and their progeny in a sample. The invention further provides oil and commodity products derived from the LBFLFK and LBFDAU events.Type: GrantFiled: June 14, 2021Date of Patent: November 14, 2023Assignee: BASF PLANT SCIENCE COMPANY GMBHInventors: Toralf Senger, Laurent Marty, Irene Kunze, Dietrich Rein, Jörg Bauer, Carl Andre
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Publication number: 20230293615Abstract: T-DNA for expression of a target gene in a plant, wherein the T-DNA comprises a left and a right border element and at least one expression cassette comprising a promoter, operatively linked thereto a target gene, and downstream thereof a terminator, wherein the length of the T-DNA, measured from left to right border element and comprising the target gene, has a length of at least 30000 bp.Type: ApplicationFiled: January 31, 2023Publication date: September 21, 2023Inventors: Toralf Senger, Laurent Marty, Irene Kunze, Heiko Haertel, Steven Craig Bremmer, Steven D. Breazeale, Joerg Bauer, Patricia Vrinten, Sten Stymne, Jenny Lindberg Yilmaz, John A. McElver, Dietrich Rein, Carl Andre
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Patent number: 11613761Abstract: T-DNA for expression of a target gene in a plant, wherein the T-DNA comprises a left and a right border element and at least one expression cassette comprising a promoter, operatively linked thereto a target gene, and downstream thereof a terminator, wherein the length of the T-DNA, measured from left to right border element and comprising the target gene, has a length of at least 30000 bp.Type: GrantFiled: November 13, 2015Date of Patent: March 28, 2023Assignees: Bioriginal Food & Science Corporation, BASF Plant Science Company GmbHInventors: Toralf Senger, Laurent Marty, Irene Kunze, Heiko Haertel, Steven Craig Bremmer, Steven D. Breazeale, Joerg Bauer, Patricia Vrinten, Sten Stymne, Jenny Lindberg Yilmaz, John A. McElver, Dietrich Rein, Carl Andre
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Publication number: 20210308202Abstract: The present invention provides transgenic Brassica events LBFLFK and LBFDAU and progeny thereof, and cells, seeds, plants comprising DNA diagnostic for these events. The invention also provides artificial oligonucleotide primers and probes that are diagnostic for the LBFLFK and LBFDAU events and their progeny in a sample, and methods for detecting the presence of the LBFLFK and LBFDAU events and their progeny in a sample. The invention further provides oil and commodity products derived from the LBFLFK and LBFDAU events.Type: ApplicationFiled: June 14, 2021Publication date: October 7, 2021Inventors: Toralf Senger, Laurent Marty, Irene Kunze, Dietrich Rein, Jörg Bauer, Carl Andre
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Patent number: 11033593Abstract: The present invention provides transgenic Brassica events LBFLFK and LBFDAU and progeny thereof, and cells, seeds, plants comprising DNA diagnostic for these events. The invention also provides artificial oligonucleotide primers and probes that are diagnostic for the LBFLFK and LBFDAU events and their progeny in a sample, and methods for detecting the presence of the LBFLFK and LBFDAU events and their progeny in a sample. The invention further provides oil and commodity products derived from the LBFLFK and LBFDAU events.Type: GrantFiled: November 13, 2015Date of Patent: June 15, 2021Assignee: BASF PLANT SCIENCE COMPANY GMBHInventors: Toralf Senger, Laurent Marty, Irene Kunze, Dietrich Rein, Joerg Bauer, Carl Andre
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Publication number: 20180298400Abstract: The present invention provides transgenic Brassica events LBFLFK and LBFDAU and progeny thereof, and cells, seeds, plants comprising DNA diagnostic for these events. The invention also provides artificial oligonucleotide primers and probes that are diagnostic for the LBFLFK and LBFDAU events and their progeny in a sample, and methods for detecting the presence of the LBFLFK and LBFDAU events and their progeny in a sample. The invention further provides oil and commodity products derived from the LBFLFK and LBFDAU events.Type: ApplicationFiled: November 13, 2015Publication date: October 18, 2018Inventors: Toralf SENGER, Laurent MARTY, Irene KUNZE, Dietrich REIN, Joerg BAUER, Carl ANDRE
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Publication number: 20180267018Abstract: The present invention provides biomarkers and a method for diagnosing a liver disease in a subject such as steatosis, inflammatory liver disease, NASH, and NAFLD. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.Type: ApplicationFiled: May 18, 2018Publication date: September 20, 2018Applicants: METANOMICS HEALTH GMBH, Universitätsklinikum Schleswig-HolsteinInventors: Hennicke Kamp, Ulrike Rennefahrt, Jens Fuhrmann, Dietrich Rein, Jochen Hampe, Clemens Schafmayer
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Patent number: 10001468Abstract: The present invention provides biomarkers and a method for differentiating between NASH and NAFLD in a subject.Type: GrantFiled: August 18, 2015Date of Patent: June 19, 2018Assignees: METANOMICS HEALTH GMBH, UNIVERSITATSKLINIKUM SCHLESWIG-HOLSTEINInventors: Hennicke Kamp, Ulrike Rennefahrt, Jens Fuhrmann, Dietrich Rein, Jochen Hampe, Clemens Schafmayer
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Publication number: 20150355197Abstract: The present invention provides biomarkers and a method for diagnosing a liver disease in a subject such as steatosis, inflammatory liver disease, NASH, and NAFLD. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.Type: ApplicationFiled: August 18, 2015Publication date: December 10, 2015Applicants: Universitätsklinikum Schleswig-Holstein, METANOMICS HEALTH GMBHInventors: Hennicke Kamp, Ulrike Rennefahrt, Jens Fuhrmann, Dietrich Rein, Jochen Hampe, Clemens Schafmayer
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Patent number: 9140686Abstract: The present invention provides biomarkers and a method for diagnosing a liver disease in a subject such as steatosis, inflammatory liver disease, NASH, and NAFLD. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.Type: GrantFiled: June 10, 2011Date of Patent: September 22, 2015Assignees: Metanomics Health GmbH, Universitätsklinikum Schleswig-HolsteinInventors: Hennicke Kamp, Ulrike Rennefahrt, Jens Fuhrmann, Dietrich Rein, Jochen Hampe, Clemens Schafmayer
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Publication number: 20150204851Abstract: The present invention relates to screening methods for diabetes drugs. In particular, the invention concerns a method for identifying a drug against diabetes comprising determining the amount of glyoxylate in a test sample of a subject suffering from diabetes or a diabetes-like condition, wherein said test sample has been taken after the subject has been brought into contact with a compound suspected to be a drug against diabetes and comparing the determined amount to a reference amount for glyoxylate, whereby a compound being a drug against diabetes is identified.Type: ApplicationFiled: June 27, 2013Publication date: July 23, 2015Applicant: Metanomics Health GmbHInventors: Dietrich Rein, Victoria Nikiforova, Inken Padberg, Volker Liebenberg
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Publication number: 20140030744Abstract: The present invention relates to the field of diagnostic measures. Specifically, it contemplates a method for assessing whether gastric bypass therapy was successful in a subject, a method of predicting whether gastric bypass therapy will be beneficial for a subject in need thereof, and a method of diagnosing whether a supportive therapy accompanying gastric bypass has beneficial effects on a subject in need thereof. Further provided are diagnostic methods for diabetes and body lean mass. Furthermore, the invention relates to a method for identifying a treatment against diabetes and/or obesity.Type: ApplicationFiled: September 30, 2013Publication date: January 30, 2014Applicants: INSERM Institute National de la Sante et de la Recherche Medicale, Metanomics GmbHInventors: Jens Fuhrmann, Dietrich Rein, Beate Kamlage, Jan C. Wiemer, Michael Manfred Herold, Karine Clément, David M. Mutch
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Publication number: 20130295692Abstract: A method for diagnosing diabetes or a predisposition for diabetes is provided, which comprises determining the amount of glyoxylate in a test sample of a subject suspected to suffer from diabetes or to have a predisposition for diabetes and comparing said amount to a references, whereby diabetes or a predisposition for diabetes is to be diagnosed. Further, the use of glyoxylate or a detection agent for glyoxylate for diagnosing diabetes or a predisposition for diabetes is provided. Moreover, a device and a kit for diagnosing diabetes or a predisposition for diabetes are also provided.Type: ApplicationFiled: December 23, 2011Publication date: November 7, 2013Applicant: METANOMICS HEALTH GMBHInventors: Jan C. Wiemer, Dietrich Rein, Inken Padberg, Oliver Schmitz, Volker Liebenberg, Victoria Nikiforova
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Patent number: 8455035Abstract: The invention relates to a plant seed oil, comprising arachidonic acid comprising approximately 7 to approximately 26 percent by weight of the total fatty acid content, the ratio of the percentages by weight of arachidonic acid to gamma-linolenic acid being approximately 1:1 to approximately 5:1 and the ratio of the percentages by weight of arachidonic acid to dihomo-gamma-linolenic acid being approximately 1:1 to approximately 5:1. The invention additionally relates to processes for the production of this plant seed oil and formulations and uses of the plant seed oil. In particular, the invention also makes available foodstuffs and baby food that contain the plant seed oil mentioned.Type: GrantFiled: April 23, 2009Date of Patent: June 4, 2013Assignee: BASF Plant Science GmbHInventors: Dietrich Rein, Toralf Senger, Jörg Bauer
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Publication number: 20130126722Abstract: The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing a liver disease in a subject and a method of differentiating between NASH and NAFLD. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.Type: ApplicationFiled: June 10, 2011Publication date: May 23, 2013Applicant: Metanomics Health GmbHInventors: Hennicke Kamp, Ulrike Rennefahrt, Jens Fuhrmann, Dietrich Rein, Jochen Hampe, Clemens Schafmayer
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Publication number: 20110113863Abstract: The present invention relates to the field of diagnostic measures. Specifically, it contemplates a method for assessing whether gastric bypass therapy was successful in a subject, a method of predicting whether gastric bypass therapy will be beneficial for a subject in need thereof, and a method of diagnosing whether a supportive therapy accompanying gastric bypass has beneficial effects on a subject in need thereof. Further provided are diagnostic methods for diabetes and body lean mass. Furthermore, the invention relates to a method for identifying a treatment against diabetes and/or obesity.Type: ApplicationFiled: July 15, 2009Publication date: May 19, 2011Applicants: Metanomics Health GmbH, INSERM Institute National de la Sante' et de la Recherche MedicaleInventors: Jens Fuhrmann, Dietrich Rein, Beate Kamlage, Jan C. Wiemer, Michael Manfred Herold, Karine Clément, David M. Mutch
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Publication number: 20110039010Abstract: The invention relates to a plant seed oil, comprising arachidonic acid comprising approximately 7 to approximately 26 percent by weight of the total fatty acid content, the ratio of the percentages by weight of arachidonic acid to gamma-linolenic acid being approximately 1:1 to approximately 5:1 and the ratio of the percentages by weight of arachidonic acid to dihomo-gamma-linolenic acid being approximately 1:1 to approximately 5:1. The invention additionally relates to processes for the production of this plant seed oil and formulations and uses of the plant seed oil. In particular, the invention also makes available foodstuffs and baby food that contain the plant seed oil mentioned.Type: ApplicationFiled: April 23, 2009Publication date: February 17, 2011Applicant: BASF Plant Science GmbHInventors: Dietrich Rein, Toralf Senger, Jörg Bauer