Patents by Inventor Dilinie P. Fernando

Dilinie P. Fernando has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2,3-DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.5]NONANE DERIVATIVES
    Publication number: 20140080756
    Abstract: The present invention provides a compound of Formula (I) a pharmaceutically salt thereof wherein R1, R2, Ra, L, Z, Z1 and Z2 are as defined herein, that act as Ghrelin antagonists or inverse agonists; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by the antagonism of the Ghrelin receptor.
    Type: Application
    Filed: November 18, 2013
    Publication date: March 20, 2014
    Applicant: Pfizer Inc.
    Inventors: Samit K. Bhattacharya, Kimberly O. Cameron, Dilinie P. Fernando, Kim F. McClure, Daniel W. Kung, Allyn T. Londregan, Suvi T.M. Orr
  • 2,3-dihydro-1H-inden-1-yl-2,7-diazaspiro[3.5] nonane derivatives
    Patent number: 8609680
    Abstract: The present invention provides a compound of Formula (I) or a pharmaceutically salt thereof wherein R1, R2, Ra, L, Z, Z1 and Z2 are as defined herein, that act as Ghrelin antagonists or inverse agonists; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by the antagonism of the Ghrelin receptor.
    Type: Grant
    Filed: March 16, 2011
    Date of Patent: December 17, 2013
    Assignee: Pfizer Inc.
    Inventors: Samit K. Bhattacharya, Kimberly O. Cameron, Dilinie P. Fernando, Kim F. McClure, Daniel W. Kung, Allyn T. Londregan, Suvi T. M. Simila
  • Process for the preparation of indazolyl ureas that inhibit Vanilloid subtype 1 (VR1) receptors
    Patent number: 8519186
    Abstract: The present invention relates to a process of preparing indazolyl ureas that are useful as antagonists of the vanilloid receptor subtype 1 (VR1).
    Type: Grant
    Filed: October 28, 2010
    Date of Patent: August 27, 2013
    Assignee: AbbVie Inc.
    Inventors: Kirill A. Lukin, Margaret Chi-Ping Hsu, Dilinie P. Fernando, Brian J. Kotecki, Marvin R. Leanna
  • Fused Bicyclic-Substituted Amines as Histamine-3 Receptor Ligands
    Publication number: 20120108637
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands and methods for using such compounds and compositions.
    Type: Application
    Filed: December 22, 2011
    Publication date: May 3, 2012
    Applicant: Abbott Laboratories
    Inventors: Marlon D. COWART, Yi-Yin Ku, Sou-Jen Chang, Dilinie P. Fernando, Timothy A. Grieme, Robert J. Altenbach
  • Fused bicyclic-substituted amines as histamine-3 receptor ligands
    Patent number: 8106088
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands and methods for using such compounds and compositions.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: January 31, 2012
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Yi-Yin Ku, Sou-Jen Chang, Dilinie P. Fernando, Timothy A. Grieme, Robert J. Altenbach
  • 2,3-DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.5] NONANE DERIVATIVES
    Publication number: 20110230461
    Abstract: The present invention provides a compound of Formula (I) or a pharmaceutically salt thereof wherein R1, R2, Ra, L, Z, Z1 and Z2 are as defined herein, that act as Ghrelin antagonists or inverse agonists; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by the antagonism of the Ghrelin receptor.
    Type: Application
    Filed: March 16, 2011
    Publication date: September 22, 2011
    Inventors: Samit K. Bhattacharya, Kimberly O. Cameron, Dilinie P. Fernando, Kim F. McClure, Daniel W. Kung, Allyn T. Londregan, Suvi T. M. Simila
  • ANTAGONISTS OF THE VANILLOID RECEPTOR SUBTYPE 1 (VR1) AND USE THEREOF
    Publication number: 20110144057
    Abstract: The present invention is directed to compounds of formula (I) wherein variables W, X, Y, D, A, n, R1, R2 and R9 are as defined in the description.
    Type: Application
    Filed: February 8, 2011
    Publication date: June 16, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Arthur Gomtsyan, Richard J. Perner, John R. Koenig, Margaret Chi-Ping Hsu, Dilinie P. Fernando, Chih-Hung Lee
  • Process for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane-carboxylates
    Patent number: 7956195
    Abstract: The present invention discloses processes for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane-carboxylates.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: June 7, 2011
    Assignee: Abbott Laboratories
    Inventors: Thomas D. Gordon, Grier A. Wallace, Martin E. Hayes, Kirill A. Lukin, Lei Wang, Dilinie P. Fernando
  • Spirocyclopropyl amides and acids and their therapeutic applications
    Patent number: 7932245
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of epilepsy, bipolar disorder, psychiatric disorders, migraine, pain, or movement disorders, and to provide neuroprotection.
    Type: Grant
    Filed: October 22, 2003
    Date of Patent: April 26, 2011
    Assignee: Abbott Laboratories
    Inventors: Youssef L. Bennani, William H. Bunnelle, Sou-Jen Chang, Sanjay R. Chemburkar, Jinhua Chen, Michael J. Dart, Dilinie P. Fernando, Yi-Yin Ku, Mark Lockwood, Lei Wang
  • Antagonists of the vanilloid receptor subtype 1 (VR1) and use thereof
    Patent number: 7902236
    Abstract: The present invention is directed to compounds of formula (I) wherein variables W, X, Y, D, A, n, R1, R2 and R9 are as defined in the description.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: March 8, 2011
    Assignee: Abbott Laboratories
    Inventors: Arthur Gomtsyan, Richard J. Perner, John R. Koenig, Margaret Chi-Ping Hsu, Dilinie P. Fernando, Chih-Hung Lee
  • PROCESS FOR THE PREPARATION OF INDAZOLYL UREAS THAT INHIBIT VANILLOID SUBTYPE 1 (VR1) RECEPTORS
    Publication number: 20110040102
    Abstract: The present invention relates to a process of preparing indazolyl ureas that are useful as antagonists of the vanilloid receptor subtype 1 (VR1).
    Type: Application
    Filed: October 28, 2010
    Publication date: February 17, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Kirill A. Lukin, Margaret Chi-Ping Hsu, Dilinie P. Fernando, Brian J. Kotecki, Marvin R. Leanna
  • Process for the preparation of indazolyl ureas that inhibit Vanilloid subtype1 (VR1) receptors
    Patent number: 7847104
    Abstract: The present invention relates to a process of preparing indazolyl ureas that are useful as antagonists of the vanilloid receptor subtype 1 (VR1).
    Type: Grant
    Filed: April 13, 2007
    Date of Patent: December 7, 2010
    Assignee: Abbott Laboratories
    Inventors: Kirill A. Lukin, Margaret Chi-Ping Hsu, Dilinie P. Fernando, Brian J. Kotecki, Marvin R. Leanna
  • FUSED BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS
    Publication number: 20100298291
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands and methods for using such compounds and compositions.
    Type: Application
    Filed: July 30, 2010
    Publication date: November 25, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Marlon D. Cowart, Yi-Yin Ku, Sou-Jen Chang, Dilinie P. Fernando, Timothy A. Grieme, Robert J. Altenbach
  • Fused bicyclic-substituted amines as histamine-3 receptor ligands
    Patent number: 7807697
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands and methods for using such compounds and compositions.
    Type: Grant
    Filed: January 29, 2008
    Date of Patent: October 5, 2010
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Yi-Yin Ku, Sou-Jen Chang, Dilinie P. Fernando, Timothy A. Grieme, Robert J. Altenbach
  • ANTAGONISTS OF THE VANILLOID RECEPTOR SUBTYPE 1 (VR1) AND USE THEREOF
    Publication number: 20100010055
    Abstract: The present invention is directed to compounds of formula (I) wherein variables W, X, Y, D, A, n, R1, R2 and R9 are as defined in the description.
    Type: Application
    Filed: February 4, 2009
    Publication date: January 14, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Arthur Gomtsyan, Richard J. Perner, John R. Koenig, Margaret Chi-Ping Hsu, Dilinie P. Fernando, Chih-Hung Lee
  • Antagonists of the vanilloid receptor subtype 1 (VR1) and use thereof
    Patent number: 7504520
    Abstract: The present invention is directed to compounds of formula (I) wherein variables W, X, Y, D, A, n, R1, R2 and R9 are as defined in the description.
    Type: Grant
    Filed: May 10, 2006
    Date of Patent: March 17, 2009
    Assignee: Abbott Laboratories
    Inventors: Arthur Gomtsyan, Richard J. Perner, John R. Koenig, Margaret Chi-Ping Hsu, Dilinie P. Fernando, Chih-Hung Lee
  • Process for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane-carboxylates
    Publication number: 20080255367
    Abstract: The present invention discloses processes for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane-carboxylates.
    Type: Application
    Filed: December 21, 2007
    Publication date: October 16, 2008
    Inventors: Thomas D. Gordon, Grier A. Wallace, Martin E. Hayes, Kirill A. Lukin, Lei Wang, Dilinie P. Fernando
  • Fused bicyclic-substituted amines as histamine-3 receptor ligands
    Patent number: 7358263
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands and methods for using such compounds and compositions.
    Type: Grant
    Filed: February 16, 2006
    Date of Patent: April 15, 2008
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Yi-Yin Ku, Sou-Jen Chang, Dilinie P. Fernando
  • Fused bicyclic-substituted amines as histamine-3 receptor ligands
    Patent number: 7094790
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands and methods for using such compounds and compositions.
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: August 22, 2006
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Yi-Yin Ku, Sou-Jen Chang, Dilinie P. Fernando, Timothy A. Grieme, Robert J. Altenbach
  • Fused bicyclic-substituted amines as histamine-3 receptor ligands
    Publication number: 20040248899
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: April 30, 2004
    Publication date: December 9, 2004
    Inventors: Marlon D. Cowart, Yi-Yin Ku, Sou-Jen Chang, Dilinie P. Fernando, Timothy A. Grieme, Robert J. Altenbach