Patents by Inventor Dimitri Gaitanopoulos

Dimitri Gaitanopoulos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphate transport inhibitors
    Publication number: 20030216449
    Abstract: N-Aryl-2-sulfonamidobenzamides, useful for treatment of chronic renal failure and uremic bone disease, are disclosed.
    Type: Application
    Filed: November 8, 2002
    Publication date: November 20, 2003
    Inventors: Joseph Weinstock, Gerald Girard, Dimitri Gaitanopoulos
  • Phosphate transport inhibitors
    Publication number: 20030212074
    Abstract: Dihydroxybenzamides, useful for treatment of chronic renal failure and uremic bone disease, are disclosed.
    Type: Application
    Filed: October 29, 2002
    Publication date: November 13, 2003
    Inventors: Dimitri Gaitanopoulos, Gerald R. Girard, Joseph Weinstock
  • Fatty acid synthase inhibitors
    Patent number: 6559179
    Abstract: This invention relates to the use of compounds as inhibitors of the fatty acid synthase FabH.
    Type: Grant
    Filed: February 5, 2002
    Date of Patent: May 6, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Dimitri Gaitanopoulos, Jack D. Leber, Mei Li, Joseph Weinstock
  • Carbamates of 6-chloro-7,8-dihydroxy-1-(4'-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benz azepine as prodrugs
    Patent number: 4861771
    Abstract: Prodrug carbamate derivatives of fenoldopam which provide fenoldopam plasma levels of similar magnitude and over a much longer period of time than the parent compound. An absence of a high initial peak effect associated with the parent compound is noted. A lead compound of the series is 6-chloro-7,8-diethylcarbamoyl-1-(4'-ethylcarbamoylphenyl)-2,3,4,5-tetrahyd ro-1H-3-benzazepine. The R-enantiomers are the most biologically active and preferred compounds.
    Type: Grant
    Filed: January 27, 1989
    Date of Patent: August 29, 1989
    Assignee: SmithKline Beckman Corporation
    Inventors: Dimitri Gaitanopoulos, Bruce Mico, Joseph Weinstock
  • Fenoldopam 4',8-bis-hydrogen sulfate and dopaminergic use thereof
    Patent number: 4600714
    Abstract: Fenoldopam 4',8-bis-hydrogen sulfate and its salts are useful prodrugs to obtain extended dopaminergic activity. A useful species is the monoammonium salt.
    Type: Grant
    Filed: April 26, 1984
    Date of Patent: July 15, 1986
    Assignee: SmithKline Beckman Corporation
    Inventors: Dimitri Gaitanopoulos, Joseph Weinstock
  • 3-Carboxy-2-azabicyclo[2.2.1]heptane derivatives
    Patent number: 4405787
    Abstract: 3-Carboxy-2-(.omega.-carboxyalkanoyl)-2-azabicyclo-[2.2.1]heptenes have been demonstrated to improve kidney function. 3-Carboxy-2-azabicyclo[2.2.1]heptane and its esters are important new chemical intermediates.
    Type: Grant
    Filed: April 5, 1982
    Date of Patent: September 20, 1983
    Assignee: SmithKline Beckman Corporation
    Inventors: Dimitri Gaitanopoulos, Joseph Weinstock