Patents by Inventor Dimitri M. KULLMANN

Dimitri M. KULLMANN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression vectors comprising engineered genes
    Patent number: 11779658
    Abstract: The invention provides expression vectors, nucleic acids, vector particles and methods of treatment involving these vector particles, comprising an engineered KCNA1 gene encoding an edited Kv1.1 potassium channel, as well as methods of confirming the presence of engineered KCNA1 mRNA in a cell. The features of the engineered KCNA1 gene combine to advantageously enhance the translation and activity of the Kv1.1 protein and improve detection of KCNA1 gene expression in a cell and can be used for example in the treatment of epilepsy and similar neurological disorders.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: October 10, 2023
    Assignee: UCL BUSINESS LTD
    Inventors: Stephanie Schorge, Matthew Charles Walker, Dimitri M. Kullmann, Albert Snowball, Elodie Chabrol
  • EXPRESSION VECTORS COMPRISING ENGINEERED GENES
    Publication number: 20210000977
    Abstract: The invention provides expression vectors, nucleic acids, vector particles and methods of treatment involving these vector particles, comprising an engineered KCNA1 gene encoding an edited Kv1.1 potassium channel, as well as methods of confirming the presence of engineered KCNA1 mRNA in a cell. The features of the engineered KCNA1 gene combine to advantageously enhance the translation and activity of the Kv1.1 protein and improve detection of KCNA1 gene expression in a cell and can be used for example in the treatment of epilepsy and similar neurological disorders.
    Type: Application
    Filed: June 15, 2018
    Publication date: January 7, 2021
    Applicant: UCL BUSINESS PLC
    Inventors: Stephanie SCHORGE, Matthew Charles WALKER, Dimitri M. KULLMANN, Albert SNOWBALL, Elodie CHABROL