Patents by Inventor Dimitri MONOS

Dimitri MONOS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FUNCTIONAL TARGETS OF MIR-6891-5P & APPLICATIONS THEREOF
    Publication number: 20210095342
    Abstract: The present disclosure relates to the involvement of HSA-miR-6891-5p in immune and/or inflammatory disorders, as well as the use of agonists/antagonists thereof to treat the same.
    Type: Application
    Filed: May 9, 2017
    Publication date: April 1, 2021
    Applicants: THE CHILDREN'S HOSPITAL OF PHILADELPHIA, THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Dimitri MONOS, Peter CLARK, Nilesh CHITNIS, Brad JOHNSON, Malek KAMOUN
  • METHODS OF IDENTIFYING MIRNAS AND APPLICATIONS THEREOF
    Publication number: 20200165609
    Abstract: Accurate mapping of RNA-Seq reads to the reference genome is critical for accurate identification and quantification of miRNA transcripts. The miRNA transcriptome of two homozygous lymphoblastoic cell lines with completely characterized MHC haplotypes (PGF and COX) was analyzed and revealed 89 novel mature miRNA transcripts originating from within the MHC, including three mature miRNA that are haplotype specific, one of which originates from within intron 5 of HLA-DRB5. This is a novel way to identify miRNA transcripts originating from the MHC in a variety of tissue types and disease states, and can be utilized to prepare personal genome assemblies.
    Type: Application
    Filed: May 10, 2018
    Publication date: May 28, 2020
    Applicant: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
    Inventors: Dimitri MONOS, Peter CLARK