Abstract: The present invention relates to an antibody, or an antigen-binding fragment thereof, specifically binding to APRIL for use in the prevention and/or treatment of hypertriglyceridemia, metabolic syndrome, non-alcoholic steatohepatitis, diabetes mellitus type 2, abdominal aortic aneurysm, atherogenic dyslipidemia, cardiovascular events (e.g., myocardial infarction and stroke) and/or atherosclerosis. The invention further relates to a polynucleotide that encodes and/or a pharmaceutical composition that comprises the antibody or an antigen-binding fragment of the invention. The invention also relates to a kit and/or method for quantifying the concentration of nc-APRIL, canonical APRIL or total APRIL in a sample. Further, the invention relates to a nephelometric assay for quantifying nc-APRIL.

Abstract: Technologies and techniques for operating a flying object, such as a battery-operated flying object that includes at least one battery system and at least one electric drive unit. During an emergency, a first power limit of the battery system can be increased to a second power limit of the battery system such that a safe emergency landing of the flying object is possible.

Abstract: A method and a device for adjusting the temperature of steel blanks, such that a plurality of temperature-adjusting stations are used in order to heat the steel blanks in stages with low temperature gradients.

Abstract: A device and method for tempering sections of hot-formed and/or press-hardened metal components is disclosed having a support structure and a work head, the work head having at least one contact element consisting of an electrically-conductive material, for heating sections of a metal component using a flow of heat. Electrodes for resistively heating the contact element are connected thereto, and to a current source. A hot-formed and/or press-hardened metal component is first provided, and at least one contact element mounted on a work head is heated to a temperature greater than a target temperature to which a section of the metal component is to be heated. A contact surface of said contact element then comes into full-surface contact with the metal component section to be heated, with a predetermined pressing force, such that the metal component is heated to a target temperature in at least some sections by a flow of heat. The contact element is thus heated using resistive heating.

Abstract: A device and method for tempering sections of hot-formed and/or press-hardened metal components is disclosed having a support structure and a work head, the work head having at least one contact element consisting of an electrically-conductive material, for heating sections of a metal component using a flow of heat. Electrodes for resistively heating the contact element are connected thereto, and to a current source. A hot-formed and/or press-hardened metal component is first provided, and at least one contact element mounted on a work head is heated to a temperature greater than a target temperature to which a section of the metal component is to be heated. A contact surface of said contact element then comes into full-surface contact with the metal component section to be heated, with a predetermined pressing force, such that the metal component is heated to a target temperature in at least some sections by a flow of heat. The contact element is thus heated using resistive heating.