Patents by Inventor Dimitris Kalaitzakis

Dimitris Kalaitzakis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOCONJUGATION REAGENT AND METHODS
    Publication number: 20220169604
    Abstract: The present invention in general relates to the field of bioconjugation. More in particular, the invention relates to novel bioconjugation reactants based on an ?,? unsaturated ?-hydroxylactam structure, amongst others allowing a higher degree of functionalization compared to classical bioconjugation reactants such as maleimide. The present invention also provides methods of preparing the novel bioconjugation reactants, as well as uses thereof in human and/or veterinary medicine; and conjugation processes.
    Type: Application
    Filed: February 28, 2020
    Publication date: June 2, 2022
    Applicant: Universiteit Gent
    Inventors: Annemieke Madder, Ewout De Geyter, Eirini Antonatou, Sabina Smolen, Dimitris Kalaitzakis, Georgios Vassilikogiannakis
  • Method of Making (+)- Sitophilure
    Publication number: 20090298147
    Abstract: (+)-Sitophilure, the aggregation pheromone of the pests rice weevil and maize weevil, is synthesized in high yield and diastereomeric excess by contacting 4-methyl-3,5heptadione with a reduced nicotinamide cofactor and a ketoreductase enzyme capable of catalyzing the reduction of 4-methyl-3,5-heptadione to produce (4R,5S)-5-hydroxy-4-methyl-3-heptanone to the substantial exclusion of other diastereomers.
    Type: Application
    Filed: December 22, 2006
    Publication date: December 3, 2009
    Inventors: Dimitris Kalaitzakis, J. David Rozzeli, Spiros Kambourakis, Ioulia Smonou