Patents by Inventor Dimitrois Sarantakis

Dimitrois Sarantakis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Analgesic polypeptide
    Patent number: 4148786
    Abstract: The polypeptides of the formula: ##STR1## in which R.sup.1 is hydrogen, lower alkyl, allyl, 2-isopentenyl, 3-isopentenyl, cyclopropylmethyl, cyclobutylmethyl, phenethyl or arginyl;R.sup.2 is hydrogen or lower alkyl;R.sup.3 is hydrogen or lower alkyl;R.sup.4 is hydrogen, hydroxymethyl, carbo(lower)alkoxy, carbamyl or carboxy; andX is hydrogen, chloro, fluoro, bromo or iodo, the linear precursors thereof or a pharmaceutically acceptable salt thereof,Exert an analgesic effect in warm-blooded animals when peripherally administered.
    Type: Grant
    Filed: June 26, 1978
    Date of Patent: April 10, 1979
    Assignee: American Home Products Corporation
    Inventor: Dimitrois Sarantakis
  • Hexapeptides having analgesic activities
    Patent number: 4143032
    Abstract: Hexapeptides of the formula:H-Arg-Tyr-X-Gly-Phe-Y-Zwherein X is D-Ala, D-Met, D-Leu, D-Pro, D-His, D-Trp or D-Phe; Y is D-Leu, D-Met, D-Pro or D-Lys; and Z is --OH, --NH.sub.2, or --NHC.sub.2 H.sub.2n+1 where n is 1, 2, 3, or 4 or a pharmaceutically acceptable salt thereof, exert an analgesic effect in warm-blooded animals upon intravenous administration.
    Type: Grant
    Filed: June 20, 1977
    Date of Patent: March 6, 1979
    Assignee: American Home Products Corporation
    Inventor: Dimitrois Sarantakis
  • Arg .sup.4 -somatostatin and analogues thereof
    Patent number: 4061608
    Abstract: Polypeptides of the formula: ##STR1## THE LINEAR PRECURSORS, INTERMEDIATES AND NON-TOXIC ACID ADDITION SALTS THEREOF, WHEREINR is hydrogen or Ala-GlyAndX.sub.8 is L-Trp or D-TrpAre described. These polypeptides inhibit the secretion of growth hormone and, at low doses, excel in their higher glucagon to insulin lowering ratio.
    Type: Grant
    Filed: July 13, 1976
    Date of Patent: December 6, 1977
    Assignee: American Home Products Corporation
    Inventor: Dimitrois Sarantakis